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CD4-positive T-lymphocytes infiltrate the bronchial mucosa of patients with Sjögren's syndrome.
American Journal of Respiratory and Critical Care Medicine, 1997Abstract To investigate the degree and the type of inflammation in the bronchial mucosa in patients with Sjögren's syndrome, we examined lobar bronchial biopsies obtained from 10 patients with Sjögren's syndrome (six with primary and four with secondary) and eight control subjects.
S. Papiris +8 more
semanticscholar +5 more sources
Cellular Immunology, 1991
To understand the cellular basis for recovery from HSV infection, it is critical to identify functional interactions between HSV-specific T lymphocyte subpopulations involved in the generation of the optimal response. To this end, the requirement for CD4+ (L3T4+) T lymphocytes in the development of the primary and secondary CD8+ (Lyt-2+) cytolytic T ...
S. Jennings +4 more
semanticscholar +3 more sources
To understand the cellular basis for recovery from HSV infection, it is critical to identify functional interactions between HSV-specific T lymphocyte subpopulations involved in the generation of the optimal response. To this end, the requirement for CD4+ (L3T4+) T lymphocytes in the development of the primary and secondary CD8+ (Lyt-2+) cytolytic T ...
S. Jennings +4 more
semanticscholar +3 more sources
Mental stimulation increases circulating CD4-positive T lymphocytes: a preliminary study.
Cognitive Brain Research, 2001To stimulate the dorsolateral frontal cortex, 12 healthy, adult, human females played contract bridge for 1.5 h between initial and final blood sample collections. Flow cytometric analyses of samples, performed in triplicate, showed a significant increase in CD4-positive T lymphocytes.
M. Diamond +4 more
semanticscholar +3 more sources
Decrease of CD4-positive T lymphocytes in workers exposed to benzidine and beta-naphthylamine.
Archives of Environmental Health: An International Journal, 1993T lymphocyte subpopulations (CD4+, CD8+, and CD3+ cells), Leu 11a-(CD16) positive lymphocytes, and total lymphocytes in peripheral blood in 52 male dyestuff workers were analyzed to determine the effects of benzidine and beta-naphthylamine on the human immune system.
S. Araki +3 more
semanticscholar +3 more sources
Artificial Organs, 2010
AbstractPatients with chronic renal failure (CRF) receive recombinant human erythropoietin (rhEPO) for the correction of anemia. However, rhEPO also has an immunomodulatory effect. Detailed changes of phenotype and function of CD4+ T lymphocytes in CRF patients receiving rhEPO have not been reported yet; their study may bring insight into understanding
Katarzyna A Lisowska +2 more
exaly +5 more sources
AbstractPatients with chronic renal failure (CRF) receive recombinant human erythropoietin (rhEPO) for the correction of anemia. However, rhEPO also has an immunomodulatory effect. Detailed changes of phenotype and function of CD4+ T lymphocytes in CRF patients receiving rhEPO have not been reported yet; their study may bring insight into understanding
Katarzyna A Lisowska +2 more
exaly +5 more sources
The Immunomodulatory Role of CD4-Positive Cytotoxic T-lymphocytes in Health and Disease
International Reviews of Immunology, 1999Among the CD4-positive (CD4+) T-lymphocytes a population exists which expresses cytolytic activity. These 'killer' cells belong to the T helper type 1 (Th1) subset and if activated, express Fas-ligand (FasL) which induces apoptosis in Fas-positive target cells. The major targets of these CD4+ cytotoxic T-lymphocytes (CTL) are cells of the immune system,
Sinuhe Hahn, Peter Erb
exaly +5 more sources
Journal of Gastroenterology, 1998
Helper T cells (Th) are classified as type 1 (Th1) and type 2 (Th2) according to the cytokines they produce; interferon-gamma is produced by Th1, and interleukin-4 by Th2. We counted the circulating CD4-positive Th cells that produce interferon-gamma or interleukin-4 with an enzyme-linked immunospot assay.
Koju Kobayashi +11 more
semanticscholar +3 more sources
Helper T cells (Th) are classified as type 1 (Th1) and type 2 (Th2) according to the cytokines they produce; interferon-gamma is produced by Th1, and interleukin-4 by Th2. We counted the circulating CD4-positive Th cells that produce interferon-gamma or interleukin-4 with an enzyme-linked immunospot assay.
Koju Kobayashi +11 more
semanticscholar +3 more sources
Molecular Immunology, 1987
Mouse monoclonal antibodies (MAbs) have been prepared against rat T cell blasts. One MAb called MRC OX-40 recognized an antigen that differed from any previously described in that its expression was detected only on T blasts that also expressed the CD4 antigen.
D. Paterson +6 more
semanticscholar +3 more sources
Mouse monoclonal antibodies (MAbs) have been prepared against rat T cell blasts. One MAb called MRC OX-40 recognized an antigen that differed from any previously described in that its expression was detected only on T blasts that also expressed the CD4 antigen.
D. Paterson +6 more
semanticscholar +3 more sources

