Results 81 to 90 of about 447,008 (222)

A Case of Blastic Plasmacytoid Dendritic Cell Neoplasm Extensively Studied by Flow Cytometry and Immunohistochemistry

Case Reports in Hematology, 2017
Blastic plasmacytoid dendritic cell neoplasm (BPDCN) is a rare hematologic malignancy with aggressive clinical course and poor prognosis. Diagnosis is based on detection of CD4+ CD56+, CD123high, TCL-1+, and blood dendritic cell antigen-2/CD303+ blasts ...
Martina Pennisi, Clara Cesana, Micol Giulia Cittone, Laura Bandiera, Barbara Scarpati, Valentina Mancini, Silvia Soriani, Silvio Veronese, Mauro Truini, Silvano Rossini, Roberto Cairoli   +10 more
doaj   +1 more source

EFFECTS OF COMBINED PHYSIOTHERAPY IN CHRONIC ENDOMETRITIS: DYNAMICS OF INFLAMMATORY ACTIVITY

Медицинская иммунология, 2015
We have performed immunohistochemical staining of lymphocyte subpopulations (CD16+, CD56+, CD20+, CD138+), and HLA-DR antigen (II class) using monoclonal antibodies by “Novocastra” (United Kingdom).
M. P. Рlyasunova, S. V. Chlybova, A. A. Feoktistov, V. I. Shardakov   +3 more
doaj   +1 more source

Increased anergic B cells and decreased antibody‐secreting cells during romiplostim treatment in patients with immune thrombocytopenia

British Journal of Haematology, EarlyView.
Summary Patients with immune thrombocytopenia (ITP) exhibit substantial heterogeneity in treatment responses. Approximately 30%–50% of patients maintain remission after discontinuation of thrombopoietin receptor agonists (TPO‐RA), suggesting immunomodulatory effects beyond enhanced thrombopoiesis.
Vivianne S. Nelson, Rebeca Gutiérrez‐Cózar, Rebecca Cornelis, S. Marieke van Ham, Anja ten Brinke, Rick Kapur   +5 more
wiley   +1 more source

Comparison of RCAS1 and metallothionein expression and the presence and activity of immune cells in human ovarian and abdominal wall endometriomas

Reproductive Biology and Endocrinology, 2006
Background The coexistence of endometrial and immune cells during decidualization is preserved by the ability of endometrial cells to regulate the cytotoxic immune activity and their capability to be resistant to immune-mediated apoptosis.
Lazar Agata, Popiela Tadeusz, Banas Tomasz, Galazka Krystyna, Dutsch-Wicherek Magdalena, Wicherek Lukasz, Kleinrok-Podsiadlo Beata   +6 more
doaj   +1 more source

Interferon-α-Induced Dendritic Cells Generated with Human Platelet Lysate Exhibit Elevated Antigen Presenting Ability to Cytotoxic T Lymphocytes

Vaccines, 2020
Given the recent advancements of immune checkpoint inhibitors, there is considerable interest in cancer immunotherapy provided through dendritic cell (DC)-based vaccination.
Ippei Date, Terutsugu Koya, Takuya Sakamoto, Misa Togi, Haruhiko Kawaguchi, Asuka Watanabe, Tomohisa Kato, Shigetaka Shimodaira   +7 more
doaj   +1 more source

Primary small cell carcinoma of the esophagus: clinicopathological and immunohistochemical features of 21 cases

BMC Cancer, 2007
Background Primary small cell carcinoma (SCC) of the esophagus is a rare and aggressive tumor with poor prognosis. In this study, we report the clinicopathological characteristics of 21 cases of small cell carcinoma of the esophagus treated at the Cancer
Tian Qiu-Hong, Hou Jin-Hui, Zhang Mei-Fang, Yun Jing-Ping, Fu Jia, Liang Xiao-Man, Wu Qiu-Liang, Rong Tie-Hua   +7 more
doaj   +1 more source

Therapeutic potential of natural products in cancer immunotherapy: Advances and challenges

British Journal of Pharmacology, EarlyView.
This review systematically outlines the mechanisms underlying tumour immunotherapy resistance and elucidates the role of natural products in enhancing therapeutic efficacy as immunomodulatory adjuvants. Abstract Immunotherapy has emerged as a clinically pivotal approach in cancer treatment, but its application remains limited to a small subset of ...
Rao Hu, Kaibin Dai, Zhensheng Lin, Mingfang Ye, Minfeng Chen, Xiaobo Li, Dongmei Zhang   +6 more
wiley   +1 more source

Ovarian Cancer-Associated Ascites Accumulates NK Lymphocytes Displaying a Transcriptomic Profile Consistent With the Immature/Secretory CD56^bright Subtype. [PDF]

Immunol Cell Biol
NK cells present in EOC‐associated ascites retain elements of the conventional NK cell program while displaying a transcriptional profile distinct from peripheral blood NK cells. This profile encompasses biological programs usually associated with the CD56bright NK cell functions, which is consistent with transcriptional remodeling rather than complete
de Souza-Araújo CN, Baptista G, Guimarães GR, da Silva RCA, Yoshida A, Tonetti CR, Yunes JA, Cardoso DM, Derchain S, Boroni M, Guimarães F.   +10 more
europepmc   +2 more sources

Primary Cutaneous Gamma‐Delta T‐Cell Lymphoma Complicating Long‐Standing Immunosuppressed Dermatomyositis

Journal of Cutaneous Pathology, EarlyView.
ABSTRACT Primary cutaneous gamma‐delta T‐cell lymphoma (PCGD‐TCL) is a rare cytotoxic lymphoma with key oncogenic drivers in the JAK/STAT pathway. Also primarily involving the subcutaneous adipose tissue, subcutaneous panniculitis‐like T‐cell lymphoma (SPTCL) is more frequently encountered in scenarios of autoimmune disorders.
Bennett Christie‐Nguyen, Youn H. Kim, David F. Fiorentino, Danielle Tartar, Ryanne Brown, Robert A. Novoa, Kerri E. Rieger   +6 more
wiley   +1 more source

Adverse outcome of AML with aberrant CD16 and CD56 NK cell marker expression. [PDF]

, 2018
Natural killer cells mediate antibody-dependent cell-mediated cytotoxicity, and CD16 exerts key functions to induce antibody-dependent cell-mediated cytotoxicity response.
Pabst Müller, Thomas Niklaus, Mueller, Beatrice U, Beatrice U. Mueller, Solenthaler, Max, Thomas Pabst, Keller, Peter, Peter Keller, Max Solenthaler, Bacher, Vera Ulrike, Junge, Alexandra, Ulrike Bacher, Alexandra Junge   +11 more
core   +1 more source