Results 101 to 110 of about 18,936 (283)
Cell Proliferation, EarlyView.Schematic representation of generation of 8‐gene‐edited cloned pigs and their verification by pig to non‐human primate kidney xenotransplantation. ABSTRACT Gene‐edited (GE) pig‐to‐human xenotransplantation continues to make breakthroughs, but which kind of gene combination is suitable for organ‐specific transplantation remains unclear.
Jiaoxiang Wang +23 more
wiley +1 more source
Journal of Immunology, 2019 T he classic pathogen-fighting functions of our microbe sensing systems, such as the TLRs, the Nod-like receptors, and several proteins of the complement system, had been defined relatively rapidly after their discovery (1, 2).
M. Liszewski, C. Kemper
semanticscholar +1 more source
Complexities in human herpesvirus-6A and -6B binding to host cells [PDF]
, 2006 Human herpesvirus-6A and -6B uses the cellular receptor CD46 for fusion and infection of the host cell. The viral glycoprotein complex gH–gL from HHV-6A binds to the short consensus repeat 2 and 3 in CD46. Although all the major isoforms of CD46 bind the
Höllsberg, Per, Pedersen, Simon Metz
core +1 more source
Cancer Cell International, 2021 Background To rummage autophagy-related prognostic, diagnostic, and therapeutic biomarkers in cervical cancer (CC). Methods The RNA-sequence and clinical information were from the TCGA and GTEx databases.
Dan Meng +10 more
doaj +1 more source
Adenovirus interactions with CD46 on transgenic mouse erythrocytes
Virology, 2010 Hemagglutination is an established method but has not been used previously to determine the efficacy of virus binding to a specific cellular receptor. Here we have utilized CD46-expressing erythrocytes from a transgenic mouse to establish whether and to what extent the species B adenoviruses (Ads) as well as Ad37 and Ad49 of species D can interact with
Ya-Fang Mei +2 more
openaire +3 more sources
CD46 signaling in T cells: Linking pathogens with polarity [PDF]
FEBS Letters, 2010 CD46 is a cell surface protein that regulates complement activity and is utilized as a receptor by numerous viral and bacterial pathogens that infect humans. CD46 is not just an entry site for pathogens, but can affect various cellular activities in response to pathogen binding that can have profound consequences for the host response to infection. The
Edwin D. Hawkins +2 more
openaire +3 more sources
The changing role of cell culture in the generation of transgenic livestock [PDF]
, 1999 Transgenesis may allow the generation of farm animals with altered phenotype, animal models for research and animal bioreactors. Although such animals have been produced, the time and expense involved in generating transgenic livestock and then ...
Farini, E, Webster, J, Whitelaw, C B
core +1 more source
PLoS ONE, 2012 Cell microparticles (MPs) released in the extracellular milieu can embark plasma membrane and intracellular components which are specific of their cellular origin, and transfer them to target cells.
Gaëlle Gonzalez +5 more
doaj +1 more source
Developmental Neurobiology, Volume 85, Issue 3, July 2025.ABSTRACT Reduced expression of the serotonin transporter (5‐hydroxytryptamine transporter, 5‐HTT) in early life has been associated with a delay in postnatal brain development and endophenotypes of a variety of neuropsychiatric and neurodevelopmental disorders in adolescence and adulthood.
Yvet Kroeze +9 more
wiley +1 more source
Targeting CD46 for both adenocarcinoma and neuroendocrine prostate cancer.
JCI Insight, 2018 Although initially responsive to androgen signaling inhibitors (ASIs), metastatic castration-resistant prostate cancer (mCRPC) inevitably develops and is incurable.
Yang Su +15 more
semanticscholar +1 more source