Results 251 to 260 of about 14,938,680 (293)

CD4-positive T lymphocytes are required for the generation of the primary but not the secondary CD8-positive cytolytic T lymphocyte response to herpes simplex virus in C57BL/6 mice

Cellular Immunology, 1991
To understand the cellular basis for recovery from HSV infection, it is critical to identify functional interactions between HSV-specific T lymphocyte subpopulations involved in the generation of the optimal response. To this end, the requirement for CD4+ (L3T4+) T lymphocytes in the development of the primary and secondary CD8+ (Lyt-2+) cytolytic T ...
S R, Jennings, R H, Bonneau, P M, Smith, R M, Wolcott, R, Chervenak   +4 more
openaire   +2 more sources

Activated CD4-positive T-lymphocytes and impaired cell-mediated immunity in patients with carcinoma of the urinary bladder with schistosomiasis

Cancer, 1990
Patients with schistosomiasis of the urinary bladder (SB) associated with carcinoma of the bladder (SCB) or carcinoma of the prostate (SCP) have a variety of immunologic abnormalities, including the presence of HLA-DR+ and interleukin-2 receptor-positive (IL-2R+) T-lymphocytes in circulating blood.
S, Raziuddin, S, Shetty, A, Ibrahim, K, Patil   +3 more
openaire   +2 more sources

HELPER T LYMPHOCYTE UNRESPONSIVENESS TO CARDIAC ALLOGRAFTS FOLLOWING TRANSIENT DEPLETION OF CD4-POSITIVE CELLS

Transplantation, 1994
Initial treatment of heterotopic cardiac transplant recipients with anti-CD4 mAb promotes long-term (> 60 days) allograft survival. We have used modified limiting dilution analysis to quantitate donor alloantigen-reactive helper T lymphocytes (HTL) and CTL in mice bearing long-term cardiac allografts.
D K, Bishop, W, Li, S Y, Chan, R D, Ensley, J, Shelby, E J, Eichwald   +5 more
openaire   +2 more sources

Removal of Autologous Activated CD4 Positive T Lymphocytes Also Result in Increased Colony-Forming Units (CFUs) in Patients with Myelodysplastic Syndromes.

Blood, 2009
Abstract Abstract 4862 Autologous activated CD4+ T lymphocytes (CD4+/CCR5+ double positive cells) in BMNC of 29 MDS patients were depleted or plused in in vitro cultures. That cultures with removed CD4+/CCR5+ cells exhibited significantly increased CFU generation.
Feng Xu
exaly   +2 more sources

Profiles of cytokines produced by CD4-positive T lymphocytes stimulated by anti-CD3 antibody in patients with chronic hepatitis C

Journal of Gastroenterology, 1998
Helper T cells (Th) are classified as type 1 (Th1) and type 2 (Th2) according to the cytokines they produce; interferon-gamma is produced by Th1, and interleukin-4 by Th2. We counted the circulating CD4-positive Th cells that produce interferon-gamma or interleukin-4 with an enzyme-linked immunospot assay.
K, Kobayashi, M, Ishii, T, Igarashi, T, Satoh, Y, Miyazaki, Y, Yajima, K, Ukai, H, Suzuki, A, Kanno, Y, Ueno, T, Miura, T, Toyota   +11 more
openaire   +2 more sources

Antigens of activated rat T lymphocytes including a molecule of 50,000 Mr detected only on CD4 positive T blasts

Molecular Immunology, 1987
Mouse monoclonal antibodies (MAbs) have been prepared against rat T cell blasts. One MAb called MRC OX-40 recognized an antigen that differed from any previously described in that its expression was detected only on T blasts that also expressed the CD4 antigen.
D J, Paterson, W A, Jefferies, J R, Green, M R, Brandon, P, Corthesy, M, Puklavec, A F, Williams   +6 more
openaire   +2 more sources

A Review of CD4 Positive T Lymphocytes Counts among HIV Positive Patients Attending a Nigerian Teaching Hospital

British Microbiology Research Journal, 2015
Aims and Objectives: To determine the baseline CD4 positive T lymphocytes count of HIV/AIDS treatment naive adults clients presenting for the first time treatment in Benue State University Teaching Hospital. Subjects and Methods: A total of 700 subjects age between 18 years to 70 years, were recruited for the study, comprising 600 HIV sero-positive ...
Nwadioha, S. I, Odimayo, M. S, Jombo, G. T. A, Prince, E. O. Nwokedi, Atef, M   +4 more
openaire   +2 more sources

Quantification of CD4-positive T lymphocytes

1995
Abstract Introduction The central lesion in HIV-induced immunodeficiency is the functional and numerical decrease in the CD4-positive population of T lymphocytes. Progressive loss of this key lymphoid population is associated with an increasing range and severity of cellular immunodeficiency and predisposition to ...
openaire   +1 more source

HLA‐DQ allele‐restricted activation of nitroso sulfamethoxazole‐specific CD4‐positive T lymphocytes from patients with cystic fibrosis

Clinical & Experimental Allergy, 2015
SummaryBackgroundFor certain HLA allele‐associated drug hypersensitivity reactions, the parent drug has been shown to associate directly with the risk allele. In other forms of hypersensitivity, HLA risk alleles have not been identified and T cells are activated in an allele unrestricted manner.
M O, Ogese, K, Saide, L, Faulkner, P, Whitaker, D, Peckham, A, Alfirevic, D M, Baker, A, Sette, M, Pirmohamed, B K, Park, D J, Naisbitt   +10 more
openaire   +2 more sources

Circulatory CD4-Positive T-Lymphocyte Imbalance Mediated by Homocysteine-Induced AIM2 and NLRP1 Inflammasome Upregulation and Activation Is Associated with Human Abdominal Aortic Aneurysm

Journal of Vascular Research, 2020
<b><i>Introduction:</i></b> CD4-positive T lymphocytes (CD4 cells) play a significant role in human abdominal aortic aneurysm (AAA). However, we know little about the role of the different CD4 subtypes. <b><i>Objective:</i></b> We aimed to discover the circulatory CD4 phenotypic marker profile and the ...
Hao, Wang, Guodong, Wei, Shuai, Cheng, Ding, Wang, Ju, Ma, Shijie, Xin   +5 more
openaire   +2 more sources