A unified multimodal single-cell framework reveals a discrete state model of hematopoiesis in mice. [PDF]
Ferchen K +15 more
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Aging-Associated CD55⁺ Fibroblasts Promote Chronic Inflammation and ECM Dysregulation in Sarcopenia. [PDF]
Xie X +9 more
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Immune-mediated mechanisms and maternal-fetal interface dysfunction in obstetric antiphospholipid syndrome. [PDF]
Ma G, Han J, Gao R, Qin L.
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Genetically modified pigs with α1,3-galactosyltransferase knockout and beyond: a comprehensive review of xenotransplantation strategies. [PDF]
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Evaluation of Storage Stability of Date Fruit (<i>Phoenix dactylifera</i> L.) at Two Levels of Relative Humidity Based on Selected Functional Compounds and Image Features. [PDF]
Noutfia Y +6 more
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Structural studies of CD55 interactions with human proteins
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CD55 in cancer: Complementing functions in a non-canonical manner
Cancer Letters, 2022CD55, or decay accelerating factor, is a membrane lipid microdomain-associated, GPI-anchored protein implicated in the shielding of cells from complement-mediated attack via accelerating decay of C3 and C5. Loss of CD55 is associated with a number of pathologies due to hyperactivation of the complement system.
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Sialylation of CD55 by ST3GAL1 Facilitates Immune Evasion in Cancer
Cancer Immunology Research, 2021Abstract Altered glycosylations, which are associated with expression and activities of glycosyltransferases, can dramatically affect the function of glycoproteins and modify the behavior of tumor cells. ST3GAL1 is a sialyltransferase that adds sialic acid to core 1 glycans, thereby terminating glycan chain extension.
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