Results 1 to 10 of about 49,899 (288)

Effect of Maternal CD163 Knockout on PRRSV Replication and Vertical Transmission. [PDF]

Animals (Basel)
Porcine reproductive and respiratory syndrome virus (PRRSV) depends on the CD163 receptor to establish infection. Although CD163-knockout (KO) pigs exhibit resistance to PRRSV-related respiratory disease, their reproductive performance following viral ...
Han F, Wang C, Liang G, Luo X, Zhang J, Wu Z, Yang H.   +6 more
europepmc   +2 more sources

Molecular and Clinical Characterization of CD163 Expression via Large-Scale Analysis in Glioma

OncoImmunology, 2019
The expression and function of CD163 in glioma are not fully understood. In this report, we collected totally 1323 glioma samples from the Chinese Glioma Genome Atlas (CGGA) dataset, including 325 RNA-seq data and 301 mRNA microarray data, and 697 glioma
Zhen Zhang, Lan Huang, Nomathamsanqa Resegofetse Maimela   +2 more
exaly   +2 more sources

CD163ΔSRCR5 MARC-145 Cells Resist PRRSV-2 Infection via Inhibiting Virus Uncoating, Which Requires the Interaction of CD163 With Calpain 1

Frontiers in Microbiology, 2020
Porcine alveolar macrophages without the CD163 SRCR5 domain are resistant to porcine reproductive and respiratory syndrome virus (PRRSV) infection. However, whether the deletion of CD163 SRCR5 in MARC-145 cells confers resistance to PRRSV and interaction
Xiaohong Liu, Yaosheng Chen, Chunhe Guo
exaly   +3 more sources

Highly Efficient Generation of Pigs Harboring a Partial Deletion of the CD163 SRCR5 Domain, Which Are Fully Resistant to Porcine Reproductive and Respiratory Syndrome Virus 2 Infection

Frontiers in Immunology, 2019
Porcine reproductive and respiratory syndrome virus (PRRSV) 1 and 2 differ in their recognition of CD163. Substitution of porcine CD163 SRCR5 domain with a human CD163-like SRCR8 confers resistance to PRRSV 1 but not PRRSV 2.
Xiaohong Liu, Yongchang Cao, Yaosheng Chen   +2 more
exaly   +3 more sources

Reduced Membrane CD163 Expression in 7-Oxysterol-Induced Apoptosis Accompanied by Elevated Oxidative Stress. [PDF]

Cells
CD163 is a transmembrane scavenger receptor predominantly expressed by activated M2-like macrophages and is involved in inflammatory processes. Oxysterols, which accumulate in atherosclerotic lesions, are known to induce oxidative stress and apoptosis in
Li W, Yuan XM.
europepmc   +2 more sources

Impact of Cox2, CD163, and Microvessel Density Expression on the Prediction of Relapse and Patients’ Outcome in Classical Hodgkin Lymphoma [PDF]

Middle East Journal of Cancer, 2022
Background: Tumor microenvironment, specifically tumor-associated macrophages, plays an important role in tumor initiation and progression. CD163 has been recognized as a valuable specific macrophage marker.
Rania Makboul, Abeer Refaiy, Rabab Mohamed, Alia Attia, Dalia Osama, Amany El Emary, Abeer Ibrahim   +6 more
doaj   +1 more source

Immunohistochemical expression of CD163 in colorectal carcinoma and its prognostic value

Journal of the Arab Society for Medical Research, 2023
Background/aim Colorectal cancer (CRC) is one of the most frequent cancers worldwide with one of the highest mortality rate. CD163 is a 130-KDa transmembrane protein, known to be involved in hemoglobin clearance by functioning as a receptor for ...
Noha N Yassen, Marwa E Shabana, Maha K Desouky, Manal A Badawi, Dalia M Abouelfadl   +4 more
doaj   +1 more source

Expression of scavenger receptors CD163, CD204, and CD206 on macrophages in patients with pulmonary tuberculosis

Бюллетень сибирской медицины, 2023
The aim of the study was to evaluate the expression of scavenger receptors (CD163, CD204, CD206) on macrophages in patients with pulmonary tuberculosis, depending on the clinical form of the disease and sensitivity of the pathogen to anti-tuberculosis ...
E. G. Churina, A. V. Popova, O. I. Urazova, M. R. Patysheva, Ju. V. Kolobovnikova, S. P. Chumakova   +5 more
doaj   +1 more source

CD163⁺ macrophages coordinate erythroblastic Island formation and iron metabolism to enable glucocorticoid-induced erythropoiesis. [PDF]

Biomark Res
Background Glucocorticoids(GCs) are widely used to treat erythropoietin-resistant anemias, yet the precise mechanisms underlying their erythropoiesis-promoting effects remain incompletely understood.
Li M, Wang Y, Huang H, Sun H, Gao M, Sun M, Li X, Liu Z, Liu D, Yan M, Huang Z, Zhang Z, Hu Y, Wang B, Zhou Y, Li S, An Y, Liu M, Liu Y, Gao F, Ge F, Fan W, Wang H, Li X, Wang F, Fu G, Zuo S, Zhang B, Miao J, Wang C, Song Y, An X, Cao W, Xu L, Li W, Bian Z.   +35 more
europepmc   +2 more sources

Relationship of Tumor-Associated Macrophage Population Detected by CD68 PG-M1, CD68 KP1, and CD163 with Latent EBV Infection and Prognosis in Classical Hodgkin Lymphoma

Türk Patoloji Dergisi, 2021
Objective: To evaluate the quantity of tumor-associated macrophages (TAMs) in cases of Hodgkin Lymphoma of classical type (cHL), and to reveal possible associations between TAM intensity and latent Epstein-Barr virus (EBV) infection, overall survival ...
Hanife Seda MAVILI, Aydın ISISAG, Ayca TAN, Mine MISKIOGLU, Lale SAKA BARAZ, Nalan NESE   +5 more
doaj   +1 more source