Results 21 to 30 of about 112,618 (124)

Erythrodermic CD4/CD8 Double-Negative Mycosis Fungoides: A Case Report

Case Reports in Oncology, 2021
Cutaneous T-cell lymphoma (CTCL) describes a group of lymphoproliferative disorders characterized by localization of neoplastic T lymphocytes to the skin. Mycosis fungoides (MF) represents the most common type of CTCL and accounts for ∼60% of all primary
Monira Abdullah Alnasser, Nour Marwan AlKhawajah, Nada Ghazi AlQadri, Asem Mustafa Shadid, Fahad M. Alsaif   +4 more
doaj   +1 more source

Prolonged enhancement of cytotoxic T lymphocytes in the post-recovery state of severe COVID-19

Journal of Intensive Care, 2021
We evaluated the peripheral blood immune responses of lymphocytes in severe Coronavirus disease 2019 (COVID-19) patients in different stages of recovery using single-cell mass cytometry.
Yumi Mitsuyama, Kazuma Yamakawa, Katsuhide Kayano, Miho Maruyama, Takeshi Wada, Satoshi Fujimi   +5 more
doaj   +1 more source

Glutamine or whey-protein supplementation on alloxan-induced diabetic rats. Effects on CD4+ and CD8+ lymphocytes Efeitos da oferta de glutamina ou de proteína do soro de leite sobre os linfócitos CD4+ e CD8+ em ratos diabéticos aloxano induzidos

Acta Cirúrgica Brasileira, 2007
PURPOSE: To evaluate the effects of glutamine (L-Gln) or whey-protein supplementation on CD4+ and CD8+ lymphocytes in alloxan-induced diabetic rats. METHODS: Thirty-two healthy male Wistar rats were used in the experiment.
Renato Motta Neto, Sergio Botelho Guimarães, Sônia Leite da Silva, José Napoleão da Cruz, Thiago Dias, Paulo Roberto Leitão de Vasconcelos   +5 more
doaj   +1 more source

Mice Deficient in Nucleoporin Nup210 Develop Peripheral T Cell Alterations

Frontiers in Immunology, 2018
The nucleopore is an essential structure of the eukaryotic cell, regulating passage between the nucleus and cytoplasm. While individual functions of core nucleopore proteins have been identified, the role of other components, such as Nup210, are poorly ...
Annemarie van Nieuwenhuijze, Annemarie van Nieuwenhuijze, Oliver Burton, Oliver Burton, Pierre Lemaitre, Pierre Lemaitre, Alice E. Denton, Ana Cascalho, Ana Cascalho, Rose E. Goodchild, Rose E. Goodchild, Bert Malengier-Devlies, Bert Malengier-Devlies, Bénédicte Cauwe, Bénédicte Cauwe, Michelle A. Linterman, Stephanie Humblet-Baron, Stephanie Humblet-Baron, Adrian Liston, Adrian Liston   +19 more
doaj   +1 more source

Clinical significance of assessing the subpopulation composition of blood lymphocytes in patients with infectious corneal lesions in high-risk keratoplasty

Российский офтальмологический журнал, 2020
The purpose is to study the shifts in the subpopulation composition of blood lymphocytes in patients with infectious corneal lesions, depending on the number of keratoplasties (KP) undergone by the patient.Material and methods.
V. V. Neroev, N. V. Balatskaya, E. V. Chentsova, I. G. Kulikova, H. M. Shamkhalova   +4 more
doaj   +1 more source

Characterization of CD4-Positive Lymphocytes in the Antiviral Response of Olive Flounder (Paralichthys oliveceus) to Nervous Necrosis Virus [PDF]

International Journal of Molecular Sciences, 2020
The presence of CD4 T lymphocytes has been described for several teleost species, while many of the main T cell subsets have not been characterized at a cellular level, because of a lack of suitable tools for their identification, e.g., monoclonal antibodies (mAbs) against cell markers.
Jin Hong Chun, Jassy Mary S. Lazarte, Si Won Kim, Jaesung Kim, Tae Sung Jung, Tae Sung Jung, Kim D. Thompson, Hyoung Jun Kim, Jae Wook Jung, Young Rim Kim, Jung Seok Lee, Ae Rin Lee   +11 more
openaire   +2 more sources

Activation of β1 integrins mediates proliferation and inhibits apoptosis of intestinal CD4-positive lymphocytes [PDF]

European Journal of Immunology, 2001
A characteristic of lamina propria lymphocytes (LPL) is their low proliferative response to stimuli of the CD3 pathway. beta(1) integrins were expressed on LPL; however, their function is unknown. Therefore, we determined whether beta(1) integrins contribute to T cell responses by providing costimulatory signals. Integrins on CD4(+) LPL of controls and
Stallmach, A, Giese, T, Pfister, K, Wittig, B M, Künne, S, Humphries, Martin J, Zeitz, M, Meuer, S C   +7 more
openaire   +4 more sources

Overexpression of PD-1 and CD39 in tumor-infiltrating lymphocytes compared with peripheral blood lymphocytes in triple-negative breast cancer.

PLoS ONE, 2022
Background and aimGrowing evidence highlighted the primary role of the immune system in the disease course of triple-negative breast cancer (TNBC). The study aim was to investigate the expression of PD-1 and CD39 on CD4+ and CD8+ cells infiltrating tumor
Asmaa M Zahran, Amal Rayan, Zeinab Albadry M Zahran, Wael M Y Mohamed, Dalia O Mohamed, Mona H Abdel-Rahim, Omnia El-Badawy   +6 more
doaj   +1 more source

Comparative evaluation of memory T cells in COVID-19 patients and the predictive role of CD4+CD8+ double positive T lymphocytes as a new marker.

Revista da Associação Médica Brasileira, 2020
BACKGROUND The COVID-19 pandemic has affected the entire world, posing a serious threat to human health. T cells play a critical role in the cellular immune response against viral infections. We aimed to reveal the relationship between T cell subsets and
Y. Kalpakçı, T. Hacıbekiroğlu, Gulay Trak, C. Karacaer, T. Demirci, H. Kocayiğit, C. Sunu, C. Varım, M. Falay   +8 more
semanticscholar   +1 more source

A ROLE FOR INTERLEUKIN 8 IN DIRECT REGULATION OF T CELL FUNCTIONAL ACTIVITY

Медицинская иммунология, 2017
CD3+T lymphocytes were isolated from normal donors by positive magnetic separation. Activation of the T cells with particles conjugated with antibodies to CD3, СD28 and СD2 molecules led to substantial increase in T cell production of interleukin-8 (IL-8)
M. E. Meniailo, V. V. Malashchenko, V. A. Shmarov, N. D. Gasatova, O. B. Melashchenko, A. G. Goncharov, G. V. Seledtsova, V. I. Seledtsov   +7 more
doaj   +1 more source