Results 241 to 250 of about 314,352 (325)

Development of Ulcerative Colitis in a Patient With Human Immunodeficiency Virus. [PDF]

Case Rep Gastrointest Med
Miranda CJ, Ali MH, Hossein-Javaheri N, Azad F, Singh MA, Rana NK, Ravish NA, Mahl TC.   +7 more
europepmc   +1 more source

Pyroptosis‐Inducing Platinum(IV) Prodrugs via GSDME Pathway for Chemoimmunotherapy and Metastasis Inhibition in Triple‐Negative Breast Cancer

Advanced Science, EarlyView.
Three PtIV prodrugs MRP, DRP, and HRP are designed to induce pyroptosis in low GSDME‐expressing tumor cells via the Caspase‐3/GSDME pathway. By relaxing chromatin and reactivating GSDME, HRP can effectively induce pyroptosis, enhance pro‐inflammatory cytokine production, and exhibit potent antitumor effects.
Xinda Yang, Chuansheng Xu, Youliang Zeng, Chunhui Wang, Yan Gao, Jie Ding, Sirui Chen, Yuheng Pan, Xin Zhang, Zongwan Mao, Shuo Shi   +10 more
wiley   +1 more source

Effect of estradiol valerate on humoral immune function in BALB/c mice after total hysterectomy. [PDF]

Braz J Med Biol Res
Chang P, Huang H, Huang P, Yi H, Zhong W, Yang Z.   +5 more
europepmc   +1 more source

Prevalence of Enteric Parasites in HIV-Positive Patients with Diarrhoea and Their Correlation with CD4+ T-Lymphocyte Counts

, 2016
Dr.Saswati Chattopadhyay, Santanu Pramanik, Asraful Islam, Indrajit Gupta, Paulami Ghosh, Gadadhar Mitra   +5 more
openalex   +1 more source

Nanomaterials Trigger Functional Anti‐Tumoral Responses in Primary Human Immune Cells

Advanced Science, EarlyView.
Nanoparticles are used to improve immunomodulatory therapies, but the impact of drug‐free nanomaterials on the immune system remains unknown. Screening common biomedical nanoparticles (NPs) reveals that PLGA NPs enhanced NK cell anti‐tumoral activity and transcriptional activation in human NK and pan T cells.
Vincent Mittelheisser, Olivier Lefebvre, Mainak Banerjee, Shayamita Ghosh, Amandine Dupas, Marie‐Charlotte Diringer, Juliette Blumberger, Louis Bochler, Sébastien Harlepp, Annabel Larnicol, Angélique Pichot, Tristan Stemmelen, Anne Molitor, Chloé Moritz, Christine Carapito, Raphaël Carapito, Loïc J. Charbonnière, François Lux, Olivier Tillement, Jacky G. Goetz, Alexandre Detappe   +20 more
wiley   +1 more source

Changes in T-lymphocyte subpopulations in patients with colorectal cancer before and after acupoint catgut embedding acupuncture observation. [PDF]

Open Life Sci
Yang C, Bao J, Li D.
europepmc   +1 more source

The effect of FK 506 on peripheral blood T-lymphocyte subsets in orthotopic liver transplant patients [PDF]

, 1991
Hayashi, S, Iwaki, Y, Kobayashi, M, Konno, A, Noguchi, K, Ogura, K, Selby, R, Starzl, TE, Takenaka, T, Terasawa, K, Ujike, Y, Warty, V, Yagihashi, A, Yoshida, Y   +13 more
core  

Rapid‐Turnaround Co‐Administration of mRNA‐Based MHC‐I and MHC‐II‐Restricted Neoantigens Enhances Immune Responses of Antigen‐Specific CD8+ T Cells and Anti‐Cancer Efficacy in Colorectal Cancer

Advanced Science, EarlyView.
Co‐administration with MHC class I‐ and II‐restricted neoantigens encoding mRNA‐based personalized cancer vaccines in a mouse CRC model can induce antigen‐specific immune responses and anti‐cancer effects. Notably, vaccination at an early stage of cancer development can have potent anti‐cancer effects. Furthermore, combining mRNA with immune checkpoint
Seongje Cho, Woori Kwak, Hyunho Yoon, Jisun Lee, Seonghyun Lee, Hyo‐Jung Park, Sohee Jo, Yu‐Sun Lee, Yu‐Jeong Seo, Youngran Cho, Seo‐Hyeon Bae, Subin Yoon, Gahyun Roh, Dahyeon Ha, Ayoung Oh, Eun‐Jin Choi, Soo‐Yeon Lee, Huijeong Choi, Jungmin Kim, Yeeun Lee, Sowon Lee, Sang‐In Park, Dae‐Keun Kim, Jun Chang, Ki Tae Kim, Kwoneel Kim, Jae‐Hwan Nam   +26 more
wiley   +1 more source

RUNX1/SLAMF3 Axis Drives Immunosuppression to Contribute to Colorectal Cancer Liver Metastasis by Blocking Phagocytosis and Depleting C1QC+ Tumor‐Associated Macrophages

Advanced Science, EarlyView.
This study identifies the RUNX1/SLAMF3 axis as a key driver of colorectal cancer liver metastasis (CRLM). SLAMF3 suppresses macrophage phagocytosis and depletes C1QC⁺ tumor‐associated macrophages, promoting an immunosuppressive microenvironment. Targeting this axis restores macrophage and CD8⁺ T cell activity and reduces metastasis.
Yinheng Luo, Xiaoli Jin, Lan Huang, Dejia Zeng, Nan Zhang, Shiyu Tang, Shu Luo, Samina Ejaz Syed, Ruiwu Dai, Qiu Li, Shufang Liang   +10 more
wiley   +1 more source

Enhancing T-cell response with monoclonal antibodies and chemotherapy in advanced gastric cancer. [PDF]

World J Gastrointest Oncol
Pires AC, Uson Junior PLS.
europepmc   +1 more source