Results 211 to 220 of about 91,544 (273)

Mechanisms of action and clinical development of elotuzumab [PDF]

, 2017
Colonna, Marco, Ritchie, David
core   +2 more sources

Evolution of hematopoietic stem cell potential from preterm to term neonates

HemaSphere, Volume 10, Issue 2, February 2026.
Pamela Quaranta, Luca Basso‐Ricci, Luca Seffin, Guido Pacini, Andrea Ronchi, Riccardo Crimi, Monica Fumagalli, Carlo Pietrasanta, Serena Scala   +8 more
wiley   +1 more source

Tumor Microenvironments in Malignant Ovarian Germ Cell Tumors: MHC Class I Loss and T‐Cell Exhaustion in Dysgerminoma

Cancer Science, Volume 117, Issue 2, Page 566-575, February 2026.
Malignant ovarian germ cell tumor subtypes exhibit distinct tumor microenvironments. Dysgerminomas harbor abundant nonexhausted T cells, with progenitor exhausted T cells present in 60% of PD‐1–positive cases. However, MHC class I expression is lost across all analyzed subtypes, suggesting that restoring class I expression in dysgerminomas may enhance ...
Miya Nakashima, Takeshi Iwasaki, Yoshihiro Katayama, Masatoshi Shimo, Ken Takigawa, Naomi Shimada, Michiko Matsushita, Satoshi Kuwamoto, Shinya Sato, Masato Toya, Kohta Miyawaki, Koichi Akashi, Kiyoko Kato, Yoshinao Oda   +13 more
wiley   +1 more source

Combined Anti-CD20/Anti-CD38 Therapy in Posttransplant Focal Segmental Glomerulosclerosis Recurrence: A Retrospective, International, Multicenter Study. [PDF]

Transplant Direct
Cravedi P, Maggiore U, Mortari G, Alberici F, La Manna G, Goes N, Bouvier N, Comai G, Mehr AP, Gentile M, Palmisano A, Gessaroli E, Barbuto S, Caridi G, Bigatti C, Magnasco A, Bossini N, Kajana X, Spennacchio A, Gallon L, Ghiggeri GM, Vincenti F, Hullekes FE, Mehta RV, Riella LV, Verrina EE, Angeletti A.   +26 more
europepmc   +1 more source

Liquid–Liquid Phase Separation in Major Hallmarks of Cancer

Cell Proliferation, Volume 59, Issue 2, February 2026.
Aberrant condensates formed through phase separation are involved in the dysregulation of various critical cellular processes, including genome stability, transcriptional regulation and signal transduction, thereby promoting malignant transformation and the acquisition of multiple cancer hallmarks.
Chen‐chen Xie, Ting Wang, Xin‐ran Liu, Yan Wang, Qin Dang, Tian Ding, Jia‐qi Xu, Xian‐jun Yu, Hai Lin, Xiao‐wu Xu, Yi Qin   +10 more
wiley   +1 more source

Unveiling the mediating role of immune cells in the link between pathogen infections and Hashimoto's thyroiditis. [PDF]

J Int Med Res
Zhou J, Xu Y, Wang H, Chen C, Wang K.
europepmc   +1 more source

Humoral epitope dominance and immune imprinting by SARS‐CoV‐1 and SARS‐CoV‐2 vaccines

Immunology &Cell Biology, Volume 104, Issue 2, Page 150-167, February 2026.
We investigated Modified Vaccinia Ankara (MVA) vaccine candidates expressing the SARS‐CoV‐1 or SARS‐CoV‐2 Spike, as a primary or booster immunization, for their ability to induce antibodies targeting different epitopes on the SARS‐CoV‐2 RBD and broad cross‐reactive or cross‐neutralizing responses in C57BL/6 and antibody humanized (Ig‐humanized) mice ...
Deborah L Burnett, Ania Moxon, Anupriya Aggarwal, Katherine JL Jackson, Catherine Cotter, Anouschka Akerman, Amanda Russell, Rachel Kalman, David Langley, Jake Y Henry, Daniel Christ, Rowena A Bull, Robert Brink, Anthony D Kelleher, Hans‐Martin Jäck, Stuart Turville, Bernard Moss, Christopher C Goodnow   +17 more
wiley   +1 more source

Dysregulation of Niacin-Derived NAD⁺ Salvage Pathway Markers (CD38, NAMPT, SIRT1) Across Albuminuria Stages in Type 2 Diabetes. [PDF]

Medicina (Kaunas)
Huwaimel B, Alqarni S, Abouzied AS, Alghubayshi A, Alotaibi T, Elshafei A, Yassien M, Nasr M, Khidr EG.   +8 more
europepmc   +1 more source

T Cell Exhaustion in Hepatocellular Carcinoma: A Substantial Barrier in Immunotherapy

Journal of Cellular and Molecular Medicine, Volume 30, Issue 3, February 2026.
ABSTRACT Hepatocellular carcinoma (HCC), accounting for over 90% of primary liver cancers, remains a major global challenge for healthcare professionals. While immunotherapy has transformed the landscape of cancer treatment, its success is often limited by immune resistance, particularly through T cell exhaustion which remains a major barrier to ...
Kosar Nouri, Negar Asadollahei, Yasamin Haghir‐Sharif‐Zamini, Homeyra Seydi, Mahsa Salehi, Mehrnaz Mesdaghi, Mustapha Najimi, Massoud Vosough   +7 more
wiley   +1 more source

Long-term high-protein diet intake accelerates adipocyte senescence through macrophage CD38-mediated NAD⁺ depletion. [PDF]

Mol Metab
Yang X, Hua L, Gao D, Wu Y, Yang Y, Jin X, Jiang X, Jin C, Feng B, Che L, Xu S, Lin Y, Jin L, Zhuo Y, Li M, Wu.   +15 more
europepmc   +1 more source