Results 21 to 30 of about 9,279 (174)
1,25-Dihydroxyvitamin D3 promotes a sustained LPS-induced NF-κB-dependent expression of CD55 in human monocytic THP-1 cells. [PDF]
PLoS ONE, 2012 The vitamin D3 system imposes immunosuppressive effects on monocytic cells, in part, by inhibiting NF-κB-dependent expression of proinflammatory mediators.
Michael G Izban +2 more
doaj +1 more source
Constitutive HO-1 and CD55 (DAF) Expression and Regulatory Interaction in Cultured Podocytes
Biomedicines, 2023 Overexpression of the inducible heme oxygenase (HO-1) isoform in visceral renal glomerular epithelial cells (podocytes) using in vivo transgenesis methods was shown to increase glomerular expression of the complement regulatory protein decay-accelerating
Elias A. Lianos +4 more
doaj +1 more source
Loss of CD55 Is Associated with Aggressive Breast Tumors [PDF]
Clinical Cancer Research, 2004 Abstract Purpose: CD55 is a complement regulatory protein expressed by cells to protect them from bystander attack by complement. CD55 is overexpressed on some tumor cell lines, and in colorectal carcinomas, it has been shown to be an indicator of poor prognostic.
Madjd, Zahra +5 more
openaire +3 more sources
Viruses, 2021 The human complement system is an important part of the innate immune system. Its effector pathways largely mediate virus neutralization. Vesicular stomatitis virus (VSV) activates the classical pathway of the complement, leading to virus neutralization ...
Nisha Asok Kumar +6 more
doaj +1 more source
Overexpression of Human CD55 and CD59 or Treatment with Human CD55 Protects against Renal Ischemia-Reperfusion Injury in Mice [PDF]
The Journal of Immunology, 2017 Abstract Deficiency in the membrane-bound complement regulators CD55 and CD59 exacerbates renal ischemia-reperfusion injury (IRI) in mouse models, but the effect of increasing CD55 and CD59 activity has not been examined. In this study, we investigated the impact of overexpression of human (h) CD55 ± hCD59 or treatment with soluble ...
Anjan K Bongoni +8 more
openaire +2 more sources
Early and extensive CD55 loss from red blood cells supports a causal role in malarial anaemia
Malaria Journal, 2011 Background Levels of complement regulatory proteins (CrP) on the surface of red blood cells (RBC) decrease during severe malarial anaemia and as part of cell ageing process.
Gwamaka Moses +3 more
doaj +1 more source
Journal of VirologyEnteroviruses cause nearly 1 billion global infections annually and are associated with a diverse array of human illnesses. Among these, myocarditis and the resulting chronic inflammation have been recognized as major contributing factors to virus ...
Yasir Mohamud +6 more
doaj +1 more source
PLoS ONE, 2013 BackgroundAn outbreak of Shiga Toxin 2 (Stx-2) producing enterohemorrhagic and enteroaggregative E.coli (EAHEC) O104H4 infection in May 2011 caused enterocolitis and an unprecedented high 22% rate of hemolytic uremic syndrome (HUS).
Werner Dammermann +8 more
doaj +1 more source
Advanced Functional Materials, EarlyView.A swelling‐programmed micropatterned hydrogel guides adherent cells through a controlled transition from cell–matrix anchoring to cadherin‐mediated cell–cell compaction, enabling rapid assembly of high‐viability spheroids with defined size and morphology.
Han Gyeol Nam +8 more
wiley +1 more source
A novel role for CD55 in granulocyte homeostasis and anti-bacterial host defense.
PLoS ONE, 2011 BackgroundIn addition to its complement-regulating activity, CD55 is a ligand of the adhesion class G protein-coupled receptor CD97; however, the relevance of this interaction has remained elusive. We previously showed that mice lacking a functional CD97
Henrike Veninga +8 more
doaj +1 more source