Results 251 to 260 of about 15,816,019 (291)

Recombinant Human Erythropoietin Treatment of Chronic Renal Failure Patients Normalizes Altered Phenotype and Proliferation of CD4‐positive T Lymphocytes

Artificial Organs, 2010
AbstractPatients with chronic renal failure (CRF) receive recombinant human erythropoietin (rhEPO) for the correction of anemia. However, rhEPO also has an immunomodulatory effect. Detailed changes of phenotype and function of CD4+ T lymphocytes in CRF patients receiving rhEPO have not been reported yet; their study may bring insight into understanding
Katarzyna A, Lisowska, Alicja, Debska-Slizien, Monika, Radzka, Jacek M, Witkowski, Boleslaw, Rutkowski, Ewa, Bryl   +5 more
openaire   +3 more sources

Profiles of cytokines produced by CD4-positive T lymphocytes stimulated by anti-CD3 antibody in patients with chronic hepatitis C

Journal of Gastroenterology, 1998
Helper T cells (Th) are classified as type 1 (Th1) and type 2 (Th2) according to the cytokines they produce; interferon-gamma is produced by Th1, and interleukin-4 by Th2. We counted the circulating CD4-positive Th cells that produce interferon-gamma or interleukin-4 with an enzyme-linked immunospot assay.
K, Kobayashi, M, Ishii, T, Igarashi, T, Satoh, Y, Miyazaki, Y, Yajima, K, Ukai, H, Suzuki, A, Kanno, Y, Ueno, T, Miura, T, Toyota   +11 more
openaire   +2 more sources

Antigens of activated rat T lymphocytes including a molecule of 50,000 Mr detected only on CD4 positive T blasts

Molecular Immunology, 1987
Mouse monoclonal antibodies (MAbs) have been prepared against rat T cell blasts. One MAb called MRC OX-40 recognized an antigen that differed from any previously described in that its expression was detected only on T blasts that also expressed the CD4 antigen.
D J, Paterson, W A, Jefferies, J R, Green, M R, Brandon, P, Corthesy, M, Puklavec, A F, Williams   +6 more
openaire   +2 more sources

A Review of CD4 Positive T Lymphocytes Counts among HIV Positive Patients Attending a Nigerian Teaching Hospital

British Microbiology Research Journal, 2015
Aims and Objectives: To determine the baseline CD4 positive T lymphocytes count of HIV/AIDS treatment naive adults clients presenting for the first time treatment in Benue State University Teaching Hospital. Subjects and Methods: A total of 700 subjects age between 18 years to 70 years, were recruited for the study, comprising 600 HIV sero-positive ...
Nwadioha, S. I, Odimayo, M. S, Jombo, G. T. A, Prince, E. O. Nwokedi, Atef, M   +4 more
openaire   +2 more sources

Quantification of CD4-positive T lymphocytes

1995
Abstract Introduction The central lesion in HIV-induced immunodeficiency is the functional and numerical decrease in the CD4-positive population of T lymphocytes. Progressive loss of this key lymphoid population is associated with an increasing range and severity of cellular immunodeficiency and predisposition to ...
openaire   +1 more source

Modeling Changes in CD4-Positive T-Lymphocyte Counts After the Start of Highly Active Antiretroviral Therapy and the Relation With Risk of Opportunistic Infections: The Aquitaine Cohort, 1996-1997.

American Journal of Epidemiology, 2001
Abstract After initiation of a treatment for human immunodeficiency virus type 1 infection containing a protease inhibitor, immune restoration associated with increases in CD4-positive (CD4+) T lymphocyte count may be delayed. In a sample of patients who had been prescribed protease inhibitors for the first time, the authors tested to ...
François Dabis, Hélène Jacqmin-Gadda, D Lacoste   +2 more
exaly   +3 more sources

HLA‐DQ allele‐restricted activation of nitroso sulfamethoxazole‐specific CD4‐positive T lymphocytes from patients with cystic fibrosis

Clinical & Experimental Allergy, 2015
SummaryBackgroundFor certain HLA allele‐associated drug hypersensitivity reactions, the parent drug has been shown to associate directly with the risk allele. In other forms of hypersensitivity, HLA risk alleles have not been identified and T cells are activated in an allele unrestricted manner.
M O, Ogese, K, Saide, L, Faulkner, P, Whitaker, D, Peckham, A, Alfirevic, D M, Baker, A, Sette, M, Pirmohamed, B K, Park, D J, Naisbitt   +10 more
openaire   +2 more sources

Circulatory CD4-Positive T-Lymphocyte Imbalance Mediated by Homocysteine-Induced AIM2 and NLRP1 Inflammasome Upregulation and Activation Is Associated with Human Abdominal Aortic Aneurysm

Journal of Vascular Research, 2020
<b><i>Introduction:</i></b> CD4-positive T lymphocytes (CD4 cells) play a significant role in human abdominal aortic aneurysm (AAA). However, we know little about the role of the different CD4 subtypes. <b><i>Objective:</i></b> We aimed to discover the circulatory CD4 phenotypic marker profile and the ...
Hao, Wang, Guodong, Wei, Shuai, Cheng, Ding, Wang, Ju, Ma, Shijie, Xin   +5 more
openaire   +2 more sources

MOBILIZATION OF T LYMPHOCYTES FOLLOWING CARDIAC TRANSPLANTATION

Transplantation, 1992
Modified limiting dilution analysis (LDA) techniques were used to evaluate the mobilization of antigen-stimulated helper T lymphocytes (HTL) and cytotoxic T lymphocytes (CTL) following allogeneic heterotopic cardiac transplantation. These modified LDA techniques allow a quantitative comparison of T cells that have been stimulated by antigen in vivo ...
D K, Bishop, J, Shelby, E J, Eichwald
openaire   +2 more sources

Resistance of CD4-positive T lymphocytes to etoposide-induced apoptosis mediated by upregulation of Bcl-xL expression in patients with HTLV-I-associated myelopathy

Journal of Neuroimmunology, 2001
Human T-lymphotropic virus type I (HTLV-I)-associated myelopathy (HAM) is characterized by chronic inflammation of the spinal cord. The exact mechanisms that enhance the development of chronic myelopathy remain to be determined. One such mechanism could be an altered response of peripheral blood CD4(+) T lymphocytes to apoptotic stimuli.
S, Hamasaki, T, Nakamura, T, Furuya, A, Kawakami, K, Ichinose, T, Nakashima, Y, Nishiura, S, Shirabe, K, Eguchi   +8 more
openaire   +2 more sources