Hemodialysis affects phenotype and proliferation of CD4-positive T lymphocytes. [PDF]
J Clin Immunol, 2012 CD4(+) T lymphocytes of patients with chronic kidney disease (CKD) are characterized by reduced levels of crucial surface antigens and changes in the cell cycle parameters. Recombinant human erythropoietin (rhEPO) normalizes their altered phenotype and proliferative capacity.
Lisowska KA +5 more
europepmc +7 more sources
Decrease in CD4 and CD8 lymphocytes are predictors of severe clinical picture and unfavorable outcome of the disease in patients with COVID-19 [PDF]
Open MedicineThe main objective of this study was to investigate the association between CD4+ and CD8+ lymphocyte values and disease severity, need for oxygen therapy and disease outcomes.
Jovičić Biljana Popovska +11 more
doaj +2 more sources
Characterization of the MRC OX40 antigen of activated CD4 positive T lymphocytes--a molecule related to nerve growth factor receptor. [PDF]
The EMBO Journal, 1990 The antigen recognized by the monoclonal antibody (mAb) MRC OX40 is present on activated rat CD4 positive T lymphocytes but not other cells. cDNA clones were isolated from an expression library using the MRC OX40 mAb and the protein sequence for the OX40 antigen deduced. It contains a typical signal sequence and a single putative transmembrane sequence
Susan Mallett +2 more
openalex +5 more sources
Ivabradine Reduces Chemokine-Induced CD4-Positive Lymphocyte Migration [PDF]
Mediators of Inflammation, 2010 Aims. Migration of CD4-positive lymphocytes into the vessel wall is a critical step in atherogenesis. Recent data suggest that ivabradine, a selective I(f)-channel blocker, reduces atherosclerotic plaque formation in apolipoprotein E-deficient mice ...
Thomas Walcher +6 more
doaj +4 more sources
Lymphocyte immunophenotype in dogs with immune-mediated hematologic disease. [PDF]
PLoS ONEImmune-mediated hematologic diseases (IMHD) including immune-mediated hemolytic anemia (IMHA) and immune thrombocytopenia (ITP) can cause severe disease in dogs.
Shauna L Blois +2 more
doaj +2 more sources
CD4-Positive T Lymphocytes Provide a Neuroimmunological Link in the Control of Adult Hippocampal Neurogenesis [PDF]
The Journal of Immunology, 2009 Abstract Adult hippocampal neurogenesis occurs in an exceptional permissive microenvironment. Neuroimmunological mechanisms might be prominently involved in the endogenous homeostatic principles that control baseline levels of adult neurogenesis.
Susanne A. Wolf +7 more
openalex +5 more sources
CD4-Positive and CD8-Positive Cytotoxic T Lymphocytes Contribute to Human Papillomavirus Type 16 E6 and E7 Responses [PDF]
Clinical Diagnostic Laboratory Immunology, 1999 ABSTRACTCytotoxic T-lymphocyte (CTL) responses to E6 and E7 were previously shown to be more commonly detectable in human papillomavirus type 16 (HPV-16)-positive women without squamous intraepithelial neoplasia (SIL) than in HPV-16-positive women with SIL (M. Nakagawa, D. P. Stites, S. Farhat, J. R. Sisler, B. Moss, F. Kong, A. B. Moscicki, and J.
Mayumi Nakagawa +4 more
openalex +3 more sources
CD4+CD8+ Double-Positive T-Lymphocytes: Pitfalls
Turkish Journal of Hematology, 2020 İrfan Yavaşoğlu
doaj +2 more sources