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A Review of CD4 Positive T Lymphocytes Counts among HIV Positive Patients Attending a Nigerian Teaching Hospital

British Microbiology Research Journal, 2015
Aims and Objectives: To determine the baseline CD4 positive T lymphocytes count of HIV/AIDS treatment naive adults clients presenting for the first time treatment in Benue State University Teaching Hospital. Subjects and Methods: A total of 700 subjects age between 18 years to 70 years, were recruited for the study, comprising 600 HIV sero-positive ...
Nwadioha, S. I   +4 more
openaire   +2 more sources

HLA‐DQ allele‐restricted activation of nitroso sulfamethoxazole‐specific CD4‐positive T lymphocytes from patients with cystic fibrosis

Clinical & Experimental Allergy, 2015
SummaryBackgroundFor certain HLA allele‐associated drug hypersensitivity reactions, the parent drug has been shown to associate directly with the risk allele. In other forms of hypersensitivity, HLA risk alleles have not been identified and T cells are activated in an allele unrestricted manner.
M O, Ogese   +10 more
openaire   +2 more sources

Quantification of CD4-positive T lymphocytes

1995
Abstract Introduction The central lesion in HIV-induced immunodeficiency is the functional and numerical decrease in the CD4-positive population of T lymphocytes. Progressive loss of this key lymphoid population is associated with an increasing range and severity of cellular immunodeficiency and predisposition to ...
openaire   +1 more source

Circulatory CD4-Positive T-Lymphocyte Imbalance Mediated by Homocysteine-Induced AIM2 and NLRP1 Inflammasome Upregulation and Activation Is Associated with Human Abdominal Aortic Aneurysm

Journal of Vascular Research, 2020
<b><i>Introduction:</i></b> CD4-positive T lymphocytes (CD4 cells) play a significant role in human abdominal aortic aneurysm (AAA). However, we know little about the role of the different CD4 subtypes. <b><i>Objective:</i></b> We aimed to discover the circulatory CD4 phenotypic marker profile and the ...
Hao, Wang   +5 more
openaire   +2 more sources

Resistance of CD4-positive T lymphocytes to etoposide-induced apoptosis mediated by upregulation of Bcl-xL expression in patients with HTLV-I-associated myelopathy

Journal of Neuroimmunology, 2001
Human T-lymphotropic virus type I (HTLV-I)-associated myelopathy (HAM) is characterized by chronic inflammation of the spinal cord. The exact mechanisms that enhance the development of chronic myelopathy remain to be determined. One such mechanism could be an altered response of peripheral blood CD4(+) T lymphocytes to apoptotic stimuli.
S, Hamasaki   +8 more
openaire   +2 more sources

Human T lymphocytes expressing the C3b/C4b complement receptor type one (CR1, CD35) belong to Fcγ receptor-positive CD4-positive T cells

Cellular Immunology, 1989
The phenotypic characteristics of human T lymphocytes expressing the C3b/C4b complement receptor type one (CR1, CD35) were investigated using dual-color surface immunofluorescence and cytofluorometric analysis of stained peripheral blood mononuclear cells (PBMC) from normal individuals.
J H, Cohen   +4 more
openaire   +2 more sources

Modeling Changes in CD4-positive T-Lymphocyte Counts after the Start of Highly Active Antiretroviral Therapy and the Relation with Risk of Opportunistic Infections The Aquitaine Cohort, 1996–1997

American Journal of Epidemiology, 2001
Abstract After initiation of a treatment for human immunodeficiency virus type 1 infection containing a protease inhibitor, immune restoration associated with increases in CD4-positive (CD4+) T lymphocyte count may be delayed. In a sample of patients who had been prescribed protease inhibitors for the first time, the authors tested to ...
C, Binquet   +6 more
openaire   +2 more sources

[Clinicopathologic correlation between CD4-positive T lymphocyte counts and superficial lymphadenopathy in HIV-positive/AIDS patients].

Zhonghua bing li xue za zhi = Chinese journal of pathology, 2012
To explore the clinicopathological correlation between CD4(+) T lymphocyte count and superficial lymphadenopathy HIV/AIDS patients.A total of 1066 HIV/AIDS patients were included in this study. The incidence of superficial lymphadenopathy, peripheral blood CD4(+) T lymphocyte counts and histological features of superficial lymphadenopathy were analyzed.
Xiang-chan, Lu   +7 more
openaire   +1 more source

[Effect of CD4-positive T lymphocyte expression rate on pain control and prognosis in stage Ⅳ non-small cell lung cancer patients with cancerous pain].

Zhonghua yi xue za zhi, 2022
Objective: To investigate the effect of CD4-positive T lymphocyte expression rate on the pain control and prognosis of stage Ⅳ non-small cell lung cancer (NSCLC) patients with cancerous pain. Methods: The clinical data of 128 stage Ⅳ NSCLC patients with cancerous pain who were admitted to the Affiliated Cancer Hospital of Zhengzhou University from ...
H, Chen   +6 more
openaire   +1 more source

TNF-alpha mediated apoptosis of CD4 positive T-lymphocytes. A model of T-cell depletion in HIV infected individuals.

European journal of medical research, 1998
Apoptosis has been suggested to account for loss of CD4+ T-cells in HIV infected individuals. Aside from MHC II dependent superantigens no mediator for preferential apoptosis of CD4+ T-cell has been described. However, the expression of TNF-alpha is increased in HIV+ patients.
S A, Klein   +8 more
openaire   +1 more source

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