Results 151 to 160 of about 34,015 (256)

Pomalidomide significantly enhances the antitumor immune efficacy of dendritic cell-derived exosomes from multiple myeloma patients. [PDF]

J Transl Med
Zhang H, Wang Y, Wang X, Duan H, Yu D, Kuang X, He L, Zhang W, Chen J, Dai J.   +9 more
europepmc   +1 more source

Extracellular vesicles in pharmacology: Innovations in drug delivery and therapeutic applications in cancer

British Journal of Pharmacology, EarlyView.
Extracellular vesicles (EVs) are a diverse population of membrane nanoparticles secreted by nearly all cell types, playing a key role in intercellular communication by transferring bioactive macromolecular cargo. In cancer, EVs shape both the local tumour microenvironment and distant premetastatic niches.
Evangelia Pantazaka, Georgios Sivvas, Evangelia Papadimitriou, Constantinos M. Mikelis   +3 more
wiley   +1 more source

Polymeric α‐Hairpinin Allergens Induce a Functional Response via a Single Antibody

Allergy, EarlyView.
Gage O. Leighton, Taylor M. Cosey, Emmanuel R. De Diavoukana, Isabelle R. Lytle, Alexander C. Y. Foo, Lars C. Pedersen, Scott A. Gabel, Robert M. Petrovich, Min Shi, Venu Aruva, Paige Creeks, Joyce J. W. Wong, Jian Zhang, R. Stokes Peebles Jr., Derek Croote, Scott A. Smith, Geoffrey A. Mueller   +16 more
wiley   +1 more source

Protein Profile of Multiple Myeloma‐Derived Extracellular Vesicles for the Discovery of Novel Myeloma‐Related Biomarkers

Cancer Science, EarlyView.
Comparison of extracellular vesicles with parental cells through proteomic profiling, followed by an integrated bioinformatic pipeline including disease association and transcriptomic analyses, identifies candidate biomarkers for multiple myeloma. Among these, MIF emerges as a clinically relevant marker, supported by validation in patient samples and ...
Natalia Platonova, Gilda Aiello, Domenica Ronchetti, Valentina Citro, Rosanna Asselta, Lavinia Casati, Domenica Giannandrea, Elisa Taiana, Antonino Neri, Gloria Sini, Elisabetta Calzavara, Mauro Turrini, Alfonsina D'Amato, Raffaella Chiaramonte   +13 more
wiley   +1 more source

Method Matters: A Proteomics-Informed Framework for Selecting Extracellular Vesicle Isolation Methods for Plasma. [PDF]

J Extracell Biol
Werle SJ, Therkelsen MLN, Meng C, Grønborg M, Gluud LL, Damgaard D.   +5 more
europepmc   +1 more source

The Impact of Collection Protocol on the Yield and Purity of Mesenchymal Stem Cell-Derived Extracellular Vesicles Isolated From Serum-Free Media. [PDF]

Biotechnol J
Phelps J, Tamrin SH, Duncan NA, Sen A.
europepmc   +1 more source

Astrocytic connexin43 phosphorylation contributes to seizure susceptibility after mild traumatic brain injury

The FEBS Journal, EarlyView.
Astrocytic gap junctions formed by connexin43 (Cx43) help maintain brain homeostasis. After mild traumatic brain injury (TBI), total cortical Cx43 increases and redistributes toward a soluble, non‐junctional pool with elevated hemichannel activity and increased phosphorylation at serine 368 (pCx43S368).
Carmen Muñoz‐Ballester, Owen Leitzel, Samantha Golf, Chelsea M. Phillips, Michael J. Zeitz, Rahul Pandit, Elizabeth Wash, Jenna V. Donohue, Elizabeth A. Istre, James W. Smyth, Samy Lamouille, Stefanie Robel   +11 more
wiley   +1 more source

A Rapid Poly(ethylene glycol)-Assisted Magnetic Isolation Approach for High-Throughput Extracellular Vesicle Isolation and Subsequent Biomarker Analysis. [PDF]

ACS Nano
Sun L, Duke L, Vied C, Hammel G, Pate B, Wang J, Zhang Y, Tian DS, Fan J, Ren Y.   +9 more
europepmc   +1 more source

Contribution of endosomal proteins EHD1 and EHD4 to the HIV‐1 replication cycle

The FEBS Journal, EarlyView.
EHD1 and EHD4, two key trafficking proteins, regulate multiple stages of HIV‐1 infection: In producer cells, they help produce fully infectious virus particles, regulate Envelope protein incorporation in a cell‐type‐dependent manner, and limit the accumulation of antiviral IFITM proteins in virions.
Grégory Pacini, Konstantinos Poalas, Margaux Versapuech, Clarisse Berlioz‐Torrent, Katy Janvier   +4 more
wiley   +1 more source

Differential regulation of neutrophil degranulation by p38 MAPK and mitochondrial ROS during <i>Mycobacterium leprae</i> infection. [PDF]

Front Pharmacol
Tavares IF, Andrade RS, Cabral N, Pinheiro RO, Schmitz V.   +4 more
europepmc   +1 more source