CD3+CD4+LAP+Foxp3-regulatory cells of the colonic lamina propria limit disease extension in ulcerative colitis [PDF]
, 2018 Background and Aims: In ulcerative colitis (UC), inflammation begins in the rectum and can extend proximally throughout the entire colon. The extension of inflammation is an important determinant of disease course, and may be limited by the action of ...
Amendola, Antonello +10 more
core +3 more sources
altered expression of cD300a inhibitory receptor on cD4+ T cells From human immunodeficiency Virus-1-infected Patients: association With Disease Progression Markers. [PDF]
, 2018 The ability of the CD300a inhibitory receptor to modulate immune cell functions and its involvement in the pathogenesis of many diseases has aroused a great interest in this molecule.
Genebat González, Miguel +3 more
core +1 more source
Mucocutaneous Manifestations in HIV/AIDS Patients
Berkala Ilmu Kesehatan Kulit dan Kelamin (Periodical of Dermatology and Venerology), 2021 Background: The main target of human immunodeficiency virus (HIV) is cluster of differentiation 4 (CD4) T lymphocytes and several other immune cells that have CD4 receptors.
Afif Nurul Hidayati +10 more
doaj +1 more source
Association between disruption of CD4 receptor dimerization and increased human immunodeficiency virus type 1 entry [PDF]
, 2006 Affiliation: Département de microbiologie et immunologie, Faculté de médecine, Université de Montréal & Institut de Recherches Cliniques de MontréalBACKGROUND:Human immunodeficiency virus (HIV) enters target cells by a membrane fusion process that ...
Bourgeois, Rachel +3 more
core +3 more sources
Immunosuppressive Acidic Protein- Haematological correlates in HIV infected subjects
Asian Journal of Medical Sciences, 2017 Background: Immunosuppressive Acidic protein (IAP) is a marker of the extent of immune defects occurring in most cancers. Its correlation with CD4 cell count used as an indicator of immune function and disease progression in Human Immuno-deficiency Virus
Olayanju Ayodeji Olusola
doaj +1 more source
Combinatorial functions of two chimeric antibodies directed to human CD4 and one directed to the a-chain of the human interleukin-2 receptor [PDF]
, 1992 The general feasibility of chimerization of monoclonal antibodies (mAbs) has already been shown for a large number of them. In order to evaluate in vitro parameters relevant to immunosuppressive therapy, we have chimerized and synthesized two anti-CD4 ...
Flieger, Dimitri +10 more
core +1 more source
Indian Journal of Vascular and Endovascular Surgery, 2020 Aim: To assess the prevalence of peripheral arterial occlusive disease (PAOD) in human immunodeficiency virus (HIV)-infected Omani patients and to assess the potential risk factors in this group.
Ahmed Al-Aufi +5 more
doaj +1 more source
OncoImmunology, 2021 OX40 (CD134) is a co-stimulatory molecule mostly expressed on activated T lymphocytes. Previous reports have shown that OX40 can be an immuno-oncology target and a clinical biomarker for cancers of various organs.
Hiroshi Yokouchi +23 more
doaj +1 more source
CD4 Phosphorylation Partially Reverses Nef Down-Regulation of CD4 [PDF]
The Journal of Immunology, 2004 Abstract HIV Nef down-regulates CD4 from the cell surface in the absence of CD4 phosphorylation, whereas PMA down-regulates CD4 through a phosphorylation-dependent pathway. In this study we show that the down-regulation of CD4 in human Jurkat T cells expressing Nef was nearly complete (∼95%), whereas that induced by PMA was partial (∼40%)
Yong-Jiu, Jin +3 more
openaire +2 more sources
Effector memory differentiation increases detection of replication-competent HIV-l in resting CD4+ T cells from virally suppressed individuals. [PDF]
, 2019 Studies have demonstrated that intensive ART alone is not capable of eradicating HIV-1, as the virus rebounds within a few weeks upon treatment interruption.
Bale, Michael J +13 more
core +1 more source