Results 11 to 20 of about 145,654 (260)
Comparative characteristic of lung cancer stem-like cells generated in vitro under different culture conditions [PDF]
Cancer stem cells (CSCs) play an important role in resistance to cancer treatment and recurrence developing. The aim of this study was to obtain cell culture of MOR line non-small cell lung cancer cells enriched in CSCs and to investigate its functional ...
O. V. Skachkova +4 more
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Background. Gastric cancer is the second leading cause of cancer-related death due to advanced disease. A special role in the pathogenesis and metastasis of the tumor is assigned to tumor stem cells (TSC ), responsible for resistance to chemotherapy and
A. B. Sagakyants +10 more
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CD44 related stemness maneuvers oral squamous cell carcinoma biology
Introduction: Despite the commendable advancements in oral squamous cell carcinoma (OSCC) diagnostics and therapeutics, it remains a considerable medical challenge. Recent evidence suggests that small populations of stem-like cancer cells are responsible
Ankita Tandon +2 more
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Characterisation of apoptotic responses in human keratinocytes expressnig alpha-6 integrin and CD44 [PDF]
PhDa6 integrin has previously been proposed as a human keratinocyte stem cell markers. CD44-positive cells in epithelial tumours have been identified as potential cancer stem cells (CSCs) and display increased survival following chemotherapy ...
Wray, Helen
core +4 more sources
Background: Periampullary cancer (PC) is a global medical burden. Less than 5% of patients experience an overall survival of 5 years or more. The study aims to analyze the importance of epidermal growth factor receptor (EGFR)/insulin-like growth factor 1
Biswabandhu Bankura +4 more
doaj +1 more source
We developed a computer-assisted platform using laser scanning confocal microscopy to 3D reconstruct in real-time interactions between metastatic breast cancer cells and human umbilical vein endothelial cells (HUVECs).
Deborah J. Wessels +13 more
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The aim of the study is to determine the effect of granulocyte colony-stimulating factor (rHuG-CSF) on the migration of non-resident cells into the region of intracerebral hemorrhage (ICH), which can potentially be considered as mesenchymal stem cells.
A. V. Kuraieva +3 more
doaj +1 more source
Expression and modulation of CD44 variant isoforms in humans [PDF]
CD44 is a ubiquitous surface molecule that exists as a number of isoforms, generated by alternative splicing of 10 "variant" exons. Little is known about the expression and function of the variant isoforms, except that certain isoforms may play a role in
Mackay, C. R. +11 more
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Regulation of Fas mediated apoptosis by CD44 [PDF]
Over the last decade, apoptosis has grown from an obscure process to a complex and interesting scientific field, and many players have been identified.
Mielgo Iza, Ainhoa
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Analysis of CD44-containing lipid rafts: Recruitment of annexin II and stabilization by the actin cytoskeleton [PDF]
CD44, the major cell surface receptor for hyaluronic acid (HA), was shown to localize to detergent-resistant cholesterol-rich microdomains, called lipid rafts, in fibroblasts and blood cells.
Ursula Günthert +17 more
core +1 more source

