Results 11 to 20 of about 780,218 (307)

Insights into the interaction of CD4 with anti-CD4 antibodies

Immunobiology, 2017
Knowledge about the mechanism by which some antibodies can block HIV-1 entry is critical to our understanding of their function and may offer new avenues for controlling the adhesion of HIV-1 to the host cells. While much progress has been made, this mechanism remains unclear.
Van-Chien, Bui, Thi-Huong, Nguyen
openaire   +2 more sources

Epidemiology and results of the first line therapy for HIV-related Hodgkin lymphoma

Учёные записки Санкт-Петербургского государственного медицинского университета им. Акад. И.П. Павлова, 2022
Introduction. The risk of developing Hodgkin lymphoma (HL) with HIV infection is higher than in the general population, and the course of the disease itself is more aggressive.
A. M. Chekalov, M. O. Popova, I. V. Tsygankov, Yu. A. Rogacheva, N. P. Volkov, K. V. Lepik, M. V. Demchenkova, T. V. Schneider, Yu. V. Kopeikina, N. V. Medvedeva, I. S. Zyuzgin, E. S. Pavlyuchenko, A. N. Levanov, A. A. Myasnikov, E. V. Kariagina, N. B. Mikhailova, V. V. Baykov, A. D. Kulagin   +17 more
doaj   +1 more source

CD4 cell count recovery among HIV-infected patients with very advanced immunodeficiency commencing antiretroviral treatment in sub-Saharan Africa. [PDF]

, 2006
BACKGROUND: Patients accessing antiretroviral treatment (ART) programmes in sub-Saharan Africa frequently have very advanced immunodeficiency. Previous data suggest that such patients may have diminished capacity for CD4 cell count recovery.
Myer, Landon, Landon Myer, Lawn Stephen D, Wood Robin, Lawn, Stephen, Linda-Gail Bekker, Lawn, Stephen D, Robin Wood, Bekker, Linda-Gail, Bekker Linda-Gail, Myer Landon, Stephen D Lawn, Wood, Robin   +12 more
core   +2 more sources

Laboratory biomarkers and immunological modulation of sintilimab in gastric cancer: A meta-analysis focused on tumor markers and T-cell subsets [PDF]

Journal of Medical Biochemistry
Background: Sintilimab, a PD-1 inhibitor, has emerged as a promising immunotherapeutic agent in gastric cancer. However, its impact on laboratory-based biochemical markers and immune indicators remains underexplored.
Zhang Xian, Zhao Qiang, Tang Huafei, Qin Rui, Tian Ting, Li Congying, Ma Rui   +6 more
doaj   +1 more source

Enumeration of CD4+ T-Cells Using a Portable Microchip Count Platform in Tanzanian HIV-Infected Patients [PDF]

, 2011
Background CD4+ T-lymphocyte count (CD4 count) is a standard method used to monitor HIV-infected patients during anti-retroviral therapy (ART). The World Health Organization (WHO) has pointed out or recommended that a handheld, point-of-care, reliable,
Gurkan, U.A, Fawzi, Wafaie W., Demirci, Utkan, Moon, S., Demirci Utkan, Mugusi Ferdinand, Fawzi, W.W, Jeffrey Blander, Gurkan, Umut Atakan, Umut Atakan Gurkan, Kuritzkes, D.R, Wafaie W Fawzi, Blander Jeffrey, Moon, SangJun, Daniel R. Kuritzkes, Mugusi, F., SangJun Moon, Fawzi Wafaie W., Demirci, U., Kuritzkes Daniel R., Said Aboud, Said Aboud, S., Aboud, Said, Kuritzkes, Daniel R., Ferdinand Mugusi, Mugusi, Ferdinand, Aboud Said, Blander, Jeffrey, Gurkan Umut Atakan, Blander, J., Fawzi, Wafaie W, Daniel R Kuritzkes, Wafaie W. Fawzi, Moon SangJun, Kuritzkes, Daniel R, Utkan Demirci   +35 more
core   +2 more sources

CD4+count-guided interruption of antiretroviral treatment [PDF]

, 2006
BACKGROUND:Despite declines in morbidity and mortality with the use of combination antiretroviral therapy, its effectiveness is limited by adverse events, problems with adherence, and resistance of the human immunodeficiency virus (HIV).METHODS:We ...
Babiker, A, Lundgren, JD, Faetkenheuer, G., Rappoport, C, Hoy, Jennifer, El-Sadr, Wafaa, Arduino, RC, Grund, B, Abrams, DJ, Clumeck, Nathan, Strategies for Management of Antiretroviral Therapy (SMART) Stud, Clumeck, N., Gazzard, B, Neuhaus, J, Neaton, J. D., Lundgren, J. D., Darbyshire, J, Grund, Birgit, Hoy, J., Phillips, A., Fätkenheuer, Gerd, Neaton, James, Lundgren, Jens D, Cohn, D., Cohen, C. J., Mejia, JMR, Strategies Management Antiretrovir, Darbyshire, J., Emery, S, Klingman, Karin, Darbyshire, Janet, Markowitz, Norman, Emery, Sean, Cohn, David V., Cooper, David, Gordin, Fred, Emery, S., Losso, M, Losso, Marcello, Klingman, K, Neaton, JD, Clumeck, N, Markowitz, N., Babiker, Abdel, Cooper, D., Losso, M., Mejia, J. M. Ramos, Arduino, R. C., Gordin, F, Fatkenheuer, G, Cohen, Calvin, Hoy, J, Neuhaus, J., El-Sadr, W. M., Grund, B., Klingman, K., El-Sadr, WM, Cohn, D, Gazzard, Brian, Burman, William, Burman, W., Abrams, D, Cohen, CJ, Gazzard, B., Arduino, Roberto, Markowitz, N, Gordin, F., Babiker, A., Burman, W, Cooper, D, Abrams, D., Phillips, Andrew N., Phillips, A, Rappoport, C.   +73 more
core   +1 more source

Antiretroviral treatment cohort analysis using time-updated CD4 counts: assessment of bias with different analytic methods. [PDF]

, 2011
BACKGROUND: Survival analysis using time-updated CD4+ counts during antiretroviral therapy is frequently employed to determine risk of clinical events.
Lewis, James J, Judith R. Glynn, Richard G White, James J Lewis, Middelkoop, Keren, Glynn, Judith R., Glynn, Judith R, Stephen D. Lawn, White, Richard G, Katharina Kranzer, Linda-Gail Bekker, James J. Lewis, White, Richard G., Lawn, Stephen D., Lawn, Stephen D, Judith R Glynn, Robin Wood, Lewis, James J., Bekker, Linda-Gail, Stephen D Lawn, Kranzer, Katharina, Richard G. White, Wood, Robin, Keren Middelkoop   +23 more
core   +1 more source

Modulation of the CD8+-T-cell response by CD4+ CD25+ regulatory T cells in patients with Hepatitis B virus infection [PDF]

, 2005
CD4+ CD25+ regulatory T cells have been shown to maintain peripheral tolerance against self and foreign antigens. In this study we analyzed the effect of circulating CD4+ CD25+ T cells on CD8+-T-cell responses of patients with chronic and resolved ...
Gotto, J, Ornella Franzese, Antonio Bertoletti, Maini, Mk, Franzese, O., Williams, R., Adam J. Gehring, Gehring, A.J., Roger Williams, Gehring, Aj, Gotto, J., Bertoletti, A., Kennedy, P.T.F., Williams, R, Maini, M.K., Patrick T. F. Kennedy, Kennedy, Ptf, Jim Gotto, Mala K. Maini, FRANZESE, ORNELLA   +19 more
core   +1 more source

CD4+CD25+ TR cells suppress innate immune pathology through cytokine-dependent mechanisms [PDF]

, 2003
Copyright @ 2003 The Rockefeller University PressCD4+CD25+ regulatory T (TR) cells can inhibit a variety of autoimmune and inflammatory diseases, but the precise mechanisms by which they suppress immune responses in vivo remain unresolved.
Maloy, Kevin, Fiona Powrie, Maloy, Kevin J., Gordon Dougan, Powrie, Fiona, Dougan, Gordon, Saunders, Nigel, Laurence Salaun, Cahill, R, Saunders, NJ, Saunders, Nigel J., Nigel J. Saunders, Salaun, L, Powrie, F, Rachel Cahill, Kevin J. Maloy, Salaun, Laurence, Maloy, KJ, Dougan, G, Cahill, Rachel   +19 more
core   +1 more source

IL-21: The Future of Medicine [PDF]

Journal of Clinical and Diagnostic Research, 2017
Interleukin-21 (IL-21), a T- cell-derived cytokine, is a signaling molecule secreted by a subpopulation of T cells called follicular T helper (Tfh) cells.
Syed Raza Shah, Muhammad Ahmed Jangda, Mohammad Danial Yaqub, Ayesha Altaf Jangda, Maham Khan, Brian Tomkins   +5 more
doaj   +1 more source