Results 21 to 30 of about 48,020 (257)

The Ratio of CD86+/CD163+ Macrophages Predicts Postoperative Recurrence in Stage II-III Colorectal Cancer

Frontiers in Immunology, 2021
Tumor-associated macrophages (TAMs) are pivotal for tumor progression and metastasis. We investigated the stromal CD86+TAM/CD163+TAM (CD86/CD163) ratio as a novel prognostic biomarker for stage II-III colorectal cancer (CRC).
Guozeng Xu, Lei Jiang, Cheng Ye, Guizhen Qin, Zhanxiong Luo, Yuzhen Mo, Jian Chen   +6 more
doaj   +1 more source

Macrophage Densities Correlated with CXC Chemokine Receptor 4 Expression and Related with Poor Survival in Anaplastic Thyroid Cancer [PDF]

Endocrinology and Metabolism, 2016
BackgroundTumor associated macrophages (TAMs) and CXC chemokine receptor 4 (CXCR4) have emerged as potential biomarkers in various human cancers. The aims of this study were to investigate the clinical characteristics of anaplastic thyroid cancer (ATC ...
Dae In Kim, Eunyoung Kim, Young A Kim, Sun Wook Cho, Jung Ah Lim, Young Joo Park   +5 more
doaj   +1 more source

CD163 and its role in inflammation [PDF]

, 2011
Mononuclear phagocytes represent a heterogeneous population of cells with individual subpopulations exerting different pro- or anti-inflammatory functions.
Lech Chyczewski, Kowal, Krzysztof, Emila Sławińska, Sławińska, Emila, Kowal-Bielecka, Otylia, Otylia Kowal-Bielecka, Chyczewski, Lech, Richard Silver, Krzysztof Kowal, Silver, Richard, Bielecki, Marek, Marek Bielecki   +11 more
core   +1 more source

Mouse CD163 deficiency strongly enhances experimental collagen-induced arthritis [PDF]

, 2020
The scavenger receptor CD163 is highly expressed in macrophages in sites of chronic inflammation where it has a not yet defined role. Here we have investigated development of collagen-induced arthritis (CIA) and collagen antibody-induced arthritis (CAIA)
Søren K. Moestrup, Etzerodt, Anders, Moestrup, Søren K., Pia Svendsen, Deleuran, Bent W., Anders Etzerodt, Bent W. Deleuran, Svendsen, Pia   +7 more
core   +1 more source

RNA‐seq and ATAC‐seq analysis of CD163+ macrophage‐induced progestin‐insensitive endometrial cancer cells

Cancer Medicine, 2023
Background Progestins are used as fertility‐sparing regimens for young patients with stage 1A endometrioid endometrial cancer (EEC) and atypical endometrial hyperplasia (AEH).
Lulu Wang, Qiaoying Lv, Pengfei Wu, Shuhan Luo, Sijia Liu, Xiaojun Chen, Xuezhen Luo   +6 more
doaj   +1 more source

Pig macrophages with site-specific edited CD163 decrease the susceptibility to infection with porcine reproductive and respiratory syndrome virus

Journal of Integrative Agriculture, 2023
Porcine reproductive and respiratory syndrome (PRRS) is recognized as one of the most infectious viral diseases of swine. Although Cluster of differentiation 163 (CD163) is identified as an essential receptor for mediating PRRS virus (PRRSV) infection ...
Kui XU, Yan-rong ZHOU, Hai-tao SHANG, Chang-jiang XU, Ran TAO, Wan-jun HAO, Sha-sha LIU, Yu-lian MU, Shao-bo XIAO, Kui LI   +9 more
doaj   +1 more source

Differential expression of CD163 on monocyte subsets in healthy and HIV-1 infected individuals. [PDF]

PLoS ONE, 2011
CD163, a haptoglobin-hemoglobin (Hp-Hb) scavenger receptor, expressed by monocytes and macrophages, is important in resolution of inflammation. Age-related non-AIDS co-morbidities in HIV-infected individuals, particularly dementia and cardiovascular ...
Emma Tippett, Wan-Jung Cheng, Clare Westhorpe, Paul U Cameron, Bruce J Brew, Sharon R Lewin, Anthony Jaworowski, Suzanne M Crowe   +7 more
doaj   +1 more source

Prognostic Implications of Tumor-Associated Macrophages in Oral Squamous Cell Carcinoma: A Systematic Review and Meta-Analysis

Journal of Orofacial Sciences
Introduction: Tumor-associated macrophages (TAMs) are the major cellular component in the tumor microenvironment of oral squamous cell carcinoma (OSCC). Several studies have been put forward to assess the role of TAMs in the prognostication of OSCC.
Surya Surendran L, Anna Palliath Joseph, Varun B Raghavan Pillai, Vinej Somaraj, Sunjith Sudhakar, Amitha Mohan   +5 more
doaj   +1 more source

Dysregulation of the CD163-Haptoglobin Axis in the Airways of COPD Patients

Cells, 2021
Pulmonary iron levels are increased in chronic obstructive pulmonary disease (COPD) patients. Iron causes oxidative stress and is a nutrient for pathogenic bacteria. Iron may therefore play an important role in the pathophysiology of COPD.
Andrew Higham, James M. Baker, Natalie Jackson, Rajesh Shah, Simon Lea, Dave Singh   +5 more
doaj   +1 more source

Tissue Levels of CD80, CD163 and CD206 and Their Ratios in Periodontal and Peri-Implant Health and Disease

Current Issues in Molecular Biology, 2022
This study aimed to compare tissue levels of CD80 (pro-inflammatory macrophage-related surface marker), CD163, and CD206 (anti-inflammatory macrophage-related surface markers), and their ratios in periodontal and peri-implant health and disease ...
Mustafa Yilmaz, Esra Demir, Yigit Firatli, Erhan Firatli, Ulvi Kahraman Gürsoy   +4 more
doaj   +1 more source