Results 221 to 230 of about 117,742 (304)

Myocardial inflammation is associated with impaired mitochondrial oxidative capacity in ischaemic cardiomyopathy

ESC Heart Failure, Volume 12, Issue 2, Page 1246-1255, April 2025.
Abstract Aims Myocardial inflammation and impaired mitochondrial oxidative capacity are hallmarks of heart failure (HF) pathophysiology. The extent of myocardial inflammation in patients suffering from ischaemic cardiomyopathy (ICM) or dilated cardiomyopathy (DCM) and its association with mitochondrial energy metabolism are unknown.
Julius Borger, Elric Zweck, Constanze Moos, Patrick Horn, Fabian Voß, Heinz‐Peter Schultheiss, Jacob Eifer Møller, Udo Boeken, Hug Aubin, Artur Lichtenberg, Malte Kelm, Michael Roden, Amin Polzin, Ralf Westenfeld, Julia Szendroedi, Daniel Scheiber   +15 more
wiley   +1 more source

Targeting eEF1A1 With Baicalein to Block eEF1A1/Prdx4 Interaction for Treating Sepsis‐Mediated Lung Injury

Exploration, EarlyView.
Targeting eEF1A1 with baicalein disrupts the eEF1A1‐Prdx4 interaction to prevent RNF14‐mediated ubiquitination and degradation of Prdx4. This stabilizes Prdx4 to suppress NF‐κB, thereby alleviating sepsis‐induced acute lung injury. ABSTRACT Sepsis is a systemic inflammatory response syndrome triggered by an uncontrolled host response to infection ...
Jing Chang, Hui‐Lin Zhang, Qi‐Meng Zhu, Si‐Wen Hui, Xin‐Rong Xu, Mahmood Brobbey Oppong, Yan‐Li Feng, Juan Zhang, Cheng‐Peng Sun, Feng Qiu   +9 more
wiley   +1 more source

PDGFRA mediates the PI3K/AKT signaling pathway to regulate the growth and phenotype of GCTB tumor cells. [PDF]

Int J Clin Exp Pathol
Zhang T, Song W, Yan Z, Zhao Z, Chen Z, Tang F, Gao K, Chen F, Zhu H, Wang S.   +9 more
europepmc   +1 more source

1371 Tumoral CD68 expression associates with epithelial-to-mesenchymal transition and correlates with decreased CD68 T cell migration

Regular and Young Investigator Award Abstracts
Steve Arbitman, Jorge Blando, Radhika Rayanki, Lydia Greenlees, Tao Deng, Kleopatra Andreou, Vivian Ying Wang, Miranda Clements, Michael Surace, Paul Waring, Patricia McCoon, Luis Vence   +11 more
openaire   +1 more source

Water‐driven dispersible fiber electrode arrays for position‐dependent intracardiac electrophysiological recording

FlexMat, EarlyView.
Abstract Intracardiac electrophysiological recording plays an essential role in identifying abnormal cardiac electrical activity and guiding arrhythmia diagnosis and treatment planning. A key challenge for minimally invasive intracardiac electrodes is to combine reliable transvascular delivery with stable and compliant endocardial contact.
Jinyang Mao, Hangyu Li, Yuehui Yuan, Zixuan Chen, Shihan Xu, Ming Chu, Minglong Chen, Benhui Hu   +7 more
wiley   +1 more source

A Rare Case of Cutaneous Metastasis From Oral Squamous Cell Carcinoma (OSCC) and the Possible Role of GALR2 as a Biomarker: A Case Report. [PDF]

Clin Case Rep
Reis IB, de Carvalho MM, Ferrarezi DP, Fernandes NAR, Nascimento CR, Pelegrini ÁF, Rodrigues AMX, de Freitas Porsani A, Arbex FF, Junior CR.   +9 more
europepmc   +1 more source

Association of objectively assessed physical activity with immune cell infiltration of the tumor microenvironment in non-metastatic colon cancer. [PDF]

Int J Colorectal Dis
Renman D, Edin S, Gunnarsson U, Blind N, Strigård K, Palmqvist R.   +5 more
europepmc   +1 more source

Prolactin-Linked Plasma Cell-Macrophage Immune Phenotype in Synchronous Bilateral Plasma Cell Mastitis: A Two-Center Prediction Study with Tissue Correspondence. [PDF]

Int J Womens Health
Chen W, Li M, Feng J, Qu W, Zhang X, Li S, Sha S, Xue X, Jiang K, Wan H.   +9 more
europepmc   +1 more source

Research progress on the role of inflammatory mediators in the pathogenesis of epilepsy

Ibrain, Volume 11, Issue 1, Page 44-58, Spring 2025.
In the central nervous system, activated immune cells lead to the overproduction of inflammatory mediators through the corresponding signal pathway. Under the stimulation of inflammatory factors, neuroinflammation ultimately occurs. Overexpression of inflammatory mediators and activated immunocytes plays an important role in the emergence and ...
Yue Yu, Fei‐Ji Sun
wiley   +1 more source

Exploring the Role of Macrophage Marker CD68 in Pediatric Acute Myeloid Leukemia. [PDF]

Int J Mol Sci
Van Camp L, Vanhooren J, Depreter B, Hofmans M, D'Hont I, Chantrain C, Dedeken L, Van Damme A, Uyttebroeck A, Lammens T, De Moerloose B.   +10 more
europepmc   +1 more source