Results 291 to 300 of about 463,708 (346)

Autoimmune reactions to ACE2 triggered by SARS-CoV-2 S protein and their histopathological consequences. [PDF]

Sci Rep
Beduleva L, Fomina K, Khramova T, Terentiev A, Menshikova D, Terentieva O, Menshikov I, Sidorov A, Makhankova P, Abisheva N.   +9 more
europepmc   +1 more source

New approaches to treating chronic obstructive pulmonary disease with Colla corii asini

Animal Models and Experimental Medicine, EarlyView.
Colla corii asini improves chronic obstructive pulmonary disease (COPD) treatment through anti‐inflammatory, antioxidant, immune‐modulatory, and lung‐nourishing effects, addressing current therapeutic challenges via multitarget mechanisms. Abstract Chronic obstructive pulmonary disease (COPD) is one of the leading causes of death and disability ...
Wenchao Zhang, Siman Sun, Xiaoyu Fan, Jiuming He, Qing Li, Hongtao Jin   +5 more
wiley   +1 more source

Targeting Molecular Dysregulation in Ulcerative Colitis: A Paired Cellular Perspective on CD4⁺, CD8⁺, and IL-6 Immunohistochemistry. [PDF]

Int J Mol Sci
Mirica RE, Coman A, State M, Popp C.
europepmc   +1 more source

Pro‐Inflammatory c‐Met+ CD4 T Cells in Multiple Sclerosis

Annals of Neurology, EarlyView.
Objective Hepatocyte growth factor (HGF) binds exclusively the c‐Met surface receptor, and the HGF/c‐Met axis regulates T cell function in autoimmune diseases. We analyzed c‐Met expression on human CD4 T cells in the blood and cerebrospinal fluid (CSF) from patients with multiple sclerosis (MS) versus non‐inflammatory neurological disease (NIND), to ...
Gautier Breville, Mahdia Benkhoucha, Ayman Rezk, Ngoc Lan Tran, Isis Senoner, Amit Bar‐Or, Patrice H. Lalive   +6 more
wiley   +1 more source

A multi-dimensional risk signature for lupus nephritis in systemic lupus erythematosus: integrating symptoms, biochemistry and immune cell profiles. [PDF]

Front Immunol
Liu X, Xiao Z, Zhang X, Li J, Yuan Y, Li N, Zhang X, Li S, Gao L.   +8 more
europepmc   +1 more source

Confined B‐Cell Reconstruction and High T‐Cell Clonality Define Clinical Response to Cladribine Treatment

Annals of Neurology, EarlyView.
Cladribine tablets are approved for relapsing multiple sclerosis, mediating their clinical effect by moderately depleting lymphocytes. In a prospective, monocentric study including 22 patients completing 2 annual cycles of cladribine, B‐ and T‐cell receptor repertoires and relapse activity were assessed at baseline and after 24 months. T‐cell clonality
Tilman Schneider‐Hohendorf, Maria Eveslage, Timo Wirth, Christian Wünsch, Eva M. Schumann, Jan D. Lünemann, Heinz Wiendl, Luisa Klotz, Nicholas Schwab   +8 more
wiley   +1 more source

Evaluating Pediatric Reference Ranges for Extended Immunophenotyping from a Finnish Cohort against Published References. [PDF]

J Clin Immunol
Äärimaa E, Kesäläinen A, Askeli S, Toivonen A, Savonius O, Brück O, Lusila P, Vettenranta K, Heinonen S, Jahnukainen T, Koskenvuo M, Siitonen S, Lehtimäki S, Kekäläinen E.   +13 more
europepmc   +1 more source

Engineering Tertiary Lymphoid Structures: Nanomedicine, Bioengineering, and Biomaterials for Precision Immunotherapy

Advanced NanoBiomed Research, EarlyView.
This review explains how biomaterials and nanoparticles can be used to induce or modulate tertiary lymphoid structures (TLSs), which are ectopic immune hubs that form in nonlymphoid tissues during chronic disease and cancer. By comparing different methods, the article highlights design principles for modeling TLSs or recapitulating specific TLS ...
Shaza Karaman, Mei ElGindi, Jeremy Teo
wiley   +1 more source

Histopathological Evaluation of the Pericardium in CABG Patients With and Without Prior SARS-CoV-2 Infection: A Prospective Observational Study. [PDF]

Med Sci Monit
Ereren E, Ağırbaş H, Karal İH, Koç Şahin S, Tatlıdil F.   +4 more
europepmc   +1 more source

IL-7: a potential next-generation adjuvant for immune cell therapies. [PDF]

Front Immunol
Hotchkiss RS, DiPersio JF, Yee C, Pachynski RK, Van Den Brink MRM.   +4 more
europepmc   +1 more source