Results 251 to 260 of about 347,385 (305)

Mental stimulation increases circulating CD4-positive T lymphocytes: a preliminary study

Cognitive Brain Research, 2001
To stimulate the dorsolateral frontal cortex, 12 healthy, adult, human females played contract bridge for 1.5 h between initial and final blood sample collections. Flow cytometric analyses of samples, performed in triplicate, showed a significant increase in CD4-positive T lymphocytes.
M C, Diamond, J, Weidner, P, Schow, S, Grell, M, Everett   +4 more
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CD4-POSITIVE HELPER T LYMPHOCYTES MEDIATE MOUSE CARDIAC ALLOGRAFT REJECTION INDEPENDENT OF DONOR ALLOANTIGEN SPECIFIC CYTOTOXIC T LYMPHOCYTES

Transplantation, 1993
Mouse heterotopic cardiac allograft recipients were depleted of CD4+ or CD8+ T lymphocytes in vivo to assess cellular requirements for graft infiltration, tissue damage, and acute allograft rejection. Modified limiting dilution analysis was employed to quantitate IL-2-producing Th lymphocytes (HTL) and CTL infiltrating the graft.
D K, Bishop, S, Chan, W, Li, R D, Ensley, S, Xu, E J, Eichwald   +5 more
openaire   +2 more sources

The Immunomodulatory Role of CD4-Positive Cytotoxic T-lymphocytes in Health and Disease

International Reviews of Immunology, 1999
Among the CD4-positive (CD4+) T-lymphocytes a population exists which expresses cytolytic activity. These 'killer' cells belong to the T helper type 1 (Th1) subset and if activated, express Fas-ligand (FasL) which induces apoptosis in Fas-positive target cells. The major targets of these CD4+ cytotoxic T-lymphocytes (CTL) are cells of the immune system,
S, Hahn, P, Erb
openaire   +2 more sources

Proteome database of unsensitized CD4 positive T lymphocytes in T cell receptor transgenic mice

ELECTROPHORESIS, 2003
AbstractWe established a two‐dimensional electrophoresis (2‐DE) mapping database of splenic CD4 T cells prepared from I‐Ad‐restricted ovalbumin (OVA)323‐339 specific T cell receptor (TCR) transgenic mice (OVA23‐3). First we examined the purification of CD4 T cells and found that the high purity of cells produced more accurate protein maps.
Tomohiro, Kaji, Satoshi, Hachimura, Shuichi, Kaminogawa   +2 more
openaire   +2 more sources

Decrease of CD4-positive T Lymphocytes in Workers Exposed to Benzidine and Beta-naphthylamine

Archives of Environmental Health: An International Journal, 1993
T lymphocyte subpopulations (CD4+, CD8+, and CD3+ cells), Leu 11a-(CD16) positive lymphocytes, and total lymphocytes in peripheral blood in 52 male dyestuff workers were analyzed to determine the effects of benzidine and beta-naphthylamine on the human immune system.
S, Araki, T, Tanigawa, S, Ishizu, N, Minato   +3 more
openaire   +2 more sources

CD4-Positive T-Lymphocytes Infiltrate the Bronchial Mucosa of Patients with Sjögren's Syndrome

American Journal of Respiratory and Critical Care Medicine, 1997
To investigate the degree and the type of inflammation in the bronchial mucosa in patients with Sjögren's syndrome, we examined lobar bronchial biopsies obtained from 10 patients with Sjögren's syndrome (six with primary and four with secondary) and eight control subjects.
Papiris SA, SAETTA, MARINA, TURATO, GRAZIELLA, La Corte R, Trevisani L, Mapp CE, MAESTRELLI, PIERO, Fabbri LM, Potena A.   +8 more
openaire   +5 more sources

HELPER T LYMPHOCYTE UNRESPONSIVENESS TO CARDIAC ALLOGRAFTS FOLLOWING TRANSIENT DEPLETION OF CD4-POSITIVE CELLS

Transplantation, 1994
Initial treatment of heterotopic cardiac transplant recipients with anti-CD4 mAb promotes long-term (> 60 days) allograft survival. We have used modified limiting dilution analysis to quantitate donor alloantigen-reactive helper T lymphocytes (HTL) and CTL in mice bearing long-term cardiac allografts.
D K, Bishop, W, Li, S Y, Chan, R D, Ensley, J, Shelby, E J, Eichwald   +5 more
openaire   +2 more sources

Recombinant Human Erythropoietin Treatment of Chronic Renal Failure Patients Normalizes Altered Phenotype and Proliferation of CD4‐positive T Lymphocytes

Artificial Organs, 2010
AbstractPatients with chronic renal failure (CRF) receive recombinant human erythropoietin (rhEPO) for the correction of anemia. However, rhEPO also has an immunomodulatory effect. Detailed changes of phenotype and function of CD4+ T lymphocytes in CRF patients receiving rhEPO have not been reported yet; their study may bring insight into understanding
Katarzyna A, Lisowska, Alicja, Debska-Slizien, Monika, Radzka, Jacek M, Witkowski, Boleslaw, Rutkowski, Ewa, Bryl   +5 more
openaire   +3 more sources

HLA‐DQ allele‐restricted activation of nitroso sulfamethoxazole‐specific CD4‐positive T lymphocytes from patients with cystic fibrosis

Clinical & Experimental Allergy, 2015
SummaryBackgroundFor certain HLA allele‐associated drug hypersensitivity reactions, the parent drug has been shown to associate directly with the risk allele. In other forms of hypersensitivity, HLA risk alleles have not been identified and T cells are activated in an allele unrestricted manner.
M O, Ogese, K, Saide, L, Faulkner, P, Whitaker, D, Peckham, A, Alfirevic, D M, Baker, A, Sette, M, Pirmohamed, B K, Park, D J, Naisbitt   +10 more
openaire   +2 more sources