Results 221 to 230 of about 111,342 (306)

Metrnβ drives sepsis immunosuppression via macrophage reprogramming: A novel prognostic biomarker and therapeutic target

open access: yesInterdisciplinary Medicine, EarlyView.
Metrnβ serves as a novel prognostic biomarker for sepsis and that targeted blockade of the Metrnβ‐c‐Kit axis represents a promising therapeutic strategy for sepsis. Abstract Sepsis is a heterogeneous syndrome critically driven by immunosuppression, yet lacking personalized prognostic markers and therapeutic targets. Here, we provide evidence to support
Xiao Li   +15 more
wiley   +1 more source

Accumulation of Siglec10<sup>+</sup>CX3CR1<sup>+</sup> Macrophages in the Tumor Microenvironment of Glioblastomas. [PDF]

open access: yesEur J Immunol
Andreas N   +8 more
europepmc   +1 more source

Single‐Cell Profiling Identifies CLEC5A+ Macrophages as Key Drivers of Thoracic Aortic Aneurysm Via CCL5‐Mediated M1 Polarization

open access: yesJournal of Clinical Laboratory Analysis, EarlyView.
Thoracic aortic aneurysm (TAA) is a life‐threatening cardiovascular disease with limited therapeutic options. Through single‐cell RNA sequencing of aortic tissues from healthy individuals and TAA patients (105,541 cells), we identified CLEC5A+macrophages as the predominant pathogenic cell population exhibiting the highest M1 polarization score. Machine
Xiangyu Li   +3 more
wiley   +1 more source

Tumor-Associated Macrophage Infiltration and PD-L1 Expression in Gastric Cancer According to a Modified TCGA-Based Classification. [PDF]

open access: yesJ Gastric Cancer
Song B   +11 more
europepmc   +1 more source

Systematic Review and Meta‐Analysis of Resection Sequence in Synchronous Colorectal Liver Metastasis: Primary vs. Liver First

open access: yesJournal of Surgical Oncology, EarlyView.
ABSTRACT Background This present systematic review and meta‐analysis aims to compare overall survival (OS), disease‐free survival (DFS), morbidity and mortality outcomes in patients undergoing colorectal first (CRf) versus liver first (Lf) resections with synchronous colorectal liver metastases.
Sofoklis Mavrantonis   +3 more
wiley   +1 more source

Macrophages, TGF-β1 expression and iron deposition in development of NASH

open access: yesOpen Medicine, 2012
Ananiev Julian   +3 more
doaj   +1 more source

Post‐Radiation Granuloma Annulare: A Series of Three Cases

open access: yesJEADV Clinical Practice, EarlyView.
ABSTRACT We report typical cases of biopsy confirmed granuloma annulare occurring on irradiated skin in the context of breast cancer in three women in their seventies. The lesions appeared immediately after start of irradiation in one patient, 4 and 15 months after the end of radiation treatment in the other two. The lesions eventually spread elsewhere
Léa Scheid, Mona Mitcov, Dan Lipsker
wiley   +1 more source

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