Results 131 to 140 of about 463,708 (346)

Evolution of replication efficiency following infection with a molecularly cloned feline immunodeficiency virus of low virulence [PDF]

, 2002
The development of an effective vaccine against human immunodeficiency virus is considered to be the most practicable means of controlling the advancing global AIDS epidemic.
Cannon, C., Dunsford, T.H., Hosie, M.J., Jarrett, O., Klein, D., Neil, J.C., Shimojima, M., Willett, B.J.   +7 more
core   +2 more sources

Oligoclonality of Rat Intestinal Intraepithelial T Lymphocytes: Overlapping TCR β-Chain Repertoires in the CD4 Single-Positive and CD4/CD8 Double-Positive Subsets [PDF]

, 1999
Lars Helgeland, Finn–Eirik Johansen, Jon O. Utgaard, John Torgils Vaage, Per Brandtzæg   +4 more
openalex   +1 more source

Analysis of differences in lymphocyte subsets and CD4+ T cells immune activation between re-detectable positive and non-re-detectable positive COVID-19 convalescent patients [PDF]

, 2022
Zhimin Huang, Guilian Li, Zhengrong Yang, Lin Zhou, Min Jiang, Hao Li, Yifan Zhong, Yixiang Jiang, Xiaohui Wang, Taiping He   +9 more
openalex   +1 more source

Tailoring Vascular‐Immune Homeostasis via Manganese‐DNA Complex‐Armed Immunogenic Extracellular Vesicles for Pancreatic Cancer Immunotherapy

Advanced Science, EarlyView.
This study demonstrates that Mn2⁺–tumor DNA complexes encapsulated in dendritic cell (DC)– derived immunogenic extracellular vesicles (EVDC@Mn‐DNA) act as a DC‐specific cGAS– STING activator. EVDC@Mn‐DNA treatment enhances intratumoral DC activation, improves tumor vascular function, promotes CD8⁺ T cell activity, and suppresses pancreatic tumor growth,
Xue Jiang, Lihuan Shang, Xiaochun Chen, Xiangzhan Kong, Xiaojuan Wang, Linjia Jiang, Huiying Zhao, Yafeng Zhu, Cheng Huang, Shiyi Deng, Rui Zhang, Minghui Wang, Haoming Lin, Ping‐Pui Wong   +13 more
wiley   +1 more source

Lymphocyte immunophenotype in dogs with immune-mediated hematologic disease.

PLoS ONE
Immune-mediated hematologic diseases (IMHD) including immune-mediated hemolytic anemia (IMHA) and immune thrombocytopenia (ITP) can cause severe disease in dogs.
Shauna L Blois, Benoît Y Cuq, Dorothee Bienzle   +2 more
doaj   +1 more source

CIITA‐driven MHC‐II positive tumor cells: Preventive vaccines and superior generators of antitumor CD4⁺ T lymphocytes for immunotherapy [PDF]

, 2010
Valeria Frangione, Lorenzo Mortara, Patrizia Castellani, Andrea De Lerma Barbaro, Roberto S. Accolla   +4 more
openalex   +1 more source

Differential expression of CXCR3 and CCR6 on CD4+ T-lymphocytes with distinct memory phenotypes characterizes tuberculosis-associated immune reconstitution inflammatory syndrome

Scientific Reports, 2019
Immune reconstitution inflammatory syndrome (IRIS) occurs in up to 40% of individuals co-infected with pulmonary tuberculosis (PTB) and HIV, primarily upon antiretroviral therapy (ART) initiation.
P. S. Silveira-Mattos, G. Narendran, Kevan M Akrami, K. Fukutani, S. Anbalagan, Kaustuv Nayak, S. Subramanyam, Rajasekaran Subramani, Caian L. Vinhaes, Deivide Oliveira-de Souza, L. Antonelli, Kumar Satagopan, B. O. Porter, A. Sher, S. Swaminathan, I. Sereti, B. Andrade   +16 more
semanticscholar   +1 more source

PD‐1 Inhibits CD4+ TRM‐Mediated cDC1 Mobilization via Suppressing JAML in Human NSCLC

Advanced Science, EarlyView.
CD4+ tissue‐resident memory T cells (TRMs) in non‐small cell lung cancer recruit conventional type 1 dendritic cells via XCL1‐XCR1 signaling, orchestrating antitumor immunity. The costimulatory molecule JAML is essential for this process. PD‐1 blockade restores JAML expression and cDC1 mobilization, while JAML agonists synergize with anti‐PD‐1 therapy,
Zheyu Shao, Qinyuan Liu, Zhongwei Xin, Zhiyao Zhou, Mingjie Lin, Di Chen, Zhixing Hao, Yongyuan Chen, Wenxuan Wu, Shuyang Zhang, Xiaoke Chen, Xia Xu, Jinfan Li, Wei Lin, Yuhao Lu, Dang Wu, Pin Wu   +16 more
wiley   +1 more source

In Reply to: CD4+CD8+ Double-Positive T-Lymphocytes: Pitfalls

Turkish Journal of Hematology, 2020
Miguel Santiago Gonzalez-Mancera, John Mario Gonzalez   +1 more
doaj   +1 more source

Increased CD4+ T cell lineage commitment determined by CpG methylation correlates with better prognosis in urinary bladder cancer patients

Clinical Epigenetics, 2018
Background Urinary bladder cancer is a common malignancy worldwide. Environmental factors and chronic inflammation are correlated with the disease risk.
Emma Ahlén Bergman, Ciputra Adijaya Hartana, Markus Johansson, Ludvig B. Linton, Sofia Berglund, Martin Hyllienmark, Christian Lundgren, Benny Holmström, Karin Palmqvist, Johan Hansson, Farhood Alamdari, Ylva Huge, Firas Aljabery, Katrine Riklund, Malin E. Winerdal, David Krantz, A. Ali Zirakzadeh, Per Marits, Louise K. Sjöholm, Amir Sherif, Ola Winqvist   +20 more
doaj   +1 more source