Results 231 to 240 of about 67,119 (304)

Efficacy and safety of elranatamab in patients with relapsed or refractory multiple myeloma: A US subgroup analysis from MagnetisMM‐3

Cancer, Volume 132, Issue 11, 1 June 2026.
Abstract Introduction Elranatamab, approved for relapsed or refractory multiple myeloma, demonstrated deep, durable responses and manageable safety in patients without prior B‐cell maturation antigen (BCMA)‐directed therapy (BCMA‐naive) in MagnetisMM‐3 (NCT04649359). This post hoc analysis evaluated efficacy and safety in the US subgroup.
Ajay K. Nooka, Christopher Strouse, Sarah M. Larson, Alexander Lesokhin, Asya Varshavsky‐Yanovsky, David H. Vesole, Guenther Koehne, Elpitha Soussou, Sharon T. Sullivan, Jay Cheng, Noopur Raje   +10 more
wiley   +1 more source

Characteristics, treatment regimens, and outcomes of patients with true extramedullary multiple myeloma: a real-world monocentric analysis. [PDF]

Ann Hematol
Harzer M, Gross-Fengels N, Melzer F, Molwitz I, Kosch R, Al-Bazaz M, Artzenroth J, Cords L, Bartke L, Kamili A, Alsdorf W, Bokemeyer C, Weisel K, Leypoldt LB, Schaefers C.   +14 more
europepmc   +1 more source

Resolving the renal microenvironment: a 5-plex immunofluorescence workflow to quantify B-lineage cells in FFPE lupus nephritis biopsies. [PDF]

Front Immunol
Chan C, Chang PS, Chalasani S, Tao J, Raghu H, Austin CD.   +5 more
europepmc   +1 more source

Enzymatic Synthesis of NAD+

Current Protocols, Volume 6, Issue 6, June 2026.
Abstract Nicotinamide adenine dinucleotide (NAD+) is an essential metabolite involved in numerous biological processes, functioning both as a redox cofactor in cellular energy metabolism and as a co‐substrate for NAD+‐utilizing enzymes, including sirtuins and poly(ADP‐ribose) polymerases.
Emily Boyle, Olivia Zhang, Yana Cen
wiley   +1 more source

Emerging therapeutic advances for immune thrombocytopenia: highlights from selected early‑phase and pivotal trials at the 2025 ASH annual meeting. [PDF]

Exp Hematol Oncol
Cao L, Wang Z, Xiang Q.
europepmc   +1 more source

Single‐cell and repertoire profiling reveals immune remodelling in paediatric upper airway: insights from adenoid hypertrophy

Clinical &Translational Immunology, Volume 15, Issue 6, 2026.
Single‐cell and paired V(D)J profiling show that paediatric adenoid hypertrophy features expanded proliferative germinal‐centre B cells with impaired maturation. Abstract Objectives To characterise the immune cellular landscape and paired B‐cell and T‐cell receptor repertoires of hypertrophic adenoids in children with obstructive sleep apnoea.
Chao Wang, Yufei Pan, Xiao Han, Kai Sun, Jing Li, Yuanyuan Lu, Zhenkun Yu   +6 more
wiley   +1 more source

Role of hypertrophic adipocytes, collagen VI, and CD38 in adipose tissue fibrosis in obesity. [PDF]

Sci Rep
Di Vincenzo A, Luca T, Perugini J, Lezoche G, Barresi V, De Geronimo V, Donati A, Casarotta E, Tomasello M, Pezzino S, Scuderi C, Di Cristoforo A, Pieroni A, Petrelli M, Napoli MV, Figueiredo N, Corgosinho FC, Sbarbati A, Merlini L, Sabatelli P, Graciotti L, Spadoni T, Dani C, Mattioli-Belmonte M, Condorelli DF, Gabrielli A, Malavasi F, Giordano A, Castorina S, Cinti S.   +29 more
europepmc   +1 more source

Effect of CXCR5, PD‐1 and ICOS on B‐cell responses and relevance to myasthenia gravis

Clinical &Translational Immunology, Volume 15, Issue 6, 2026.
This study compared the efficacy of PD‐1 and ICOS molecules in antibody production within CXCR5+ and CXCR5− CD4+ T cells; it demonstrates that PD‐1+ T cells provide the most effective B cell support, a finding also validated in autoantibody production in myasthenia gravis.
Merve Çebi, Arman Çakar, Hacer Durmuş, Yeşim Parman, Güher Saruhan‐Direskeneli   +4 more
wiley   +1 more source

Association between CD56, CD38 and chronic endometritis and analysis of pregnancy prognosis: a single-center retrospective cohort study. [PDF]

Front Med (Lausanne)
Kong Y, Zhou S, Zhou Q.
europepmc   +1 more source

Characterization of Harderian Gland‐Derived Plasma Cells in Chicken

European Journal of Immunology, Volume 56, Issue 6, June 2026.
An isolation protocol for plasma cells (PC) from the chicken Harderian gland (HG) was established, and analyses of PCs revealed a FSChigh/CD45med/sIgpos/CD57pos/CXCR4high/TACIlow phenotype. Presence of CXCL12 and BAFF around HG PCs suggests a contribution of CXCL12–CXCR4 and BAFF–TACI to PC localization and survival.
D. von La Roche, I. Naumann, E. Szőcs, V. Halasy, M. Kohn, B. Kaspers, N. Nagy, S. Härtle   +7 more
wiley   +1 more source