Results 241 to 250 of about 463,708 (346)

Targeting IL27RA Enhances Immunotherapy in Triple‐Negative Breast Cancer by Modulating Tumor Cells and the Tumor Microenvironment

Advanced Science, EarlyView.
IL27RA upregulation drives immune evasion in TNBC by suppressing MHC‐I expression and reprogramming T/NK‐cell states, establishing an immune‐excluded tumor phenotype. Targeting this epithelial‐intrinsic IL27RA–PI3K/AKT axis offers a promising strategy to overcome immunotherapy resistance.
Jiachi Xu, Qian Long, Meirong Zhou, Qitong Chen, Jing Peng, Qingchun Liang, Danhua Zhang, Hui Zhou, Wenjun Yi   +8 more
wiley   +1 more source

Expression and prognostic value of FKBP51 in Hodgkin lymphoma. [PDF]

Front Immunol
Varricchio S, Romano S, Russo D, Travaglino A, Cappiello R, Cervasio M, Ilardi G, Marrone L, Pane F, Picardi M, Persico M, Vigliar E, Acanfora G, Romano MF, Mascolo M.   +14 more
europepmc   +1 more source

Increase of peripheral CXCR3 positive T lymphocytes upon treatment of RA patients with TNF-alpha inhibitors.

Rheumatology, 2005
D. Aeberli, M. Seitz, P. Jüni, P. Villiger   +3 more
semanticscholar   +1 more source

Core Fucosylation Represses SMURF1‐Dependent Degradation of CD47 to Promote Tumor Immune Evasion

Advanced Science, EarlyView.
FUT8‐mediated core fucosylation of CD47 at N111 blocks SMURF1 binding and reduces CD47 ubiquitination and degradation. Blocking N111 glycosylation reduces CD47 expression and promotes macrophage phagocytosis of tumor cells. Furthermore, ablating CD47 core fucosylation boosts CD103+ dendritic cells (DCs) infiltration, increases natural killer (NK) cell ...
Yuting Cao, Siyuan Chai, Mingyang Li, Xiaoming Chen, Jiating Hu, Bingyi Lin, Liming Wu, Wen Yi, Qiang Zhu   +8 more
wiley   +1 more source

Assessment of feline peripheral blood lymphocyte subpopulations and CD18 expression pattern by flow cytometry. [PDF]

Braz J Vet Med
Lindiman P, Sánchez Solé R, Pessina P, Mosquillo MF.   +3 more
europepmc   +1 more source

Kinetics of the local cellular response in the gastric lymph of immune and susceptible sheep to infection with Teladorsagia circumcincta [PDF]

, 2009
Halliday, A. M., Morrison, W. I., Smith, W. D.   +2 more
core   +1 more source

CD4dullCD8bright double-positive T-lymphocytes have a phenotype of granzyme Bpos CD8pos memory T-lymphocytes.

Nephrology, Dialysis and Transplantation, 1999
R. Rentenaar, Peter C. Wever, F. Diepen, P. Schellekens, Pauline M. E. Wertheim, I. J. T. Berge   +5 more
semanticscholar   +1 more source

Depletion of the RNA‐Editing Enzyme ADAR1 Invigorates the Antitumor Immunity of NK Cells

Advanced Science, EarlyView.
ADAR1 is upregulated in NK cells from melanoma patients, impairing their function. Its loss enhances NK cell tumor infiltration and cytotoxicity in vitro and in vivo. Mechanistically, ADAR1 deficiency destabilizes CD38 mRNA to reduce its expression, thereby increasing NK cell mobility and killing, which nominates it as a therapeutic target for NK cell ...
Shuhan Chen, Di Lu, Rukang Liang, Weikeng Tan, Erming Zhao, Sihuang Wu, Xintong Li, Yulong Song, Miaojian Wan, Xiaoyuan Xie, Qi Zhang, Qiuli Liu   +11 more
wiley   +1 more source

Indolent T-cell lymphoma of the gastrointestinal tract coexisting with gastric signet-ring cell carcinoma: A case report and review of literature. [PDF]

World J Gastroenterol
Chen X, Bo JQ, Gao XX, Zhang SX, Li J, Wang H, Yang MY, Guo QQ, Xiu B, Zeng Y.   +9 more
europepmc   +1 more source

PHENOTYPIC T-CELL CHANGES IN THORACIC TRANSPLANT RECIPIENTS IMMUNOSUPPRESSED WITH FK506 [PDF]

, 1991
ARMITAGE, J, DUQUESNOY, R, GRIFFITH, B, KAUFMAN, C, KEENAN, R, KORMOS, R, STARZL, T, YOUSEM, S, ZEEVI, A, ZERBE, T   +9 more
core