Modified limiting dilution analysis (LDA) techniques were used to evaluate the mobilization of antigen-stimulated helper T lymphocytes (HTL) and cytotoxic T lymphocytes (CTL) following allogeneic heterotopic cardiac transplantation. These modified LDA techniques allow a quantitative comparison of T cells that have been stimulated by antigen in vivo ...
D. K. Bishop, J. Shelby, E. Eichwald
semanticscholar +3 more sources
CD8-positive T lymphocytes specific for murine cytomegalovirus immediate-early antigens mediate protective immunity [PDF]
We have shown in a murine model system for acute, lethal cytomegalovirus (CMV) disease in the immunocompromised natural host that control of virus multiplication in tissues, protection from virus-caused tissue destruction, and survival are mediated by ...
Reddehase, Matthias J. +4 more
core +2 more sources
Lifestyle of HIV seropositives patients and your association with CD4 positive t-lymphocytes counts
The purpose of this study was to evaluate the lifestyle of patients with Human Immunodeficiency Virus (HIV)and to associate it with CD4 positive T-lymphocytes counts. The convenience sample was composed by 111 subjects (68 males and 43 females, with mean
Mark Crosland Guimarães +3 more
doaj +2 more sources
CD4-helper-independent antiviral function of CD8-positive memory T lymphocytes derived from latently infected donors [PDF]
The ability of memory T lymphocytes derived from latently infected mice to control murine cytomegalovirus disease in the immunocompromised host was studied by adoptive transfer experiments.
Reddehase, Matthias J. +4 more
core +1 more source
Efficacious control of cytomegalovirus infection after long-term depletion of CD8+ T lymphocytes [PDF]
Although the relative contribution of different immune effector functions to clearing tissues of cytomegalovirus is controversial, the contribution of CD8+ T lymphocytes has generally been accepted as essential. In this report, we show that under certain
Pavic, Ivica +6 more
core +1 more source
The purpose is to study the shifts in the subpopulation composition of blood lymphocytes in patients with infectious corneal lesions, depending on the number of keratoplasties (KP) undergone by the patient.Material and methods.
V. V. Neroev +4 more
doaj +1 more source
Atypical CD3+ CD4(low) cell population in a boy with fatal EBV-infection [PDF]
A previously healthy 10-year-old Greek boy born to nonconsanguineous healthy parents developed progressive liver disease after acute infectious mononucleosis.
Krauss-Etschmann, Susanne +4 more
core +1 more source
Mice Deficient in Nucleoporin Nup210 Develop Peripheral T Cell Alterations
The nucleopore is an essential structure of the eukaryotic cell, regulating passage between the nucleus and cytoplasm. While individual functions of core nucleopore proteins have been identified, the role of other components, such as Nup210, are poorly ...
Annemarie van Nieuwenhuijze +19 more
doaj +1 more source
A ROLE FOR INTERLEUKIN 8 IN DIRECT REGULATION OF T CELL FUNCTIONAL ACTIVITY
CD3+T lymphocytes were isolated from normal donors by positive magnetic separation. Activation of the T cells with particles conjugated with antibodies to CD3, СD28 and СD2 molecules led to substantial increase in T cell production of interleukin-8 (IL-8)
M. E. Meniailo +7 more
doaj +1 more source
Understanding the slow depletion of memory CD4(+) T cells in HIV infection [PDF]
Background The asymptomatic phase of HIV infection is characterised by a slow decline of peripheral blood CD4(+) T cells. Why this decline is slow is not understood.
Nigel Klein +19 more
core +1 more source

