Results 21 to 30 of about 229,337 (378)
Mutant Allele of CD44 (rs8193C>T) and Pum2 Regulatory Element as A Prognosis Factor of Prostate Neoplasms: A Case-Control and In Silico Studies [PDF]
Cell Journal, 2022 ObjectiveExpression of CD44 variant 6 (CD44v6) as a homing-associated cell adhesion molecule (HCAM), hasproved to change most cancer cells. Aim of the study is the effect of mutant allele of CD44 (rs8193C>T) and Pum2regulatory element as a prognosis ...
Mohammadkazem Heydari +2 more
doaj +1 more source
CD44 is a prognostic biomarker and correlated with immune infiltrates in gastric cancer
BMC Medical Genomics, 2022 Objective Gastric carcinoma is the most common malignant tumour of the human digestive system worldwide. CD44 serves as a marker for several tumour stem cells, including gastric cancer.
Weiyan Hou +3 more
semanticscholar +1 more source
Omics, 2021 One of the most frequently utilized cancer stem cell markers in human cancers, including colorectal cancer and breast cancer, is CD44. A glycoprotein, CD44, traverses the cell membrane and binds to many ligands, including hyaluronan, resulting in ...
Kevin Dzobo, M. Sinkala
semanticscholar +1 more source
The effect of hyaluronic acid on nucleus pulposus extracellular matrix production through hypoxia-inducible factor-1α transcriptional activation of CD44 under hypoxia [PDF]
European Cells & Materials, 2021 Intervertebral disc degeneration (IDD) is the leading cause of low-back pain. Implantation of hyaluronic acid (HA) is potentially a therapeutic strategy for IDD, but its pharmacological effects and mechanism under hypoxic conditions remain unclear.
F Zhang +7 more
doaj +1 more source
Patologìâ, 2023 The aim of the study. Immunohistochemical study of Nestin, CD44, Ki-67, GS, AQP4 expression in the subventricular zone of the lateral ventricle and hippocampus of deceased patients with liver cirrhosis depending on the age and Child–Pugh score ...
T. V. Shulyatnikova, V. O. Tumanskiy
doaj +1 more source
Residual tumor cells that drive disease relapse after chemotherapy do not have enhanced tumor initiating capacity. [PDF]
, 2012 Although chemotherapy is used to treat most advanced solid tumors, recurrent disease is still the major cause of cancer-related mortality. Cancer stem cells (CSCs) have been the focus of intense research in recent years because they provide a possible ...
de la Cruz, Cecile +5 more
core +16 more sources
Journal of Radiation and Cancer Research, 2020 Background: Periampullary cancer (PC) is a global medical burden. Less than 5% of patients experience an overall survival of 5 years or more. The study aims to analyze the importance of epidermal growth factor receptor (EGFR)/insulin-like growth factor 1
Biswabandhu Bankura +4 more
doaj +1 more source
Cell Adhesion & Migration, 2021 We developed a computer-assisted platform using laser scanning confocal microscopy to 3D reconstruct in real-time interactions between metastatic breast cancer cells and human umbilical vein endothelial cells (HUVECs).
Deborah J. Wessels +13 more
doaj +1 more source
CD44 as a tumor biomarker and therapeutic target
Experimental Hematology & Oncology, 2020 CD44, a complex transmembrane glycoprotein, exists in multiple molecular forms, including the standard isoform CD44s and CD44 variant isoforms. CD44 participates in multiple physiological processes, and aberrant expression and dysregulation of CD44 ...
Hanxiao Xu +4 more
semanticscholar +1 more source
Rambam Maimonides Medical Journal, 2021 Objectives: To study the correlation between the putative cancer stem cell (CSC) markers aldehyde dehydrogenase 1 (ALDH1), cluster of differentiation 44 (CD44), sex-determining region Y-box 2 (SOX2), and octamer-binding protein 4 (OCT4) and human ...
Prasanth Thankappan +5 more
doaj +1 more source