Results 311 to 320 of about 463,708 (346)
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Decrease of CD4-positive T lymphocytes in workers exposed to benzidine and beta-naphthylamine.
Archives of Environmental Health: An International Journal, 1993T lymphocyte subpopulations (CD4+, CD8+, and CD3+ cells), Leu 11a-(CD16) positive lymphocytes, and total lymphocytes in peripheral blood in 52 male dyestuff workers were analyzed to determine the effects of benzidine and beta-naphthylamine on the human immune system.
S. Araki +3 more
semanticscholar +3 more sources
Depletion of CD4-positive T-lymphocytes enhances post-stroke endogenous neurogenesis
Neuroscience Research, 2010Orie Saino +7 more
semanticscholar +2 more sources
Cellular Immunology, 1991
To understand the cellular basis for recovery from HSV infection, it is critical to identify functional interactions between HSV-specific T lymphocyte subpopulations involved in the generation of the optimal response. To this end, the requirement for CD4+ (L3T4+) T lymphocytes in the development of the primary and secondary CD8+ (Lyt-2+) cytolytic T ...
S. Jennings +4 more
semanticscholar +3 more sources
To understand the cellular basis for recovery from HSV infection, it is critical to identify functional interactions between HSV-specific T lymphocyte subpopulations involved in the generation of the optimal response. To this end, the requirement for CD4+ (L3T4+) T lymphocytes in the development of the primary and secondary CD8+ (Lyt-2+) cytolytic T ...
S. Jennings +4 more
semanticscholar +3 more sources
Journal of Medical Virology, 2003
AbstractIt was proposed recently that CEM CD4‐positive T cells infected chronically by herpes simplex virus type 1 (HSV‐1) and human immunodeficiency virus type 1 (HIV‐1) (CEMHSV/HIV) may be used as a model for studying HIV/HSV interactions. To ascertain whether HSV‐HIV coinfection of T lymphocytes has a role in promoting progression of lentiviral ...
A. Calistri, C. Parolin, G. Palù
semanticscholar +3 more sources
AbstractIt was proposed recently that CEM CD4‐positive T cells infected chronically by herpes simplex virus type 1 (HSV‐1) and human immunodeficiency virus type 1 (HIV‐1) (CEMHSV/HIV) may be used as a model for studying HIV/HSV interactions. To ascertain whether HSV‐HIV coinfection of T lymphocytes has a role in promoting progression of lentiviral ...
A. Calistri, C. Parolin, G. Palù
semanticscholar +3 more sources
Journal of Gastroenterology, 1998
Helper T cells (Th) are classified as type 1 (Th1) and type 2 (Th2) according to the cytokines they produce; interferon-gamma is produced by Th1, and interleukin-4 by Th2. We counted the circulating CD4-positive Th cells that produce interferon-gamma or interleukin-4 with an enzyme-linked immunospot assay.
Koju Kobayashi +11 more
semanticscholar +3 more sources
Helper T cells (Th) are classified as type 1 (Th1) and type 2 (Th2) according to the cytokines they produce; interferon-gamma is produced by Th1, and interleukin-4 by Th2. We counted the circulating CD4-positive Th cells that produce interferon-gamma or interleukin-4 with an enzyme-linked immunospot assay.
Koju Kobayashi +11 more
semanticscholar +3 more sources
The immunomodulatory role of CD4-positive cytotoxic T-lymphocytes in health and disease.
International Reviews of Immunology, 1999Among the CD4-positive (CD4+) T-lymphocytes a population exists which expresses cytolytic activity. These 'killer' cells belong to the T helper type 1 (Th1) subset and if activated, express Fas-ligand (FasL) which induces apoptosis in Fas-positive target cells. The major targets of these CD4+ cytotoxic T-lymphocytes (CTL) are cells of the immune system,
S. Hahn, P. Erb
semanticscholar +3 more sources
Molecular Immunology, 1987
Mouse monoclonal antibodies (MAbs) have been prepared against rat T cell blasts. One MAb called MRC OX-40 recognized an antigen that differed from any previously described in that its expression was detected only on T blasts that also expressed the CD4 antigen.
D. Paterson +6 more
semanticscholar +3 more sources
Mouse monoclonal antibodies (MAbs) have been prepared against rat T cell blasts. One MAb called MRC OX-40 recognized an antigen that differed from any previously described in that its expression was detected only on T blasts that also expressed the CD4 antigen.
D. Paterson +6 more
semanticscholar +3 more sources
The Journal of Pathology, 2014
AbstractTat, the transactivation factor of human immunodeficiency virus type 1 (HIV‐1), represents one of the major players mediating the loss of CD4‐positive T‐lymphocytes in HIV‐1‐infected patients, primarily due to the ability of Tat to trigger apoptosis. However, the molecular events underlying this process remain elusive. In this study, we provide
Min Liu +7 more
semanticscholar +3 more sources
AbstractTat, the transactivation factor of human immunodeficiency virus type 1 (HIV‐1), represents one of the major players mediating the loss of CD4‐positive T‐lymphocytes in HIV‐1‐infected patients, primarily due to the ability of Tat to trigger apoptosis. However, the molecular events underlying this process remain elusive. In this study, we provide
Min Liu +7 more
semanticscholar +3 more sources
Proteome database of unsensitized CD4 positive T lymphocytes in T cell receptor transgenic mice
ELECTROPHORESIS, 2003AbstractWe established a two‐dimensional electrophoresis (2‐DE) mapping database of splenic CD4 T cells prepared from I‐Ad‐restricted ovalbumin (OVA)323‐339 specific T cell receptor (TCR) transgenic mice (OVA23‐3). First we examined the purification of CD4 T cells and found that the high purity of cells produced more accurate protein maps.
Tomohiro, Kaji +2 more
openaire +2 more sources
Transplantation, 1994
Initial treatment of heterotopic cardiac transplant recipients with anti-CD4 mAb promotes long-term (> 60 days) allograft survival. We have used modified limiting dilution analysis to quantitate donor alloantigen-reactive helper T lymphocytes (HTL) and CTL in mice bearing long-term cardiac allografts.
D K, Bishop +5 more
openaire +2 more sources
Initial treatment of heterotopic cardiac transplant recipients with anti-CD4 mAb promotes long-term (> 60 days) allograft survival. We have used modified limiting dilution analysis to quantitate donor alloantigen-reactive helper T lymphocytes (HTL) and CTL in mice bearing long-term cardiac allografts.
D K, Bishop +5 more
openaire +2 more sources