CD44s and CD44v6 expression in head and neck epithelia. [PDF]
PLoS ONE, 2008 BACKGROUND: CD44 splice variants are long-known as being associated with cell transformation. Recently, the standard form of CD44 (CD44s) was shown to be part of the signature of cancer stem cells (CSCs) in colon, breast, and in head and neck squamous ...
Brigitte Mack, Olivier Gires
doaj +7 more sources
High Expression of Osteopontin and CD44v6 in Odontogenic Keratocysts [PDF]
Journal of the Formosan Medical Association, 2009 Odontogenic keratocysts (OKCs) are more aggressive and more osteolytic lesions than dentigerous cysts (DCs) and radicular cysts (RCs). Osteopontin (OPN) is related to cancer metastasis and bone destruction.
Yi-Ping Wang, Bu-Yuan Liu
doaj +6 more sources
Clinicopathological significance of fascin and CD44v6 expression in endometrioid carcinoma [PDF]
Diagnostic Pathology, 2012 Background Fascin and CD44v6 may have significant roles as biomarkers in tumour progression and metastasis. In endometrioid carcinomas, the fascin expression profile is less defined, and the significance of CD44v6 is uncertain.
Gun Banu +6 more
doaj +3 more sources
Clinical Significance of CD44s, CD44v3 and CD44v6 in Breast Cancer [PDF]
Journal of International Medical Research, 2015 Objectives: To evaluate levels of CD44 standard variant (CD44s), CD44 variant exon 3 (CD44v3) and CD44 variant exon 6 (CD44v6) protein in breast cancer tissue, and investigate their relationships with clinicopathological characteristics of the disease ...
Ning, Zhong-Hua +6 more
core +4 more sources
Expression of CD44s and CD44v6 in Lung Cancer and Their Correlation with Prognostic Factors
The International Journal of Biological Markers, 2011 Background CD44, a transmembrane glycoprotein receptor, plays a major role in tumor progression and metastasis. Objective: To evaluate the expression of CD44 standard (CD44s) and its variant 6 (CD44v6) in normal and neoplastic lung tissue and correlate ...
Alaa M. Afify MD +4 more
doaj +2 more sources
Involvement of CD44v6 in InlB-dependent Listeria invasion
Molecular Microbiology, 2009 Jung C, Matzke A, Niemann H, Schwerk C, Tenenbaum T, Orian-Rousseau V. Involvement of CD44v6 in InlB-dependent Listeria invasion. Molecular Microbiology.
Schwerk, C. +14 more
core +5 more sources
CD44v6+ Hepatocellular Carcinoma Cells Maintain Stemness Properties through Met/cJun/Nanog Signaling
Stem Cells International, 2022 Cancer stem cells (CSCs) are characterized by their self-renewal and differentiation abilities. CD44v6 is a novel CSC marker that can activate various signaling pathways.
Wei Chen +9 more
doaj +2 more sources
The role of CD44v6 in RTK internalization and trafficking [PDF]
, 2013 Internalization of receptor tyrosine kinases (RTKs) is crucial for RTK signaling and cellular responses such as cell migration. This work shows that CD44v6 mediates the internalization of the RTK Met and traffics together with Met through endosomal ...
Malinger, Dieter-Augustin
core +4 more sources
CD44/CD44v6 a Reliable Companion in Cancer-Initiating Cell Maintenance and Tumor Progression
Frontiers in Cell and Developmental Biology, 2018 Metastasis is the leading cause of cancer death, tumor progression proceeding through emigration from the primary tumor, gaining access to the circulation, leaving the circulation, settling in distant organs and growing in the foreign environment.
Zhe Wang +3 more
doaj +2 more sources
MicroRNA-135 alleviates cisplatin resistance in cervical cancer by inhibiting CD44v6
Pakistan Journal of Pharmaceutical SciencesBackground: Cervical cancer (CC) remains a leading cause of cancer-related mortality worldwide and cisplatin resistance poses a major challenge to effective treatment.
Rui Zhou +3 more
doaj +2 more sources