Results 41 to 50 of about 780,218 (307)

Tapak liman (Elephantopus scaber L) Extract Induced CD4+ and CD8+ Differentiation from Hematopoietic Stem Cell/Progenitor Cell Proliferation of Mice (Mus musculus)

Journal of Experimental Life Science, 2015
Tapak liman (Elephantopus scaber L) is one of the traditional medicinal plants, which are containing several active compounds that potentially affecting hematopoietic.
M. Sasmito Djati, Hindun Habibu, Nabilah A Jatiatmaja, Muhaimin Rifa'i   +3 more
doaj   +1 more source

Pan-cancer landscape of aberrant DNA Methylation across childhood Cancers: Molecular Characteristics and Clinical relevance

Experimental Hematology & Oncology, 2022
Aberrant DNA methylation (DNAm) is an important epigenetic regulator in various cancers. Pan-cancer DNAm analyses have investigated the potential common mechanisms of DNAm in tumorigenesis.
Zheng Dong, Hongyu Zhou
doaj   +1 more source

Modulation of CD4 by suramin [PDF]

Clinical and Experimental Immunology, 1993
SUMMARYSuramin is a polysulphonated compound which can selectively bind to, and inhibit the activity of, a wide range of growth factors. There has been renewed interest recently in suramin as an anti-cancer agent and therefore we have studied its effects on lymphocyte subset populations and recombinant human IL-2 (rhIL-2) activation on lymphocytes in ...
P D, Allen, D H, Johnston, M G, Macey, N S, Williams, A C, Newland   +4 more
openaire   +2 more sources

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

FEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante, Robert Sharp, Pradip K. Saha, Elizabeth S. Anaya, Elizabeth L. Lieu, Evelyn L. de Groot, Pooja Patel, Mi Jeong Heo, Aaron R. Cox, Kang Ho Kim, Sean M. Hartig   +10 more
wiley   +1 more source

Imbalanced T-Cell Subsets May Facilitate the Occurrence of Osteonecrosis of the Femoral Head

Journal of Inflammation Research, 2022
Changjun Chen,1 Xin Zhao,1,2 Yue Luo,1 Bohua Li,1 Qianhao Li,1 Chengcheng Zhao,1 Yan Huang,3 Pengde Kang1 1Department of Orthopedics, West China Hospital, Sichuan University, Chengdu, People’s Republic of China; 2Department of Orthopedics, Shandong ...
Chen C, Zhao X, Luo Y, Li B, Li Q, Zhao C, Huang Y, Kang P   +7 more
doaj  

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

Molecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura, Tadahiro Kuribayashi, Johannes Brägelmann, Sachi Okawa, Masataka Taoka, Shunta Mori, Tomoka Nishimura, Takaaki Tanaka, Go Makimoto, Kiichiro Ninomiya, Kammei Rai, Eiki Ichihara, Ryohei Katayama, Katsuyuki Hotta, Masahiro Tabata, Yosuke Togashi, Yoshinobu Maeda, Martin L. Sos, Katsuyuki Kiura, Kadoaki Ohashi   +19 more
wiley   +1 more source

Role of CD4 epitopes outside the gp120-binding site during entry of human immunodeficiency virus type 1 [PDF]

, 1997
CD4 is the primary receptor for human immunodeficiency virus (HIV). The binding site for the surface glycoprotein of HIV type 1 (HIV-1), gp120, has been mapped to the C'-C" region of domain 1 of CD4. Previously, we have shown that a mutant of rat CD4, in
Puklavec, M., Stumbles, P.A., James, W, Barclay, AN, James, W., Sattentau, QJ, Stumbles, P, Somoza, C, Somoza, C., Signoret, N., Simon, J.H.M, Simon, JH, Puklavec, M, Sattentau, Q.J., Sattentau, Quentin, Barclay, A.N., Signoret, N, James, William   +17 more
core  

The function and origin of the CD4+ T cell in the classical Hodgkin lymphoma microenvironment [PDF]

, 2012
PhDClassical Hodgkin lymphoma (CHL) is a germinal centre B cell malignancy where the bulk of the tumour comprises a non-clonal immune infiltrate enriched for CD4+ T cells.
Greaves, Paul
core   +4 more sources

Effects of Crescentia cujete (L.) fruit extract on the profile of hematology of ranchu goldfish (Carassius auratus)

Open Veterinary Journal
Background: Disease prevention in cultivating ranchu goldfish (Carassius auratus) can be prevented by giving immunostimulants in the food. One immunostimulant can come from herbs such as calabash fruit (Crescentia cujete L.). Aim: This study aims to
Felician Lestari Wongkar, Yos Adi Prakoso, Agustina Dwi Wijayanti   +2 more
doaj   +1 more source

The treatment dynamics assessment among patients with chronic viral hepatitis B, infected with human immunodeficiency virus

Journal of Education, Health and Sport, 2020
Introduction: the article represents prospective study results of the treatment dynamics among patients with chronic viral hepatitis B, infected with human immunodeficiency virus.
L. V. Moroz, T. O. Melnyk
doaj   +1 more source