Single-nucleus transcriptional and chromatin accessibility analyses of maturing mouse Achilles tendon uncover the molecular landscape of tendon stem/progenitor cells [PDF]
eLifeTendons and ligaments are crucial connective tissues linking bones and muscles, yet achieving full functional recovery after injury remains challenging.
Hiroki Tsutsumi +8 more
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CD55 may be a new target for colorectal cancer treatment [PDF]
Scientific ReportsIn the early stage, our research group injected lentivirus carrying blood type A antigen into tumors as a drug, and the tumor volume of mice was significantly reduced. We speculate that the complement system plays an important role in anti-tumor therapy,
Qiong Luo +7 more
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EBV-induced upregulation of CD55 reduces the efficacy of cetuximab treatment in nasopharyngeal carcinoma [PDF]
Journal of Translational MedicineCetuximab, an anti-epidermal growth factor receptor (EGFR) antibody, has been shown to improve survival in nasopharyngeal carcinoma (NPC) patients. However, a correlation between the expression of EGFR and the response to cetuximab has not been observed,
Qian Zhu +7 more
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CD13 is a bona-fide marker of bovine pre-adipocytes with potential in cultivated fat applications [PDF]
npj Science of FoodDespite its significant potential, cultivated fat manufacture remains a relatively inefficient process, as it primarily uses source preparations of animal-derived mesenchymal stem/stromal cells (MSC) that are poorly defined and highly heterogenous in ...
Seungmee Lee +4 more
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CD55 Facilitates Immune Evasion by Borrelia crocidurae, an Agent of Relapsing Fever
mBio, 2022 Relapsing fever, caused by diverse Borrelia spirochetes, is prevalent in many parts of the world and causes significant morbidity and mortality. To investigate the pathoetiology of relapsing fever, we performed a high-throughput screen of Borrelia ...
Gunjan Arora +9 more
doaj +1 more source
Expression of the activation antigen CD97 and its ligand CD55 in rheumatoid synovial tissue [PDF]
Arthritis & Rheumatism, 1999 Fibroblast-like synoviocytes (FLS) express decay-accelerating factor (CD55) at high levels. Recently, it was found that CD55 is a specific cellular ligand for the 7-span transmembrane receptor CD97. The objective of this study was to define the expression of this receptor-ligand pair in synovial tissue (ST) to provide more insight into the interaction ...
Hamann, J. [=Jörg] +5 more
openaire +3 more sources
Antigen‐presenting cell exosomes are protected from complement‐mediated lysis by expression of CD55 and CD59 [PDF]
European Journal of Immunology, 2003 AbstractExosomes are secreted nanometer‐sized vesicles derived from antigen‐presenting cells, which have attracted recent interest as they likely play important roles in immune regulation, and their use as cell‐free tools for immunotherapy has been proposed.
Aled, Clayton +4 more
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Scientific Reports, 2022 Pig-to-human organ transplantation is a feasible solution to resolve the shortage of organ donors for patients that wait for transplantation. To overcome immunological rejection, which is the main hurdle in pig-to-human xenotransplantation, various ...
Nayoung Ko +9 more
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Cromer-related blood group antigens and the glycosyl phosphatidylinositol-linked protein, decay-accelerating factor DAF (CD55) [PDF]
Immunohematology, 1990 Abstract Cromer-related blood group antigens are located on the complement regulatory glycoprotein, decay-accelerating factor (DAF). DAF is not detectable on red cells from individuals with a Cromer null phenotype (termed Inab), which is probably an inherited condition.
openaire +2 more sources
Function of complement regulatory proteins in immunity of reproduction: a review
Czech Journal of Animal Science, 2005 Humoral immunity has an important role during the maturation and development of the functional properties of spermatozoa. Spermatozoa may be exposed to antisperm antibodies in semen and in cervical, ovarian follicular and fallopian fluid.
J. Valentovičová +2 more
doaj +1 more source