Results 201 to 210 of about 92,020 (286)

A Decline in Follicle Cell Function Is a Major Driver of Drosophila Ovarian Aging

Aging Cell, Volume 25, Issue 5, May 2026.
Aging drives a progressive accumulation of defects in somatic follicle cells of the Drosophila ovary. These defects are accompanied by reduced tissue and genome integrity, altered transcriptional profiles, and disrupted germ‐soma coordination. Targeted overexpression of Atg8a in a subset of follicle cells mitigates these defects and preserves ...
Emily A. Wolfgram, Todd G. Nystul
wiley   +1 more source

On-Resin DIAMSAR-Conjugated CD38-Targeted Peptides and Their Inverso and Dimeric-Inverso Analogs for PET Imaging of Multiple Myeloma. [PDF]

Bioconjug Chem
Sharma AK, Tang R, Zheleznyak A, Manion B, Teubner E, Prior JL, Bauer T, Dyer MR, Lees S, Kelly K, Shokeen M.   +10 more
europepmc   +1 more source

Elranatamab: Mechanism of Action, Clinical, and Translational Science

Clinical and Translational Science, Volume 19, Issue 5, May 2026.
ABSTRACT Elranatamab (ELREXFIO) is a humanized bispecific antibody approved for patients with relapsed/refractory multiple myeloma (RRMM). Elranatamab engages CD3 on T cells and B‐cell maturation antigen (BCMA) on myeloma cells to induce T cell–mediated myeloma cell cytolysis.
Mohamed Elmeliegy, Andrea Viqueira, Erik Vandendries, Pooneh Soltantabar, Hoi‐Kei Lon, Kamrine Poels, Blerta Shtylla, Donald Irby, Kristin Bompiani‐Myers, Thomas O'Brien, Jennifer Hibma   +10 more
wiley   +1 more source

Characterization of the activation status of T lymphocyte subpopulations in peripheral blood from localized and diffused cutaneous leishmaniasis patients at the University of Gondar Hospital, Ethiopia. [PDF]

BMC Infect Dis
Dubie T, Chanyalew M, Deressa T, Atnafu A, Debebe DG, Melese TW, Adem M, Tsehay D, Woldemariam M, Zewdie M, Gadisa E, Howe R.   +11 more
europepmc   +1 more source

Predicting Positive Affect in Infancy

Developmental Science, Volume 29, Issue 3, May 2026.
ABSTRACT Positive affect (PA) is integral to health and development, yet its early origins remain largely unexplored. In this pre‐registered study (N = 78), we investigated whether infant‐specific biological and social‐behavioral factors predict PA in early development.
Tobias Grossmann, Halle Miller, Olivia Allison   +2 more
wiley   +1 more source

High PD-1 expression in pre-treatment peripheral lymphocytes associated with poor immune checkpoint inhibitor response in patients with recurrent or metastatic head and neck squamous cell carcinoma. [PDF]

Cancer Immunol Immunother
Li SH, Huang WT.
europepmc   +1 more source

Survival and Renal Recovery in Newly Diagnosed Multiple Myeloma Patients Presenting With Dialysis‐Requiring Severe Renal Impairment

European Journal of Haematology, Volume 116, Issue 5, Page 577-584, May 2026.
ABSTRACT Background Severe renal insufficiency requiring dialysis in newly diagnosed multiple myeloma (NDMM) patients has been independently associated with poor survival outcomes. However, there is a paucity of data on factors predicting renal recovery and survival outcomes of these patients.
Rintu Sharma, Eshetu G. Atenafu, Esther Masih‐Khan, Harjot Vohra, Sita Bhella, Christine Chen, Vishal Kukreti, Guido Lancman, Anca Prica, A. Keith Stewart, Rodger Tiedemann, Suzanne Trudel, Chloe Yang, Donna Reece   +13 more
wiley   +1 more source

Atypical chronic lymphocytic leukemia with biallelic 13Q deletion. [PDF]

Hematol Transfus Cell Ther
Roldán Galiacho V, Altuna Tellechea L, Alonso Varela M, Diez de Lezcano Manrique deLara I.   +3 more
europepmc   +1 more source

CD38 Expressing Cell Count [PDF]

, 2020
openaire   +1 more source

Oxytocin Neuron‐Specific CAPS2 Deficiency in Mice Impairs Hippocampal Plasticity and Long‐Term Memory Through Reduced ERK Phosphorylation in the Ventral hippocampus

European Journal of Neuroscience, Volume 63, Issue 9, May 2026.
The CAPS2 cKO mouse, characterized by reduced oxytocin release, exhibits impaired cognitive function and disrupted hippocampal long‐term potentiation. ABSTRACT Oxytocin (OXT), a neuropeptide produced in the paraventricular nucleus (PVN) of the hypothalamus, regulates social behaviour, stress responses, and memory. Our previous studies demonstrated that
Wakana Nagano, Junpei Takahashi, Tsugumi Yamauchi, Daisuke Yamada, Yoshitake Sano, Teiichi Furuichi, Akiyoshi Saitoh   +6 more
wiley   +1 more source