Results 21 to 30 of about 118,496 (262)

CD44 Expression in Papillary Thyroid Carcinoma and its Correlation with Prognostic Factors [PDF]

Journal of Mazandaran University of Medical Sciences, 2023
Background and purpose: Identifying the prognostic factors of malignancies is of particular importance in therapeutic decisions and identification of high-risk patients.
Fatemeh Baghertash, Mohammadreza Jalali Nadoushan   +1 more
doaj  

89Zr-Labeled Multifunctional Liposomes Conjugate Chitosan for PET-Trackable Triple-Negative Breast Cancer Stem Cell Targeted Therapy

International Journal of Nanomedicine, 2020
Rui Yang,1,* Mudan Lu,2,* Lan Ming,1,* Yu Chen,1 Kai Cheng,1 Jie Zhou,1 Shiwen Jiang,1 Zhenyu Lin,3 Daozhen Chen1 1Research Institute for Reproductive Health and Genetic Diseases, Affiliated Wuxi Maternity and Child Health Care Hospital of Nanjing ...
Yang R, Lu M, Ming L, Chen Y, Cheng K, Zhou J, Jiang S, Lin Z, Chen D   +8 more
doaj  

Human breast milk stem cells: a new challenge for perinatologists

Journal of Pediatric and Neonatal Individualized Medicine, 2016
The lactating mammary gland contains a stem cells population with multilineage potentialities. Recently it was also shown that breast milk contains a heterogeneous population of stem cells that have the potential to differentiate in vitro, under the ...
Giuseppina Pichiri, Daniele Lanzano, Monica Piras, Angelica Dessì, Alessandra Reali, Melania Puddu, Antonio Noto, Vassilios Fanos, Carlo Coni, Gavino Faa, Pierpaolo Coni   +10 more
doaj   +1 more source

Granulocyte colony-stimulating factor induces the migration of non-resident cells to intracerebral hemorrhage

Zaporožskij Medicinskij Žurnal, 2023
The aim of the study is to determine the effect of granulocyte colony-stimulating factor (rHuG-CSF) on the migration of non-resident cells into the region of intracerebral hemorrhage (ICH), which can potentially be considered as mesenchymal stem cells.
A. V. Kuraieva, S. I. Savosko, O. M. Grabovoy, O. M. Makarenko   +3 more
doaj   +1 more source

CD44 (CD44 molecule (Indian blood group)) [PDF]

Atlas of Genetics and Cytogenetics in Oncology and Haematology, 2011
Review on CD44 (CD44 molecule (Indian blood group)), with data on DNA, on the protein encoded, and where the gene is implicated.
Sen, YP, Yip, GW
openaire   +2 more sources

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

Molecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang, Ayesha Alvero, Yi Qin, Mingjin Wang, Alexandra Fox, Yanfeng Li, Michael Millman, Amy Kemper, Gil Mor, Xian Shuang Liu, Michael Chopp, Zheng Gang Zhang, Yi Zhang   +12 more
wiley   +1 more source

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

Molecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu, Nicolas J. Niklaus, Anna M. Schläfli, Igor Tokarchuk, Magali Humbert, Federico La Manna, Bich Vu, David Maul, Ramin Radpour, Marianna Kruithof‐de Julio, Inti Zlobec, Jörn Dengjel, Bruce E. Torbett, Mario P. Tschan   +13 more
wiley   +1 more source

PAK1 activation drives divergent resistance mechanisms to aromatase inhibition and tamoxifen in a luminal: A breast cancer model

Molecular Oncology, EarlyView.
Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller, Janina Müller, Efstathios‐Iason Vlachavas, Lukas Beumers, Lena Fleischhacker, Sara Burmester, Angelika Wörner, Sabine Karolus, Dominic Helm, Cindy Körner, Stefan Wiemann   +10 more
wiley   +1 more source

High Expression of CD44 Predicts a Poor Prognosis in Glioblastomas

Cancer Management and Research, 2020
Daolin Si,1 Fei Yin,1 Jing Peng,1 Guangying Zhang2 1Department of Pediatric Neurology, Xiangya Hospital, Central South University, Changsha, Hunan Province 410008, People’s Republic of China; 2Department of Oncology, Xiangya Hospital, Central South
Si D, Yin F, Peng J, Zhang G
doaj  

Derivation and characterization of retinal pigment epithelium from urine‐derived iPSCs

FEBS Open Bio, EarlyView.
Age‐related macular degeneration causes vision loss via RPE dysfunction and loss. Traditional iPSC therapies rely on invasive biopsies, limiting scalability. Here, we utilize urine‐derived stem cells as an accessible source to generate u‐iPSCs, successfully differentiated into pigmented RPE. This “Urine‐to‐Retina” platform provides a promising path for
Daniella Beiner, Hainan Zhu, Carol Christine Bosholm, Heuy‐Ching Wang, Tracy Criswell, Anthony Atala, Jian‐Xing Ma, Yuanyuan Zhang   +7 more
wiley   +1 more source