Results 1 to 10 of about 49,329 (202)
International Journal of Molecular Sciences, 2022 Hyperglycemia, a hallmark of diabetes, can induce inflammatory programming of macrophages. The macrophage scavenger receptor CD163 internalizes and degrades hemoglobin-haptoglobin (Hb-Hp) complexes built due to intravascular hemolysis.
L. Matuschik +6 more
semanticscholar +1 more source
Cancer Letters, 2021 Colorectal cancer (CRC) accounts for about 10% of cancer deaths worldwide. Colon carcinogenesis is critically influenced by the tumor microenvironment.
M. Stadler +14 more
semanticscholar +1 more source
Brain, behavior, and immunity, 2022 Alpha-synuclein pathology is associated with immune activation and neurodegeneration in Parkinson's disease. The immune activation involves not only microglia but also peripheral immune cells, such as mononuclear phagocytes found in blood and infiltrated
Sara Konstantin Nissen +6 more
semanticscholar +1 more source
Journal of Integrative Agriculture, 2023 Porcine reproductive and respiratory syndrome (PRRS) is recognized as one of the most infectious viral diseases of swine. Although Cluster of differentiation 163 (CD163) is identified as an essential receptor for mediating PRRS virus (PRRSV) infection ...
Kui XU +9 more
doaj +1 more source
Annals of Translational Medicine, 2022 Background Studies have found that tumor-associated macrophages (TAMs) in the malignant ascites of patients with serous ovarian cancer exhibit a mixed polarization phenotype and highly variable expression of the surface marker CD163.
Xiaohui Zhang +6 more
semanticscholar +1 more source
Cancer Medicine, 2023 Background Progestins are used as fertility‐sparing regimens for young patients with stage 1A endometrioid endometrial cancer (EEC) and atypical endometrial hyperplasia (AEH).
Lulu Wang +6 more
doaj +1 more source
The TWEAK/Fn14/CD163 axis—implications for metabolic disease
Reviews in Endocrine & Metabolic Disorders, 2021 TWEAK (tumor necrosis factor-like weak inducer of apoptosis) is a member of the TNF superfamily that controls a multitude of cellular events including proliferation, migration, differentiation, apoptosis, angiogenesis, and inflammation.
W. Ratajczak, S. D. Atkinson, C. Kelly
semanticscholar +1 more source
Differential expression of CD163 on monocyte subsets in healthy and HIV-1 infected individuals. [PDF]
PLoS ONE, 2011 CD163, a haptoglobin-hemoglobin (Hp-Hb) scavenger receptor, expressed by monocytes and macrophages, is important in resolution of inflammation. Age-related non-AIDS co-morbidities in HIV-infected individuals, particularly dementia and cardiovascular ...
Emma Tippett +7 more
doaj +1 more source
Dysregulation of the CD163-Haptoglobin Axis in the Airways of COPD Patients
Cells, 2021 Pulmonary iron levels are increased in chronic obstructive pulmonary disease (COPD) patients. Iron causes oxidative stress and is a nutrient for pathogenic bacteria. Iron may therefore play an important role in the pathophysiology of COPD.
Andrew Higham +5 more
doaj +1 more source
Current Issues in Molecular Biology, 2022 This study aimed to compare tissue levels of CD80 (pro-inflammatory macrophage-related surface marker), CD163, and CD206 (anti-inflammatory macrophage-related surface markers), and their ratios in periodontal and peri-implant health and disease ...
Mustafa Yilmaz +4 more
doaj +1 more source