Hemodialysis Affects Phenotype and Proliferation of CD4-Positive T Lymphocytes [PDF]
CD4(+) T lymphocytes of patients with chronic kidney disease (CKD) are characterized by reduced levels of crucial surface antigens and changes in the cell cycle parameters. Recombinant human erythropoietin (rhEPO) normalizes their altered phenotype and proliferative capacity.
Alicja Dębska-Ślizień+5 more
semanticscholar +7 more sources
Characterization of the MRC OX40 antigen of activated CD4 positive T lymphocytes--a molecule related to nerve growth factor receptor. [PDF]
The antigen recognized by the monoclonal antibody (mAb) MRC OX40 is present on activated rat CD4 positive T lymphocytes but not other cells. cDNA clones were isolated from an expression library using the MRC OX40 mAb and the protein sequence for the OX40 antigen deduced. It contains a typical signal sequence and a single putative transmembrane sequence
Mallett, S, Fossum, S, Barclay, A
semanticscholar +6 more sources
CD4-Positive T Lymphocytes Provide a Neuroimmunological Link in the Control of Adult Hippocampal Neurogenesis [PDF]
Abstract Adult hippocampal neurogenesis occurs in an exceptional permissive microenvironment. Neuroimmunological mechanisms might be prominently involved in the endogenous homeostatic principles that control baseline levels of adult neurogenesis.
Armin Braun+13 more
semanticscholar +6 more sources
CD4-Positive and CD8-Positive Cytotoxic T Lymphocytes Contribute to Human Papillomavirus Type 16 E6 and E7 Responses [PDF]
ABSTRACTCytotoxic T-lymphocyte (CTL) responses to E6 and E7 were previously shown to be more commonly detectable in human papillomavirus type 16 (HPV-16)-positive women without squamous intraepithelial neoplasia (SIL) than in HPV-16-positive women with SIL (M. Nakagawa, D. P. Stites, S. Farhat, J. R. Sisler, B. Moss, F. Kong, A. B. Moscicki, and J.
Anna-Barbara Moscicki+4 more
semanticscholar +4 more sources
T1E28z CAR-expressing Autologous CD4-positive T Lymphocytes [PDF]
semanticscholar +3 more sources
Comparative evaluation of memory T cells in COVID-19 patients and the predictive role of CD4+CD8+ double positive T lymphocytes as a new marker [PDF]
BACKGROUND The COVID-19 pandemic has affected the entire world, posing a serious threat to human health. T cells play a critical role in the cellular immune response against viral infections. We aimed to reveal the relationship between T cell subsets and
Yasin Kalpakçı+8 more
openalex +2 more sources
Ivabradine Reduces Chemokine-Induced CD4-Positive Lymphocyte Migration [PDF]
Aims. Migration of CD4-positive lymphocytes into the vessel wall is a critical step in atherogenesis. Recent data suggest that ivabradine, a selective I(f)-channel blocker, reduces atherosclerotic plaque formation in apolipoprotein E-deficient mice ...
Thomas Walcher+6 more
doaj +4 more sources
This report describes induction of HIV-1 resistance and synthesis of resistance factors in immortal CD4-positive T lymphocytes. SupT1 cells were infected by NL4-3 attenuated by a defect in the vif gene through coculture with infected primary lymphocytes.
Malgorzata Simm+7 more
openalex +2 more sources
NY-ESO-1-specific CD4-positive T Lymphocytes [PDF]
A preparation of autologous CD4+ T-lymphocytes sensitized to cancer-testis antigen NY-ESO-1, with potential immunostimulating and antineoplastic activities.
openaire +2 more sources
LXR Activation Reduces Proinflammatory Cytokine Expression in Human CD4-Positive Lymphocytes [PDF]
Background— CD4-positive lymphocytes, the major T-cell population in human atheroma, mainly secrete Th-1-type proinflammatory cytokines, like interferon (IFN)γ, tumor necrosis factor (TNF)α, and interleukin (IL)-2, thus promoting atherogenesis.
Miriam Grüb+7 more
openaire +4 more sources