Results 301 to 310 of about 293,060 (357)

Effect of prevaccination blood and T-cell phenotypes on antibody responses to a COVID-19 mRNA vaccine. [PDF]

Int Immunol
Hidaka Y, Jo N, Kikuchi O, Fukahori M, Sawada T, Shimazu Y, Yamamoto M, Kometani K, Nagao M, Nakajima TE, Muto M, Morita S, Hamazaki Y.   +12 more
europepmc   +1 more source

Single‐Cell Transcriptomic Analysis of the Immune Response to COVID‐19 and Tuberculosis Coinfection

Exploration, EarlyView.
Understanding the immunological basis for severe outcomes in COVID‐19/Tuberculosis coinfection is critical. Our single‐cell analysis identifies key drivers: profound lymphocyte loss through combined apoptosis and altered trafficking, excessive S100 protein‐mediated inflammation contributing to cytokine storms, and systemic immune dysfunction ...
Yi Wang, Maike Zheng, Yun Zhang, Yu Xue, Sibo Long, Chaohong Wang, Qing Sun, Jun Yan, Yiheng Shi, Bin Yang, Shang Ma, Tiantian Zhang, Lei Cao, Yan Chen, Wenfu Ju, Jing Zhang, Yan Zhao, Mengqiu Gao, Laurence Don Wai Luu, Xinting Yang, Guirong Wang   +20 more
wiley   +1 more source

Immunological consequences of CAR T-cell therapy: an analysis of infectious complications and immune reconstitution. [PDF]

Blood Adv
Riedel A, Phely L, Hug S, Faustmann P, Schroeder JC, Besemer B, Paczulla Stanger AM, Faul C, Lengerke C, Weller JF, Bethge W.   +10 more
europepmc   +1 more source

MiR‐29a/b Suppresses CD8+ T Cell Effector Function and Intestinal Inflammation

Exploration, EarlyView.
Our findings suggest that miR‐29a/b is a critical regulator of CD8+ T cells, possibly via the Ifng‐JAK‐STAT signal in IBD patients and the upregulation of miR‐29a/b relieves the development of significant inflammation in the colon of DSS‐induced colitis‐affected mice.
Yingying Lin, Yuqi Wang, Yuning Zhang, Yao Lu, Juan Chen, Yongting Luo, Jian He, Qingfeng Luo, Heng Quan, Weiru Yu, Yujia Luo, Peng Xue, Yi Xue, Xiaoya Lin, Rui Ding, Lining Chen, Yiran Wang, Zenghui Xia, Liang Zhao, Hao Zhang, Ran Wang, Qingyu Wang, Xifan Wang, Jiaqi Su, Fazheng Ren, Cong Lv, Yixuan Li, Huiyuan Guo   +27 more
wiley   +1 more source

Variation in Immune and Inflammatory Blood Markers in Advanced Melanoma Patients Treated with PD-1 Inhibitors: A Preliminary Exploratory Study. [PDF]

Biomedicines
Bolovan LM, Panait ME, Busca A, Stanciu AE, Chiriac D, Mihalcea CE, Hotnog CM, Georgescu MT, Voinea SC, Prunoiu VM, Brasoveanu LI, Gales LN.   +11 more
europepmc   +1 more source

Immunomodulatory Nanozymes Eradicate Intracellular Infections and Rescue Immunoparalysis for Treating Multidrug‐Resistant Bacterial Sepsis

Exploration, EarlyView.
Immunomodulatory nanozymes enable in situ macrophages engineering and orchestrate systemic innate‐adaptive immune response to eradicate intracellular bacteria and rescue immunoparalysis for treating multidrug‐resistant bacterial sepsis. ABSTRACT Sepsis and their sequelae are the leading causes of death in intensive care units, with limited therapeutic ...
Xuancheng Du, Zhenzhen Dong, Yan Yan, Yuan Gong, Meili Yuan, Chengtai Ma, Lingqi Xu, Yuanyuan Qu, Minhan Qu, Peng Pan, Weifeng Li, Wenyan Hao, Yingyi Yang, Xiangdong Liu, Mingwen Zhao, Zhenjiang Bai, Jiang Huai Wang, Jian Wang, Yong‐Qiang Li, Huiting Zhou   +19 more
wiley   +1 more source

Clinical Characteristics and Mortality Risk Factors in Patients with Tuberculosis and Coincident <i>Pneumocystis jirovecii</i> Pneumonia: A Retrospective Single-Center Study. [PDF]

Infect Drug Resist
Pan X, Zheng J, Xu J, Pan L, Wang C, Huang X, Qiu J, Yan C, Mao M.   +8 more
europepmc   +1 more source

Immune cell phenotypes as causal factors in liver disease progression revealed by Mendelian randomization. [PDF]

Sci Rep
Huang J, Zou W, Lv Z, Han H, Huang J, Su H.   +5 more
europepmc   +1 more source

Association of HIV low-level viremia with CD4 count recovery among persons living with HIV during antiretroviral therapy in Dehong Prefecture, Southwest China in 2008-2021: a longitudinal study. [PDF]

BMC Infect Dis
Yu H, Yang Y, Cao D, Cao Y, Shi Y, Xiao G, Li P, Feng Y, Wei H, Sun J, Duan S, Ye R, Jin C.   +12 more
europepmc   +1 more source

β-Actin Deficiency in Baraitser-Winter Syndrome Type 1 Disrupts T-Cell Function and Immune Regulation: Implications for Targeted Therapy in Actinopathies. [PDF]

J Clin Immunol
Bar-On Z, Reuven O, Lev A, Simon AJ, Salaymeh W, Shalom A, Somech R, Barel O, Porges S, Javasky E, Molho-Pessach V, Granot Z, Bijaoui D, Neuman T, Tal Y, Baniyash M, Berger M, Shamriz O.   +17 more
europepmc   +1 more source