Results 11 to 20 of about 229,337 (378)
Understanding Hyaluronan Receptor (CD44) Interaction, HA-CD44 Activated Potential Targets in Cancer Therapeutics [PDF]
Advanced Pharmaceutical Bulletin, 2021 Cancer is a complex mechanism involving a series of cellular events. The glycoproteins such as hyaluronan (HA) are a significant element of extracellular matrix (ECM), involve in the onset of cancer developmental process.
Gul-e-Saba Chaudhry +5 more
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High Expression of CD44 Predicts a Poor Prognosis in Glioblastomas
Cancer Management and Research, 2020 Daolin Si,1 Fei Yin,1 Jing Peng,1 Guangying Zhang2 1Department of Pediatric Neurology, Xiangya Hospital, Central South University, Changsha, Hunan Province 410008, People’s Republic of China; 2Department of Oncology, Xiangya Hospital, Central South
Si D, Yin F, Peng J, Zhang G
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Comparative characteristic of lung cancer stem-like cells generated in vitro under different culture conditions [PDF]
The Ukrainian Biochemical Journal, 2021 Cancer stem cells (CSCs) play an important role in resistance to cancer treatment and recurrence developing. The aim of this study was to obtain cell culture of MOR line non-small cell lung cancer cells enriched in CSCs and to investigate its functional ...
O. V. Skachkova +4 more
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CD44: A Multifunctional Mediator of Cancer Progression
Biomolecules, 2021 CD44, a non-kinase cell surface transmembrane glycoprotein, has been widely implicated as a cancer stem cell (CSC) marker in several cancers. Cells overexpressing CD44 possess several CSC traits, such as self-renewal and epithelial-mesenchymal transition
Malak Hassn Mesrati +3 more
semanticscholar +1 more source
Сибирский онкологический журнал, 2021 Background. Gastric cancer is the second leading cause of cancer-related death due to advanced disease. A special role in the pathogenesis and metastasis of the tumor is assigned to tumor stem cells (TSC ), responsible for resistance to chemotherapy and
A. B. Sagakyants +10 more
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CD44-Targeted Nanocarrier for Cancer Therapy
Frontiers in Pharmacology, 2022 Cluster of differentiation 44 (CD44) is a cell surface glycoprotein overexpressed in varieties of solid tumors including pancreatic, breast, ovary, brain, and lung cancers.
Prashant Kesharwani +4 more
semanticscholar +1 more source
CD44 related stemness maneuvers oral squamous cell carcinoma biology
Indian Journal of Pathology and Microbiology, 2022 Introduction: Despite the commendable advancements in oral squamous cell carcinoma (OSCC) diagnostics and therapeutics, it remains a considerable medical challenge. Recent evidence suggests that small populations of stem-like cancer cells are responsible
Ankita Tandon +2 more
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The state of CD44 activation in cancer progression and therapeutic targeting
The FEBS Journal, 2021 CD44, a non‐kinase transmembrane glycoprotein, is ubiquitously expressed on various types of cells, especially cancer stem cells (CSCs), and has been implicated in cancer onset and aggressiveness.
Qian Guo, Cuixia Yang, F. Gao
semanticscholar +1 more source