Results 261 to 270 of about 293,060 (357)

Intrinsic metabolic and immune impairments in a genetic mouse model of schizophrenia. [PDF]

Schizophrenia (Heidelb)
Belmonte M, Cardoso SL, Di Pietro AA, Veigas F, Pasquini LA, Gelman DM.   +5 more
europepmc   +1 more source

Lipid metabolism reprograming by SREBP1‐PCSK9 targeting sensitizes pancreatic cancer to immunochemotherapy

Cancer Communications, EarlyView.
Abstract Background Pancreatic cancer's aberrant lipid metabolism fuels cell growth, invasion, and metastasis, yet its impact on immune surveillance and immunotherapy is unclear. This study investigated how sterol regulatory element‐binding transcription factor 1 (SREBP1)‐driven lipid metabolism affects the tumor microenvironment (TME) in pancreatic ...
Mengyi Lao, Xiaozhen Zhang, Zejun Li, Kang Sun, Hanshen Yang, Sicheng Wang, Lihong He, Yan Chen, Hanjia Zhang, Jiatao Shi, Daqian Xu, Tingbo Liang, Xueli Bai   +12 more
wiley   +1 more source

Immune System Alterations in the Development of Three Urological Cancers: Insights from Large-Sample Mendelian Randomization. [PDF]

Biomedicines
Chen Z, Xie Y, Chen X, Hong G, Shen R, Lin H, Jiang F, Wang Y, Zhu M, Liu Y, Wang H, Yang H, Lin T, Wu S.   +13 more
europepmc   +1 more source

NAT10 regulates tumor progression and immune microenvironment in pancreatic ductal adenocarcinoma via the N4‐acetylated LAMB3‐mediated FAK/ERK pathway

Cancer Communications, EarlyView.
Abstract Background N‐acetyltransferase 10 (NAT10) was reported to be associated with the immune microenvironment in several cancers. However, it is not known in pancreatic ductal adenocarcinoma (PDAC). This study aimed to elucidate the roles and mechanisms of NAT10 in tumor malignancy and the tumor microenvironment (TME) in PDAC.
Enhong Chen, Qin Wang, Leisheng Wang, Zebo Huang, Dongjie Yang, Changyong Zhao, Wuqiang Chen, Shuo Zhang, Shuming Xiong, Youzhao He, Yong Mao, Hao Hu   +11 more
wiley   +1 more source

Lupus nephritis association with idiopathic CD4 + T lymphocytopenia: a case report of a young man with recalcitrant warts. [PDF]

BMC Nephrol
Wang T, Liu S, Liang X, Xue J, You L, Zhu X.   +5 more
europepmc   +1 more source

Targeting SPHK1 in macrophages remodels the tumor microenvironment and enhances anti‐PD‐1 immunotherapy efficacy in colorectal cancer liver metastasis

Cancer Communications, EarlyView.
Abstract Background Colorectal cancer liver metastasis (CRLM) is characterized by an immunosuppressive microenvironment and a blunted response to immunotherapy. Notably, tumor‐associated macrophages (TAMs) play a critical role in modulating immune responses and exhibit significant heterogeneity in CRLM.
Yizhi Zhan, Jinsong Xu, Zhanqiao Zhang, Yating Hu, Yongsheng Li, Junying Qian, Yunyan Ling, Dehua Wu, Haijun Deng, Guoxin Li, Zhiyong Shen, Yuan Fang   +11 more
wiley   +1 more source

Associations of Lymphocyte Subpopulations, Related Cytokines, Clinical Phenotypes, and Outcomes in Systemic Juvenile Idiopathic Arthritis. [PDF]

ACR Open Rheumatol
Lerkvaleekul B, Sitthisarunkul N, Apiwattanakul N, Klinmalai C, Pongsakul N, Vilaiyuk S.   +5 more
europepmc   +1 more source

Assessing the effect of traditional Chinese medicine on CD4+ lymphocyte count of 807 HIV/AIDS cases

, 2010
Jian Wang, Wen Zou, Ying Liu, Liran Xu, Fang Lü, Yuguang Wang, Guoliang Zhang, Jiaming Lu, Jun Zhou   +8 more
openalex   +2 more sources

Promising Prodiginins Biological Activities

Chemistry &Biodiversity, EarlyView.
ABSTRACT Prodiginins are a large family of at least 34 pyrrolic compounds, including the well‐studied red pigment prodigiosin. Prodiginins are produced by several microorganisms displaying broad biological activities, including antimicrobial, antiviral, antiparasitic, antiproliferative, and immunosuppressive activities.
María F. Ladetto, Melisa E. Gantner, Boris E. Rodenak‐Kladniew, Santiago Rodriguez, María L. Cuestas, Alan Talevi, Guillermo R. Castro   +6 more
wiley   +1 more source

Diagnostic Efficacy and Clinical Significance of Lymphocyte Subsets, Granzyme B and Perforin in the Peripheral Blood of Patients with Invasive Breast Cancer Following Neoadjuvant Chemotherapy. [PDF]

Cancer Manag Res
Liu H, Zheng R, Zhuang Z, Xue L, Chen M, Wu Y, Zeng Y.   +6 more
europepmc   +1 more source