Results 11 to 20 of about 139,619 (346)
Cell Adhesion & Migration, 2021 We developed a computer-assisted platform using laser scanning confocal microscopy to 3D reconstruct in real-time interactions between metastatic breast cancer cells and human umbilical vein endothelial cells (HUVECs).
Deborah J. Wessels +13 more
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The effect of hyaluronic acid on nucleus pulposus extracellular matrix production through hypoxia-inducible factor-1α transcriptional activation of CD44 under hypoxia [PDF]
European Cells & Materials, 2021 Intervertebral disc degeneration (IDD) is the leading cause of low-back pain. Implantation of hyaluronic acid (HA) is potentially a therapeutic strategy for IDD, but its pharmacological effects and mechanism under hypoxic conditions remain unclear.
F Zhang +7 more
doaj +1 more source
Journal of Radiation and Cancer Research, 2020 Background: Periampullary cancer (PC) is a global medical burden. Less than 5% of patients experience an overall survival of 5 years or more. The study aims to analyze the importance of epidermal growth factor receptor (EGFR)/insulin-like growth factor 1
Biswabandhu Bankura +4 more
doaj +1 more source
Сибирский онкологический журнал, 2021 Background. Gastric cancer is the second leading cause of cancer-related death due to advanced disease. A special role in the pathogenesis and metastasis of the tumor is assigned to tumor stem cells (TSC ), responsible for resistance to chemotherapy and
A. B. Sagakyants +10 more
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CD44 (CD44 molecule (Indian blood group)) [PDF]
Atlas of Genetics and Cytogenetics in Oncology and Haematology, 2011 Review on CD44 (CD44 molecule (Indian blood group)), with data on DNA, on the protein encoded, and where the gene is implicated.
Sen, YP, Yip, GW
openaire +3 more sources
Rambam Maimonides Medical Journal, 2021 Objectives: To study the correlation between the putative cancer stem cell (CSC) markers aldehyde dehydrogenase 1 (ALDH1), cluster of differentiation 44 (CD44), sex-determining region Y-box 2 (SOX2), and octamer-binding protein 4 (OCT4) and human ...
Prasanth Thankappan +5 more
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CD44 as a tumor biomarker and therapeutic target
Experimental Hematology & Oncology, 2020 CD44, a complex transmembrane glycoprotein, exists in multiple molecular forms, including the standard isoform CD44s and CD44 variant isoforms. CD44 participates in multiple physiological processes, and aberrant expression and dysregulation of CD44 ...
Hanxiao Xu +4 more
semanticscholar +1 more source
Cancer Cell CD44 Mediates Macrophage/Monocyte-Driven Regulation of Head and Neck Cancer Stem Cells
Cancer Research, 2020 These findings establish a mechanistic link between tumor cell CD44, TAM, and CSC properties at the tumor-stroma interface that can serve as a vital area of focus for target and drug discovery.
Karina E Gomez +15 more
semanticscholar +1 more source
Beilstein Journal of Nanotechnology, 2021 Nanomedicine has emerged as a novel cancer treatment and diagnostic modality, whose design constantly evolves towards increasing the safety and efficacy of the chemotherapeutic and diagnostic protocols.
Nikola Geskovski +5 more
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The biology and role of CD44 in cancer progression: therapeutic implications
Journal of Hematology & Oncology, 2018 CD44, a non-kinase transmembrane glycoprotein, is overexpressed in several cell types including cancer stem cells and frequently shows alternative spliced variants that are thought to play a role in cancer development and progression.
Chen Chen +3 more
semanticscholar +1 more source