Results 151 to 160 of about 141,166 (348)
Absolute lymphocyte count: A cost-effective substitute to CD4 count in HIV positive patients [PDF]
, 2021 Ashish N Madiya +1 more
openalex +1 more source
Advanced Science, EarlyView.This study demonstrates that dual UCP2/IL‐17 blockade reprograms T‐cell metabolism to overcome PDAC immunosuppression. Genipin‐mediated UCP2 inhibition enhances CD8⁺ T‐cell IFN‐γ via IL‐12R/STAT4/mTOR signaling and mitochondrial OXPHOS. Combined IL‐17 depletion amplifies Tc1/Th1 responses, reduces MDSCs, and prolongs survival in PDAC models ...
Chuan‐Teng Liu +11 more
wiley +1 more source
The association between cigarette smoking, virologic suppression, and CD4+ lymphocyte count in HIV-Infected Russian women. [PDF]
AIDS Care, 2017 Brown JL +8 more
europepmc +1 more source
CD4 Percentages and Total Lymphocyte Counts as Early Surrogate Markers for Pediatric HIV-1 Infection in Resource-Limited Settings [PDF]
, 2006 François Rouet
openalex +1 more source
Advanced Science, EarlyView.This study presents a 3D lymphoid tissue model engineered from adipose‐derived stem cells differentiated into fibroblastic reticular cell–like networks and co‐cultured with immune cells. The engineered system successfully generates antigen‐specific antibodies and cytokine responses, providing a platform for studying adaptive immunity, vaccine efficacy,
Mei ElGindi, Shaza Karaman, Jeremy Teo
wiley +1 more source
Advanced Science, EarlyView.Lei et al. demonstrate that cancer stem cells (CSCs) play a pivotal role in impairing the differentiation of CD103+ T cells in patients with non‐small‐cell lung cancer. The key mechanism involves CSC‐derived acetyl‐CoA, which disrupts CD103+ T cell differentiation by sequentially inducing acetylation and ubiquitination of the Blimp‐1 protein. Targeting
Jiaxin Lei +10 more
wiley +1 more source
AntioxidantsScientific evidence has suggested, in most cases, that nullity of the GSTM1 and GSTT1 genes is associated with worse pathological outcomes and viral infections.
Marcela Gonçalves Trevisan +5 more
doaj +1 more source
Advanced Science, EarlyView.Solid predominant lung adenocarcinoma exhibits an immune‐excluded, ferroptosis‐resistant niche enriched with IL4I1⁺ TAMs and TDO2⁺ myCAFs. Spatial and multi‐omics analyses reveal AhR‐driven crosstalk that promotes T cell exhaustion and therapy resistance. Blocking AhR with CH‐223191 restores ferroptosis sensitivity, and its combination with ferroptosis
Zhaoxuan Wang +16 more
wiley +1 more source
Assessing the effect of traditional Chinese medicine on CD4+ lymphocyte count of 807 HIV/AIDS cases
, 2010 Jian Wang +8 more
openalex +2 more sources
Classification of Absolute Cd4+ T Lymphocytes Count in Immunological, Virological and Erythropoietic Growth Factor among HIV Infected Patients [PDF]
, 2022 Esan Ayodele Jacob +4 more
openalex +1 more source