Results 91 to 100 of about 68,812 (293)

A novel population of CD4+CD56+ myelin-reactive T cells lyses target cells expressing CD56/neural cell adhesion molecule

, 1996
CD56 is a member of the neural cell adhesion molecule family expressed on cells of the central nervous system and also on NK cells. Previous studies suggest the involvement of CD56 in effector-to-target cell conjugation mediated by NK cells. It was shown
Dhib-Jalbut, S., Martin, R., Le, H., Vergelli, M., Noort, J.M. van, McFarland, H.   +5 more
core  

Exhausted CD56+ CD8 T lymphocytes in treated HIV infection.

, 2014
The expression of Tim-3 on T cells identified exhausted T lymphocytes. (A) A higher proportion of CD56+ CD8 T cells express Tim-3 compared to the CD56- subset.
C. David Pauza (358594), Bhawna Poonia (358592)   +1 more
core   +1 more source

Navigating the Complexity: A Comprehensive Review of GSK‐3 Inhibition in Regenerative Medicine

Medicinal Research Reviews, EarlyView.
ABSTRACT Glycogen synthase kinase‐3 (GSK‐3) is a central regulator of numerous cellular signaling pathways, with critical roles in metabolism, proliferation, differentiation, and tissue regeneration. This review explores the multifaceted effects of pharmacological GSK‐3 inhibition across multiple body districts, focusing on its highly context‐dependent
Davide Schiroli, Alessia Merra, Chiara Marraccini, Lucia Merolle, Graziella Pellegrini, Eleonora Maurizi   +5 more
wiley   +1 more source

Chemokine Receptor Expression on Normal Blood CD56+ NK-Cells Elucidates Cell Partners That Comigrate during the Innate and Adaptive Immune Responses and Identifies a Transitional NK-Cell Population

Journal of Immunology Research, 2015
Studies of chemokine receptors (CKR) in natural killer- (NK-) cells have already been published, but only a few gave detailed information on its differential expression on blood NK-cell subsets.
Margarida Lima, Magdalena Leander, Marlene Santos, Ana Helena Santos, Catarina Lau, Maria Luís Queirós, Marta Gonçalves, Sónia Fonseca, João Moura, Maria dos Anjos Teixeira, Alberto Orfao   +10 more
doaj   +1 more source

Infantile CD4+/CD56+ hematodermic neoplasm

Haematologica, 2007
CD4+/CD56+ hematodermic neoplasm (formerly known as blastic natural killer (NK) cell lymphoma) is a rare and aggressive neoplasm with a poor prognosis. It is a recently described entity with a predilection for skin involvement.[1][1] Previously, the disease was thought to originate from NK ...
Stephen Chu-Sung Hu, Kun-Bow Tsai, Gwo-Shing Chen, Po-Hung Chen   +3 more
openaire   +3 more sources

Immunomodulatory Properties of Withania somnifera: Regulation of Innate Immune Cells and Clinical Implications

Phytotherapy Research, EarlyView.
ABSTRACT Withania somnifera (L.) Dunal (WS), commonly known as Ashwagandha, is a prominent medicinal herb in Ayurveda, with extensive therapeutic potential attributed to its diverse phytochemical profile. This review critically examines the immunomodulatory properties of WS, focusing on innate immune cell populations, including neutrophils, eosinophils,
Rana Yukta, Sonalika Gupta, Gagandeep Kaur, Partha Sarathi Mondal, Milirani Das, Anagha Ranade, Alok Kumar Srivastava, Sachin Kumar, Manoj Kumar Barthwal, Madhu Dikshit   +9 more
wiley   +1 more source

Quantitative Imaging of Human Hemoglobin Binding to Staphylococcus aureus With Single‐Molecule Resolution

Small, EarlyView.
Single‐molecule localization microscopy is exploited to quantify the number of hemoglobin copies bound to specific receptors on S. aureus wall. This quantification supports the design of a photoactive derivative of hemoglobin able to photo‐inactivate S.
Pietro Delcanale, Andrea Mussini, Òscar Gulías, Montserrat Agut, Melissa Berni, Stefano Pongolini, Stefano Bruno, Alessandro Casnati, Santi Nonell, Cristiano Viappiani, Stefania Abbruzzetti   +10 more
wiley   +1 more source

immunoHuMiX: A personalizable gut‐on‐chip model for unraveling human microbiome–immune interactions

VIEW, EarlyView.
The study introduces a personalized gut model that brings together human immune cells and intestinal cells to better mimic how the body interacts with microbes. This system successfully maintained both human cells and a 17‐strain probiotic community, showing consistent immune responses across different donors.
Charlotte De Rudder, Kacy Greenhalgh, Joanna Baginska, Camille Martin‐Gallausiaux, Léa Grandmougin, Rémy Villette, Mara Lucchetti, Bérénice Hansen, Marek Ostaszewski, Viacheslav A. Petrov, Koji Atarashi, Lena Weidert, Audrey Frachet Bour, Dominik Ternes, Javier Ramiro‐Garcia, Antoine Malabirade, Takeshi Tanoue, Marc Mac Giolla Eain, Elisabeth Letellier, Matthew Barrett, Jérôme Lacombe, Frederic Zenhausern, Coralie Guérin, Markus Ollert, Carole Seguin‐Devaux, Kenya Honda, Paul Wilmes   +26 more
wiley   +1 more source

Phenotypic and functional analyses of NK and NKT-like populations during the early stages of chikungunya infection

Frontiers in Microbiology, 2015
The aim of this study was to characterize NK (CD56+CD3−) and NKT-like cell (CD56+CD3+) responses early after chikungunya infection. Expression profiling and functional analysis of T/NK/NKT-like cells were performed on samples from 56 acute and 31 ...
Subrat eThanapati, Rumki eDas, Anuradha S Tripathy   +2 more
doaj   +1 more source

Advances in γδ T Cells: Cutaneous Biology and Therapeutic Potential for Skin Neoplasms

The Journal of Dermatology, EarlyView.
ABSTRACT γδ T cells represent an increasingly important subset of T lymphocytes in the immune response to cancer and as a platform for novel immunotherapies. The aim of this review is to synthesize recent insights into the biology and advances in therapeutic applications of γδ T cells in cutaneous malignancies, especially melanoma, within a framework ...
Simo Du, Anika Jallorina, Toru Yoshino, Lingyu Bao, Han Bao, Victor Chang, Henry K. Wong, Derek V. Chan, Stephen K. Richardson, Mary F. Lee‐Wong   +9 more
wiley   +1 more source