Results 21 to 30 of about 727,847 (314)

Study of CD4+, CD8+, and natural killer cells (CD16+, CD56+) in children with immune thrombocytopenic purpura

Hematology/Oncology and Stem Cell Therapy, 2017
Objective/background: To assess the percentage of CD4+, CD8+, and natural killer cells (CD16+, CD56+) in children with immune thrombocytopenic purpura (ITP) at presentation and study their impact on disease chronicity.
Farida Hussein El-Rashedi, Mahmoud Ahmed El-Hawy, Mohamed Ahmed Helwa, Sameh Said Abd-Allah   +3 more
doaj   +1 more source

Ocular manifestations in HIV patients attending a tertiary care hospital in Eastern India and correlation of posterior segment lesions with CD4+ counts

Indian Journal of Ophthalmology, 2023
Purpose: We aimed to study the ocular manifestations in human immunodeficiency virus (HIV)-infected patients and the correlation of posterior segment lesions with CD4+ counts.
Jyotirmayee Swain, Pramod Kumar Sharma, Loknath Mohanty, Pradeep Kumar Panigrahi   +3 more
doaj   +1 more source

Laboratory biomarkers and immunological modulation of sintilimab in gastric cancer: A meta-analysis focused on tumor markers and T-cell subsets [PDF]

Journal of Medical Biochemistry
Background: Sintilimab, a PD-1 inhibitor, has emerged as a promising immunotherapeutic agent in gastric cancer. However, its impact on laboratory-based biochemical markers and immune indicators remains underexplored.
Zhang Xian, Zhao Qiang, Tang Huafei, Qin Rui, Tian Ting, Li Congying, Ma Rui   +6 more
doaj   +1 more source

CD4 cell count and the risk of AIDS or death in HIV-Infected adults on combination antiretroviral therapy with a suppressed viral load: a longitudinal cohort study from COHERE. [PDF]

, 2012
BACKGROUND: Most adults infected with HIV achieve viral suppression within a year of starting combination antiretroviral therapy (cART). It is important to understand the risk of AIDS events or death for patients with a suppressed viral load.
S. Matheron, M. Sharland, Niels Obel (135891), R. Thiebaut, Jesper Grarup (453101), José M Miro, Reiss, Peter, Furrer, H, D. Haerry, A. Cozzi Lepri, Josefa Muñoz (11702276), Miró Meda, José M. (José María), 1956-, Hansjakob Furrer (93994), Ole Kirk (314889), Gazzard, B, G. Touloumi, Raffi, F, Josefa Muñoz, J. Reekie, A. Castagna, G. Fatkenheuer, R. Lodwick, Niels Obel, Sophie Grabar (697347), S. Grabar, T. Goetghebuer, J. Grarup, The Opportunistic Infections Project Team of the Collaboration o (16174457), D. Gibb, A. Antinori, Peter Reiss (4933), E. Girardi, José M Miro (16174463), Raffi, Francois, Antonella Castagna (255402), Grarup, Jesper, F. Engsig, Peter Reiss, Kirk, Ole, F. Gutierrez, Opportunistic Infections Project Team of the Collaboration of Ob,, H. Furrer, J. Casabona, M. Egger, O. Lambotte, Sylvie Ayayi (16174460), J. Ghosn, V. Bouteloup, Obel, N, Young, Jim, De Wit, Stéphane, Chêne, Geneviève, Heiner Bucher, M. Psichogiou, Mina Psichogiou (146065), Y. Young, C. Stephan, Chêne, G, Martin Fisher (300134), C. Lewden, A. D’Arminio Monforte, Ayayi, Sylvie, R. Zangerle, Young, J, S. De Wit, Laurence Meyer (130347), Bucher, Heiner, Antonella Castagna, Miró, José María, Geneviève Chêne, C. Sabin, Meyer, Laurence, Félix Gutierrez, Miro, José M, P. Morlat, P. Tookey, C. Torti, Gazzard, Brian, R. Paredes, Miro, José M., The Opportunistic Infections Project Team of the Collaboration of Observational HIV Epidemiological Research in Europe (COHERE) in EuroCoord (614233), J. M. Miro, V. Le Moing, I. Weller, Francois Raffi, A. Mocroft, C. Smit, Jim Young (252690), S. Ayayi, Grarup, J, Jesper Kjaer, Sharland, M, Brian Gazzard, M. Prins, J. Warszawski, A. Noguera Julian, M. Garrido, De Wit, S, F. de Wolf, H. Bucher, Muñoz, J, J. Miro, C. Thorne, O. Kirk, Francois Raffi (6269708), Stéphane De Wit, Jesper Grarup, Gutierrez, Félix, J. Kjaer, Kjaer, J, J. Munoz, Bucher, Heiner H.C., Ole Kirk, V. von Wyl, C. Leport, A. Scherrer, L. Galli, Opportunistic Infections Project Team of the Collaboration of Observational HIV Epidemiological Research in Europe (COHERE) in EuroCoord, Kjaer, Jesper, D. Costagliola, J. Sterne, Sophie Grabar, Opportunistic Infections Project Team of the Collaboration of Ob, P. Reiss, F. Dabis, Heiner Bucher (3510056), Meyer, L, A. Antoniadou, Furrer, Hansjakob, Jim Young, J. Ramos, J. Bohlius, A. Phillips, Hansjakob Furrer, Noguera Julian, Antoni, Sylvie Ayayi, Collaboration of Observational HIV Epidemiological Research Europe (COHERE), Castagna, A, Geneviève Chêne (252698), Ayayi, S, Obel, Niels, C. Colin, Bucher, H, F. Raffi, R. Teira, Jesper Kjaer (453100), Castagna, Antonella, Psichogiou, M, L. Meyer, N. Brockmeyer, A. Rauch, G. Chene, Miro, JM, Grabar, Sophie, M. Puoti, Kirk, O, Laurence Meyer, Reekie, Joanne ; https://orcid.org/, Muñoz, Josefa, B. Gazzard, N. Obel, M. M. Krause, J. Del Amo, Mina Psichogiou, L. Wittkop, M. Battegay, Grabar, S, Stéphane De Wit (262489), Brian Gazzard (4921), M. Fisher, Reiss, P, Gutierrez, F, S. Perez Hoyos, M. Dorrucci, Mike Sharland (258810), M. Paulsen, B. Ledergerber, Mike Sharland, Sharland, Mike, Psichogiou, Mina, C. Mussini, Félix Gutierrez (379459)   +181 more
core   +1 more source

Effects of Soluble CD4 on Simian Immunodeficiency Virus Infection of CD4-Positive and CD4-Negative Cells [PDF]

Journal of Virology, 1999
ABSTRACT A soluble form of the CD4 receptor (sCD4) can either enhance or inhibit the infection of cells by simian immunodeficiency virus (SIV) and human immunodeficiency virus. We investigated the basis for these varying effects by studying the entry of three SIV isolates into CD4-positive and CD4-negative cells expressing different chemokine
SCHENTEN D., MARCON, LUISA, KARLSSON G., PAROLIN, MARIA CRISTINA, KODAMA T., GERARD N., SODROSKI J.   +6 more
openaire   +3 more sources

Multiple Immune Abnormalities in a Patient with Idiopathic CD4+ T-Lymphocytopenia [PDF]

, 2009
Idiopathic CD4+ T-lymphocytopenia (ICL) is a new disease entity characterized by CD4+ T-lymphocyte depletion without evidence of HIV infection. We report a 27-year-old ICL patient with a long history of multiple immune abnormalities.
Tsukasaki, Kunihiro, Hiroyuki Moriuchi, Masahiko Okada, Masanori Yanai, Kamitamari, Akira, Kamihira, Shimeru, Yasuaki Yamada, Hiroo Hasegawa, Hasegawa, Hiroo, Akira Kamitamari, Yamada, Yasuaki, Yanagihara, Katsunori, Kazuto Tsuruda, Kunihiro Tsukasaki, Katsunori Yanagihara, Osamu Hano, Okada, Masahiko, Shimeru Kamihira, Yanai, Masanori, Hano, Osamu, Moriuchi, Hiroyuki, Tsuruda, Kazuto   +21 more
core   +1 more source

Imbalanced T-Cell Subsets May Facilitate the Occurrence of Osteonecrosis of the Femoral Head

Journal of Inflammation Research, 2022
Changjun Chen,1 Xin Zhao,1,2 Yue Luo,1 Bohua Li,1 Qianhao Li,1 Chengcheng Zhao,1 Yan Huang,3 Pengde Kang1 1Department of Orthopedics, West China Hospital, Sichuan University, Chengdu, People’s Republic of China; 2Department of Orthopedics, Shandong ...
Chen C, Zhao X, Luo Y, Li B, Li Q, Zhao C, Huang Y, Kang P   +7 more
doaj  

CD4+ and CD8+ Tumor-Infiltrating Lymphocytes (TILs) Biomarkers: Role in Predicting the Stadium and Prognosis of Cervical Cancer

Indonesian Journal of Cancer, 2022
Background: Tumor-infiltrating lymphocytes (TILs), mainly CD4+ and CD8 + T cells, have been extensively described in anti-tumor immunity, and knowledge of CD4+ and CD8+ T lymphocytes’ interplay in mediating the control of tumor growth exists.
Humairah Medina Liza Lubis , Rafa Nabila Haifa, Rizky Yusfasari, Muhammad Zikri Agung Ramadhan   +3 more
doaj   +1 more source

Effect of pembrolizumab on CD4+CD25+, CD4+LAP+ and CD4+TIM-3+ T cell subsets [PDF]

Clinical and Experimental Immunology, 2019
Summary Tumor immune evasion involves the expansion of avidly proliferating immunosuppressive cells and inhibition of effector T cell proliferation. Immune checkpoints (IC) block the activation pathways of tumor-reactive T cells. IC pathways are often exploited by tumor cells to evade immune destruction, and blocking these pathways ...
S M Toor, V Sasidharan Nair, G Pfister, E Elkord   +3 more
openaire   +2 more sources

CD4 expression decrease by antisense oligonucleotides. Inhibition of rat T CD4+ cell reactivity

, 2012
In previous studies, we have demonstrated the inhibition of CD4 expression in rat lymphocytes treated with phorbol myristate acetate (PMA) by antisense oligonucleotides (AS-ODNs) directed against the AUG start region of the cd4 gene.
Franch i Masferrer, Àngels, Ciudad i Gómez, Carlos Julián, Castellote i Bargalló, M. Cristina, Castell, Margarida, Noé Mata, Verónica, Rabanal i Tornero, Manel, Pelegrí i Gabaldà, Carme   +6 more
core   +1 more source