Results 1 to 10 of about 9,279 (174)
KLF4 and CD55 expression and function depend on each other
Frontiers in ImmunologyThe transcription factor Kruppel-like factor 4 (KLF4) regulates the expression of immunosuppressive and anti-thrombotic proteins. Despite its importance in maintaining homeostasis, the signals that control its expression and the mechanism of its ...
Edward Medof +2 more
exaly +5 more sources
The genetic and epigenetic regulation of CD55 and its pathway analysis in colon cancer
Frontiers in Immunology, 2023 BackgroundCD55 plays an important role in the development of colon cancer. This study aims to evaluate the expression of CD55 in colon cancer and discover how it is regulated by transcriptional factors and miRNA.MethodsThe expression of CD55 was explored
Zhenbang Yang +2 more
exaly +3 more sources
CD55 may be a new target for colorectal cancer treatment [PDF]
Scientific ReportsIn the early stage, our research group injected lentivirus carrying blood type A antigen into tumors as a drug, and the tumor volume of mice was significantly reduced. We speculate that the complement system plays an important role in anti-tumor therapy,
Qiong Luo +7 more
doaj +4 more sources
CD55 is over-expressed in the tumour environment [PDF]
British Journal of Cancer, 2001 CD55 is a protein that protects cells from complement-mediated attack. 791Tgp72 is an antigen which has been used successfully as a target for both tumour imaging and cancer vaccines. 791Tgp72 has recently been identified as CD55. Quantitative expression of CD55 in the tumour environment was therefore studied.
L G Durrant, Durrant L G
exaly +3 more sources
Erythrocyte CD55 mediates the internalization of Plasmodium falciparum parasites
eLife, 2021 Invasion of human erythrocytes by the malaria parasite Plasmodium falciparum is a multi-step process. Previously, a forward genetic screen for P. falciparum host factors identified erythrocyte CD55 as essential for invasion, but its specific role and how
Bikash Shakya +3 more
doaj +3 more sources
Neoplasia, 2006 Decay-accelerating factor (CD55) is a member of membrane-bound complement-regulatory proteins. CD55 expression correlates with poor survival in patients with colorectal cancer and has been implicated in the survival and tumorigenesis of blood-borne ...
Kenneth Pienta +2 more
exaly +3 more sources
Proteogenomic characterization of cholangiocarcinoma
Hepatology, EarlyView., 2022 Proteogenomic characterization of cholangiocarcinoma with therapeutic strategies Abstract Background and Aims Cholangiocarcinoma (CCA) is a highly heterogeneous cancer with limited understanding and few effective therapeutic approaches. We aimed at providing a proteogenomic CCA characterization to inform biological processes and treatment ...
Mengjie Deng +18 more
wiley +1 more source
Biomedicines, 2023 Recent studies utilizing single-cell analysis have unveiled the presence of various fibroblast (Fb) subsets within the synovium under inflammatory conditions in osteoarthritis (OA), distinguishing them from those in rheumatoid arthritis (RA).
Maho Tsuchiya +11 more
doaj +1 more source
Scientific Reports, 2023 Complement-dependent cytotoxicity (CDC), which eliminates aberrant target cells through the assembly and complex formation of serum complement molecules, is one of the major effector functions of anticancer therapeutic antibodies.
Sang Min Lee +10 more
doaj +1 more source
CD55 Facilitates Immune Evasion by Borrelia crocidurae, an Agent of Relapsing Fever
mBio, 2022 Relapsing fever, caused by diverse Borrelia spirochetes, is prevalent in many parts of the world and causes significant morbidity and mortality. To investigate the pathoetiology of relapsing fever, we performed a high-throughput screen of Borrelia ...
Gunjan Arora +9 more
doaj +1 more source