Results 101 to 110 of about 68,812 (293)
Novel Bispecific Engagers Targeting the CεmX Domain of mIgE‐Expressing Cells
Allergy, EarlyView.We developed bispecific TCE & NKCE targeting the CεmX domain of mIgE to eliminate IgE‐producing cells. Both constructs demonstrated potent, specific, dose‐dependent cytotoxicity and selective immune activation in vitro. These results highlight their promise as off‐the‐shelf, potentially curative therapeutics for IgE‐associated allergic diseases ...
Constantin Möller +16 more
wiley +1 more source
British Journal of Haematology, EarlyView.Summary Patients with immune thrombocytopenia (ITP) exhibit substantial heterogeneity in treatment responses. Approximately 30%–50% of patients maintain remission after discontinuation of thrombopoietin receptor agonists (TPO‐RA), suggesting immunomodulatory effects beyond enhanced thrombopoiesis.
Vivianne S. Nelson +5 more
wiley +1 more source
Expression of CD56 in NK cell clones.
, 2018 (A) The expression level of CD56 in NK cell clones obtained from different subsets analyzed 5 weeks after the beginning of cultivation (MFI mean ± SE). (B) CD56 surface expression in a NK cell clone from CD56dimHLA-DR−subset measured at weeks 3 and 5 of ...
William G. Telford (253706) +6 more
core +1 more source
Brain Pathology, EarlyView.Resource level‐based recommendations on practical diagnostic strategies for medulloblastomas and other CNS embryonal tumors are provided. Abstract WHO CNS5 mandates integrated histo‐molecular classification of medulloblastomas (MBs) and other CNS embryonal tumors. However, advanced molecular diagnostics remain inaccessible in many low‐ and lower‐middle‐
Chitra Sarkar +12 more
wiley +1 more source
Lymphomatoid Papulosis Type E With T-Cell Receptor Gamma Positivity
Clinical, Cosmetic and Investigational DermatologyAmornrut Namasondhi,1 Suthinee Rutnin,1 Suthep Jerasutus,1 Paisarn Boonsakan,2 Korn Triyangkulsri1 1Division of Dermatology, Department of Medicine, Faculty of Medicine, Ramathibodi Hospital, Mahidol University, Bangkok, Thailand; 2Department of ...
Namasondhi A +4 more
doaj
To be or not to be: the role of CD56 in multiple myeloma
Oncotarget, 2023 Cottini, Francesca, Benson, Don
openaire +2 more sources
Therapeutic potential of natural products in cancer immunotherapy: Advances and challenges
British Journal of Pharmacology, EarlyView.This review systematically outlines the mechanisms underlying tumour immunotherapy resistance and elucidates the role of natural products in enhancing therapeutic efficacy as immunomodulatory adjuvants. Abstract Immunotherapy has emerged as a clinically pivotal approach in cancer treatment, but its application remains limited to a small subset of ...
Rao Hu +6 more
wiley +1 more source
Cancer Science, EarlyView.We generated cord blood‐derived FAP‐targeted CAR NK cells and evaluated their activity against cancer‐associated fibroblasts. These cells showed antigen‐specific cytotoxicity in vitro and robust persistence in a pleural dissemination model, although in vivo anti‐CAF efficacy was limited, supporting further development of stromal‐targeted cellular ...
Takashi Hiroshima +14 more
wiley +1 more source
CD56 for Multiple Myeloma: Lack of CD56 May Be Associated with Worse Prognosis [PDF]
Acta Haematologica, 2018 Kanji Miyazaki, Kenshi Suzuki
openaire +2 more sources
Comparison of CD8 and CD56 cellular grades.
, 2016 Comparison of CD8 and CD56 cellular grades.
Philip J. Luthert (2806897) +12 more
core +1 more source