Results 171 to 180 of about 782,392 (306)

Elevated RIPK2 Expression in Atopic Dermatitis Skin Is Associated with Mixed Th1/Th2 Cytokine Responses in CD4⁺ T Cells. [PDF]

Int J Mol Sci
Mubariki R, Khamaysi Z, Kaabour E, Salih M, Belity T, Toubi E, Blacher E, Vadasz Z.   +7 more
europepmc   +1 more source

Engineering‐Modulated Molybdenum Enzymes Strategy for Tumor‐Specific Metabolic‐Immunotherapy

Advanced Science, EarlyView.
Biodegradable molybdenum sulfide nanoparticles were synthesized via a one‐pot strategy to increase molybdenum enzyme activity and thus effectively potentiate anti‐tumor immunity by integrating molybdenum‐based metalloimmunotherapy with hydrogen sulfide gas therapy.
Xiaoxiao Pan, Zifan Pei, Jie Wu, Nan Jiang, Qian Li, Yuqi Yang, Jie Cao, Yechen Huang, Shumin Sun, Qialu Du, Zhicheng Liu, Lin Zhang, Fei Gong, Jinhua Zhou, Liang Cheng   +14 more
wiley   +1 more source

Integrated Single‐Cell and TCR Profiling Reveals Protection‐Associated CD8+ T Cell Subsets Linked to Viral Control in PRRSV

Advanced Science, EarlyView.
PRRSV vaccine‐mediated protection is associated with clonally expanded cytotoxic CD8+ T cell subsets driven by viral structural proteins and supported by innate TLR4/TLR8 signaling and CD4+ T cell help, whereas non‐protective responses are characterized by dysfunctional exhausted‐like CD8+ T cells linked to poor viral control.
Can Kong, Siang Chen, Maolin Li, Meng Wang, Hailin Zhang, Bolun Zhou, Zhenhua Xie, Chen Wang, Peng Gao, Jianjun Luo, Hanchun Yang, Runsheng Chen, Dongdong Zhang, Jie Li, Jun Han   +14 more
wiley   +1 more source

Upadacitinib Restrains the Pathogenic Fitness of CD4⁺ T Cells and Aberrant B Cell Programming in Optic Neuritis. [PDF]

Adv Sci (Weinh)
Jiang G, Jiang Q, Han L, Peng Y, Liu X, Yang T, Huang H, Liu J, Gao Y, Yang H, Zou W, Li Z, Su W.   +12 more
europepmc   +1 more source

Deep Learning Prediction of O‐Glycopeptide Tandem Mass Spectra Enhances O‐Glycoproteomics

Advanced Science, EarlyView.
DeepGPO integrates Transformer and graph neural networks with tailored training strategies, including data augmentation, loss re‐weighting, and pre‐training, to achieve high‐quality O‐glycopeptide MS/MS spectra prediction. The predicted MS/MS spectra are used to localize O‐glycosylation sites from HCD MS/MS data, enhancing O‐glycoproteomics analysis ...
Yu Zong, Yuxin Wang, Liang Qiao
wiley   +1 more source

Factors Affecting Changes in CD4+ T-cell Count Among People Living with HIV (PLWH): A Retrospective Cohort Study in Kermanshah, Iran. [PDF]

HIV AIDS (Auckl)
Mohammadnezamian A, Ghadiri K, Rostamian M, Solouki L, Azadian M, Andayeshgar B, Shahbazi S, Chegene Lorestani R, Javadirad E.   +8 more
europepmc   +1 more source

CD4 [PDF]

Science-Business eXchange, 2013
openaire   +1 more source

Engineering a 660 nm‐Responsive Optogenetic Inducer of Pyroptosis for Precision Cancer Therapy

Advanced Science, EarlyView.
This study reports a bioorthogonal pyroptosis inducer, PyroRACS. By using a red‐light‐responsive Cre‐On genetic switch to control the expression of highly cytotoxic GSDMDNT, PyroRACS enables the artificial induction of pyroptosis with precise spatiotemporal control.
Mengkai Zhang, Zhichao Li, Yonghao Ma, Yangyang Sun, Wei Chen, Weiren Huang   +5 more
wiley   +1 more source

CD4 cell-monitored treatment interruption in patients with a CD4 cell count > 500 x 106 cells/l

, 2005
BACKGROUND: Little is known about CD4 cell count changes in patients with high CD4 cell counts who interrupt antiretroviral therapy, especially in those with a nadir of 250-350 x 10 cells/l.
A. d'Arminio Monforte, L. Sighinolfi, V. Borghi, International Study Group on CD4 monitored Treatment Interruptions, P. Ortolani, A. De Luca, A. Bedini, R. Enilia, A. Cozzi Lepri, R. Esposito, E. Barchi, A. Cossarizza, A. Antinori, S. Di Giambenedetto, A. N. Philips, C. Mussini, G. Guaraldi, G. Bratt, L. E. Eriksson   +18 more
core  

HIV-1 Vpr Drives a B Cell-Like Phenotype in Primary CD4⁺ T Cells. [PDF]

MedComm (2020)
Wang P, Li J, Wang W, Meng Z, Wu H, Du S, Deng K, Cai J.   +7 more
europepmc   +1 more source