Results 11 to 20 of about 118,496 (262)
Objectives: To study the correlation between the putative cancer stem cell (CSC) markers aldehyde dehydrogenase 1 (ALDH1), cluster of differentiation 44 (CD44), sex-determining region Y-box 2 (SOX2), and octamer-binding protein 4 (OCT4) and human ...
Prasanth Thankappan +5 more
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Abstract Objective. —To test the hypothesis that CD44 standard (CD44[s]) and its other variants, CD44v6 and CD44v7-8, might be useful markers of squamous differentiation in epithelial tumors. Design.
Clare M. Isacke, Michael A. Horton
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ITGB1BP1, a Novel Transcriptional Target of CD44-Downstream Signaling Promoting Cancer Cell Invasion
Salma M S Ahmad, Hanan Nazar, Md Mizanur Rahman, Radoslaw Stefan Rusyniak, Allal Ouhtit Biological Sciences Program, Department of Biological and Environmental Sciences, College of Arts and Science, Qatar University, Doha, QatarCorrespondence: Allal ...
Ahmad SMS +4 more
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Nanomedicine has emerged as a novel cancer treatment and diagnostic modality, whose design constantly evolves towards increasing the safety and efficacy of the chemotherapeutic and diagnostic protocols.
Nikola Geskovski +5 more
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A perspective on challenges and opportunities in characterizing oral cancer stem cells
Cancer stem cells (CSCs) or tumor-initiating cells (TICs) represent a minority population of cells in a tumor that can self-renew and re-create the heterogeneity of the entire tumor. Cell lines, patient-derived tumor cells, and patient-derived xenografts
Subhashini Sadasivam +1 more
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Glioma, one of the most common brain tumors, remains a challenge worldwide. Due to the specific biological barriers such as blood–brain barrier (BBB), cancer stem cells (CSCs), tumor associated macrophages (TAMs), and vasculogenic mimicry channels (VMs),
Liuqing Yang +8 more
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Epithelial ovarian cancer is a deadly cancer, cancer recurrence and resistance post surgical staging and chemotherapy are major problems which will eventually occur in most advanced stage ovarian cancer.
PUNGKY MULAWARDHANA +2 more
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Hyaluronic acid-coated niosomal sorafenib targets CD44 and suppresses NF‑κB signalling in oral squamous cell carcinoma [PDF]
Objective(s): Oral squamous cell carcinoma (OSCC) remains highly lethal and is driven, in part, by chronic NF-κB-mediated inflammation. Sorafenib, a multikinase inhibitor of RAF/VEGFR/PDGFR, can suppress these pathways, but its clinical utility is ...
Ting Wu +3 more
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Stem cell-like circulating tumor cells indicate poor prognosis in gastric cancer
Introduction Circulating tumor cells (CTCs) have the characteristics of cancer stem cells and play an important role in the recurrence and metastasis of tumors.
Wang Yi-Wen +4 more
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Cheng Xing, Yatong Li, Cheng Ding, Shunda Wang, Hanyu Zhang, Lixin Chen, Pengyu Li, Menghua Dai Department of General Surgery, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, 100730,
Xing C +7 more
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