Results 51 to 60 of about 782,392 (306)

Metastatic niche shaped by host factors influences disseminated cancer cell fate

FEBS Letters, EarlyView.
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward, Álvaro Ruiz‐Tabas, Patricia Altea‐Manzano   +2 more
wiley   +1 more source

The rate of CD4 decline as a determinant of progression to AIDS independent of the most recent CD4 count [PDF]

, 1998
The data of two cohort studies of HIV-infected individuals were used to examine whether the rate of CD4 decline is a determinant of HIV progression, independent of the most recent CD4 count.
Lepri, AC, Phillips, AN, Lee, CA, Pezzotti, P, Rezza, G, Sabin, CA   +5 more
core  

Atypical CD3+ CD4(low) cell population in a boy with fatal EBV-infection [PDF]

, 1999
A previously healthy 10-year-old Greek boy born to nonconsanguineous healthy parents developed progressive liver disease after acute infectious mononucleosis.
Krauss-Etschmann, Susanne, Belohradsky, Bernd H., Gruber, Rudolf, Jäger, Gundula, Koletzko, Sibylle   +4 more
core   +1 more source

Estrogen and progesterone attenuate CD4-positive immune cell traffic to the penumbra region of rat’s ischemic stroke brain [PDF]

Iranian Journal of Basic Medical Sciences
Objective(s): Stroke is an acute cerebrovascular disease with a high incidence, high disability rate, and high mortality. Stroke damages the integrity of the blood-brain barrier.
Aboutaleb Tamtaji, Sayyed Alireza Talaei, Homayoun Naderian, Mohammad Ali Atlasi, Nasim Alipour, Abolfazl Azami-Tameh   +5 more
doaj   +1 more source

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

Molecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura, Tadahiro Kuribayashi, Johannes Brägelmann, Sachi Okawa, Masataka Taoka, Shunta Mori, Tomoka Nishimura, Takaaki Tanaka, Go Makimoto, Kiichiro Ninomiya, Kammei Rai, Eiki Ichihara, Ryohei Katayama, Katsuyuki Hotta, Masahiro Tabata, Yosuke Togashi, Yoshinobu Maeda, Martin L. Sos, Katsuyuki Kiura, Kadoaki Ohashi   +19 more
wiley   +1 more source

Viewpoint: Why do we need a point-of-care CD4 test for low-income countries? [PDF]

, 2010
In this paper, we discuss the reasons why we urgently need a point-of-care (POC) CD4 test, elaborate the problems we have experienced with the current technology which hampers CD4-count coverage and highlight the ideal characteristics of a universal CD4 ...
Harries, AD, Reid, S D, Harries, A D, A. D. Harries, Chaillet, P, Reid, SD, S. D. Reid, Zachariah, R, P. Chaillet, R. Zachariah, Massaquoi, M, Schouten, EJ, E. J. Schouten, M. Massaquoi, Schouten, E J   +14 more
core   +1 more source

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

Molecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola, Yasmine Illi, Anna Bircher, Marijn Wilmink, Rachele F. Malagutti, Solenn Ottié, Cordelia Schuler, Pedro A. Ruiz, Cheryl de Vallière, Klaus Seuwen, Gerhard Rogler, Martin Hausmann   +11 more
wiley   +1 more source

Understanding the slow depletion of memory CD4(+) T cells in HIV infection [PDF]

, 2007
Background The asymptomatic phase of HIV infection is characterised by a slow decline of peripheral blood CD4(+) T cells. Why this decline is slow is not understood.
Nigel Klein, Klein Nigel, Antia, Rustom, Yates, Andrew, Callard, Robin, Antia Rustom, Yates, A, Callard, R, Klein, Nigel, Jaroslav Stark, Stark, J, Andrew Yates, Stark Jaroslav, Rustom Antia, Callard Robin, Stark, Jaroslav, Yates Andrew, Robin Callard, Klein, N, Antia, R   +19 more
core   +2 more sources

Clinico-demographic profile of patients with HIV/tuberculosis co-infection from western Gujarat, India: a retrospective study

HIV & AIDS Review. International Journal of HIV-Related Problems
Introduction Human immunodeficiency virus (HIV)/tuberculosis (TB) co-infection has become huge barrier to achieving TB control in the world. TB, despite being discovered in 1882, remains a major public health problem in many developing countries.
Parth U. Patel, Chandra S. Purohit, Kalpesh B. Patel   +2 more
doaj   +1 more source

Profil Angular Cheilitis pada penderita HIV/AIDS di UPIPI RSUD Dr. Soetomo Surabaya 2014

Majalah Kedokteran Gigi Indonesia, 2015
Profile of Angular Cheilitis in HIV/AIDS Patients at UPIPI RSUD Dr. Soetomo Surabaya 2014. For over twenty years, human immunodeficiency virus (HIV) infection and acquired immunodeficiency syndrome (AIDS) have become a significant public health concern ...
Alexander Patera Nugraha, Mintarsih Djamhari K, Adiastuti Endah P, Bagus Soebadi, Erwin Asta Triyono, Remita Adya Prasetyo, Sulistyowati Budi   +6 more
doaj   +1 more source