Results 31 to 40 of about 145,654 (260)
Molecules, 2020 Novel reduction-responsive hyaluronic acid−chitosan−lipoic acid nanoparticles (HACSLA-NPs) were designed and synthesized for effective treatment of breast cancer by targeting Cluster of Differentiation 44 (CD44)-overexpressing cells and ...
Somayeh Rezaei +4 more
doaj +1 more source
Indian Journal of Pathology and Microbiology, 2023 Introduction: Minimal change nephrotic syndrome (MCNS) and focal segmental glomerulosclerosis (FSGS) are the two common causes of nephrotic syndrome (NS) in both children and adults with overlapping clinical features, but with distinct prognostic and ...
Nithin E Paul +3 more
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Indonesian Journal of Cancer, 2017 Epithelial ovarian cancer is a deadly cancer, cancer recurrence and resistance post surgical staging and chemotherapy are major problems which will eventually occur in most advanced stage ovarian cancer.
PUNGKY MULAWARDHANA +2 more
doaj +1 more source
Drug Delivery, 2018 Glioma, one of the most common brain tumors, remains a challenge worldwide. Due to the specific biological barriers such as blood–brain barrier (BBB), cancer stem cells (CSCs), tumor associated macrophages (TAMs), and vasculogenic mimicry channels (VMs),
Liuqing Yang +8 more
doaj +1 more source
Aldehyde dehydrogenase 1 and CD44 serve as prognostic markers in patients with breast cancer
Annals of Medical Science and Research, 2022 Background and Objective: Breast cancer is the second leading cause of cancer-related death in women globally, and its prevalence is rising quickly, particularly in low- and middle-income nations.
Ayan Pradhan, Diptendra Kumar Sarkar
doaj +1 more source
Signaling through CD44 affects cell cycle progression and c-Jun expression in acute myeloid leukemia cells [PDF]
, 2004 We present here the first evidence linking CD44 signaling to c-Jun expression and cell cycle progression in myeloid cell line models. CD44 ligation with the anti-CD44 monoclonal antibodies have been shown to induce differentiation and inhibit the ...
Peer Zada, Abdul Ali
core +1 more source
Hyaluronic acid-coated niosomal sorafenib targets CD44 and suppresses NF‑κB signalling in oral squamous cell carcinoma [PDF]
Iranian Journal of Basic Medical SciencesObjective(s): Oral squamous cell carcinoma (OSCC) remains highly lethal and is driven, in part, by chronic NF-κB-mediated inflammation. Sorafenib, a multikinase inhibitor of RAF/VEGFR/PDGFR, can suppress these pathways, but its clinical utility is ...
Ting Wu +3 more
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The effect of hyaluronic acid on nucleus pulposus extracellular matrix production through hypoxia-inducible factor-1α transcriptional activation of CD44 under hypoxia [PDF]
European Cells & Materials, 2021 Intervertebral disc degeneration (IDD) is the leading cause of low-back pain. Implantation of hyaluronic acid (HA) is potentially a therapeutic strategy for IDD, but its pharmacological effects and mechanism under hypoxic conditions remain unclear.
F Zhang +7 more
doaj +1 more source
Cancer Management and Research, 2021 Cheng Xing, Yatong Li, Cheng Ding, Shunda Wang, Hanyu Zhang, Lixin Chen, Pengyu Li, Menghua Dai Department of General Surgery, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, 100730,
Xing C +7 more
doaj
CD44s and CD44v6 Expression in Head and Neck Epithelia [PDF]
, 2008 Background: CD44 splice variants are long-known as being associated with cell transformation. Recently, the standard form of CD44 (CD44s) was shown to be part of the signature of cancer stem cells (CSCs) in colon, breast, and in head and neck squamous ...
Olivier Gires +7 more
core +2 more sources