Results 11 to 20 of about 145,654 (260)

Comparative characteristic of lung cancer stem-like cells generated in vitro under different culture conditions [PDF]

open access: yesThe Ukrainian Biochemical Journal, 2021
Cancer stem cells (CSCs) play an important role in resistance to cancer treatment and recurrence developing. The aim of this study was to obtain cell culture of MOR line non-small cell lung cancer cells enriched in CSCs and to investigate its functional ...
O. V. Skachkova   +4 more
doaj   +1 more source

FEATURES OF EXPRESSION OF CD133 AND CD44 MARKERS OF TUMOR STEM CELLS WITH METASTATIC AND NON-METASTATIC GASTRIC CANCER

open access: yesСибирский онкологический журнал, 2021
Background. Gastric cancer is the second leading cause of cancer-related death due to advanced disease. A special role in the pathogenesis and metastasis of the tumor is assigned to tumor stem cells (TSC ),  responsible for resistance to chemotherapy and
A. B. Sagakyants   +10 more
doaj   +1 more source

CD44 related stemness maneuvers oral squamous cell carcinoma biology

open access: yesIndian Journal of Pathology and Microbiology, 2022
Introduction: Despite the commendable advancements in oral squamous cell carcinoma (OSCC) diagnostics and therapeutics, it remains a considerable medical challenge. Recent evidence suggests that small populations of stem-like cancer cells are responsible
Ankita Tandon   +2 more
doaj   +1 more source

Characterisation of apoptotic responses in human keratinocytes expressnig alpha-6 integrin and CD44 [PDF]

open access: yes, 2010
PhDa6 integrin has previously been proposed as a human keratinocyte stem cell markers. CD44-positive cells in epithelial tumours have been identified as potential cancer stem cells (CSCs) and display increased survival following chemotherapy ...
Wray, Helen
core   +4 more sources

Activation of epidermal growth factor receptor/insulin-like growth factor 1 receptor-β-Catenin-CD44 pathway in periampullary cancer

open access: yesJournal of Radiation and Cancer Research, 2020
Background: Periampullary cancer (PC) is a global medical burden. Less than 5% of patients experience an overall survival of 5 years or more. The study aims to analyze the importance of epidermal growth factor receptor (EGFR)/insulin-like growth factor 1
Biswabandhu Bankura   +4 more
doaj   +1 more source

Directed movement toward, translocation along, penetration into and exit from vascular networks by breast cancer cells in 3D

open access: yesCell Adhesion & Migration, 2021
We developed a computer-assisted platform using laser scanning confocal microscopy to 3D reconstruct in real-time interactions between metastatic breast cancer cells and human umbilical vein endothelial cells (HUVECs).
Deborah J. Wessels   +13 more
doaj   +1 more source

Granulocyte colony-stimulating factor induces the migration of non-resident cells to intracerebral hemorrhage

open access: yesZaporožskij Medicinskij Žurnal, 2023
The aim of the study is to determine the effect of granulocyte colony-stimulating factor (rHuG-CSF) on the migration of non-resident cells into the region of intracerebral hemorrhage (ICH), which can potentially be considered as mesenchymal stem cells.
A. V. Kuraieva   +3 more
doaj   +1 more source

Expression and modulation of CD44 variant isoforms in humans [PDF]

open access: yes, 1994
CD44 is a ubiquitous surface molecule that exists as a number of isoforms, generated by alternative splicing of 10 "variant" exons. Little is known about the expression and function of the variant isoforms, except that certain isoforms may play a role in
Mackay, C. R.   +11 more
core   +1 more source

Regulation of Fas mediated apoptosis by CD44 [PDF]

open access: yes, 2005
Over the last decade, apoptosis has grown from an obscure process to a complex and interesting scientific field, and many players have been identified.
Mielgo Iza, Ainhoa
core   +1 more source

Analysis of CD44-containing lipid rafts: Recruitment of annexin II and stabilization by the actin cytoskeleton [PDF]

open access: yes, 1999
CD44, the major cell surface receptor for hyaluronic acid (HA), was shown to localize to detergent-resistant cholesterol-rich microdomains, called lipid rafts, in fibroblasts and blood cells.
Ursula Günthert   +17 more
core   +1 more source

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