Results 241 to 250 of about 15,816,019 (291)

The Immunomodulatory Role of CD4-Positive Cytotoxic T-lymphocytes in Health and Disease

International Reviews of Immunology, 1999
Among the CD4-positive (CD4+) T-lymphocytes a population exists which expresses cytolytic activity. These 'killer' cells belong to the T helper type 1 (Th1) subset and if activated, express Fas-ligand (FasL) which induces apoptosis in Fas-positive target cells. The major targets of these CD4+ cytotoxic T-lymphocytes (CTL) are cells of the immune system,
Hahn S, Erb P
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Decrease of CD4-positive T Lymphocytes in Workers Exposed to Benzidine and Beta-naphthylamine

Archives of Environmental Health: An International Journal, 1993
T lymphocyte subpopulations (CD4+, CD8+, and CD3+ cells), Leu 11a-(CD16) positive lymphocytes, and total lymphocytes in peripheral blood in 52 male dyestuff workers were analyzed to determine the effects of benzidine and beta-naphthylamine on the human immune system.
S, Araki, T, Tanigawa, S, Ishizu, N, Minato   +3 more
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Mental stimulation increases circulating CD4-positive T lymphocytes: a preliminary study

Cognitive Brain Research, 2001
To stimulate the dorsolateral frontal cortex, 12 healthy, adult, human females played contract bridge for 1.5 h between initial and final blood sample collections. Flow cytometric analyses of samples, performed in triplicate, showed a significant increase in CD4-positive T lymphocytes.
M C, Diamond, J, Weidner, P, Schow, S, Grell, M, Everett   +4 more
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CD4-POSITIVE HELPER T LYMPHOCYTES MEDIATE MOUSE CARDIAC ALLOGRAFT REJECTION INDEPENDENT OF DONOR ALLOANTIGEN SPECIFIC CYTOTOXIC T LYMPHOCYTES

Transplantation, 1993
Mouse heterotopic cardiac allograft recipients were depleted of CD4+ or CD8+ T lymphocytes in vivo to assess cellular requirements for graft infiltration, tissue damage, and acute allograft rejection. Modified limiting dilution analysis was employed to quantitate IL-2-producing Th lymphocytes (HTL) and CTL infiltrating the graft.
D K, Bishop, S, Chan, W, Li, R D, Ensley, S, Xu, E J, Eichwald   +5 more
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Proteome database of unsensitized CD4 positive T lymphocytes in T cell receptor transgenic mice

ELECTROPHORESIS, 2003
AbstractWe established a two‐dimensional electrophoresis (2‐DE) mapping database of splenic CD4 T cells prepared from I‐Ad‐restricted ovalbumin (OVA)323‐339 specific T cell receptor (TCR) transgenic mice (OVA23‐3). First we examined the purification of CD4 T cells and found that the high purity of cells produced more accurate protein maps.
Tomohiro, Kaji, Satoshi, Hachimura, Shuichi, Kaminogawa   +2 more
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Removal of Autologous Activated CD4 Positive T Lymphocytes Also Result in Increased Colony-Forming Units (CFUs) in Patients With Myelodysplastic Syndromes.

Blood, 2009
Abstract Abstract 4862 Autologous activated CD4+ T lymphocytes (CD4+/CCR5+ double positive cells) in BMNC of 29 MDS patients were depleted or plused in in vitro cultures. That cultures with removed CD4+/CCR5+ cells exhibited significantly increased CFU generation.
Feng Xu
exaly   +2 more sources

CD4-positive T lymphocytes are required for the generation of the primary but not the secondary CD8-positive cytolytic T lymphocyte response to herpes simplex virus in C57BL/6 mice

Cellular Immunology, 1991
To understand the cellular basis for recovery from HSV infection, it is critical to identify functional interactions between HSV-specific T lymphocyte subpopulations involved in the generation of the optimal response. To this end, the requirement for CD4+ (L3T4+) T lymphocytes in the development of the primary and secondary CD8+ (Lyt-2+) cytolytic T ...
S R, Jennings, R H, Bonneau, P M, Smith, R M, Wolcott, R, Chervenak   +4 more
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Activated CD4-positive T-lymphocytes and impaired cell-mediated immunity in patients with carcinoma of the urinary bladder with schistosomiasis

Cancer, 1990
Patients with schistosomiasis of the urinary bladder (SB) associated with carcinoma of the bladder (SCB) or carcinoma of the prostate (SCP) have a variety of immunologic abnormalities, including the presence of HLA-DR+ and interleukin-2 receptor-positive (IL-2R+) T-lymphocytes in circulating blood.
S, Raziuddin, S, Shetty, A, Ibrahim, K, Patil   +3 more
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HELPER T LYMPHOCYTE UNRESPONSIVENESS TO CARDIAC ALLOGRAFTS FOLLOWING TRANSIENT DEPLETION OF CD4-POSITIVE CELLS

Transplantation, 1994
Initial treatment of heterotopic cardiac transplant recipients with anti-CD4 mAb promotes long-term (> 60 days) allograft survival. We have used modified limiting dilution analysis to quantitate donor alloantigen-reactive helper T lymphocytes (HTL) and CTL in mice bearing long-term cardiac allografts.
D K, Bishop, W, Li, S Y, Chan, R D, Ensley, J, Shelby, E J, Eichwald   +5 more
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