Results 11 to 20 of about 48,020 (257)

Preferential use of Siglec-1 or Siglec-10 by type 1 and type 2 PRRSV strains to infect PK15S1–CD163 and PK15S10–CD163 cells [PDF]

Veterinary Research, 2018
Cellular entry mediators define whether the cell is permissive to PRRSV infection. Porcine sialoadhesin (pSn, Siglec-1) and CD163 are main entry mediators facilitating infection of porcine macrophages by PRRSV.
Jiexiong Xie, Isaura Christiaens, Bo Yang, Ivan Trus, Bert Devriendt, Tingting Cui, Ruifang Wei, Hans J. Nauwynck   +7 more
doaj   +2 more sources

CD163 at the crossroads: a viral-exploited immunomodulator

Virology Journal
Porcine reproductive and respiratory syndrome virus (PRRSV) is a major pathogen in pigs and poses a significant economic threat to the pig industry. CD163 acts as a key cellular receptor for PRRSV infection, mediating viral entry into host cells.
Jiayong Tan, Jie Cheng, Xiaohui Yang, Jian Zhang, Huaqiang Yang   +4 more
doaj   +2 more sources

CD163: a potential biomarker for lupus nephritis activity. [PDF]

Lupus Sci Med
Objectives CD163 is a macrophage-associated scavenger receptor shed during inflammatory activation, resulting in measurable soluble CD163 in serum (s) and urine (u).
Gürel E, Çinar S, Hürdogan Ö, Özlük Y, Kemeç G, Uludağ Ö, Varelci S, Mirioğlu S, Yalçinkaya Y, Gül A, Inanç M, Artim-Esen B.   +11 more
europepmc   +2 more sources

Peripheral blood CD163(+) monocytes and soluble CD163 in dry and neovascular age-related macular degeneration [PDF]

, 2020
Macrophages are the main infiltrating immune cells in choroidal neovascularization (CNV), a hallmark of the human wet, or neovascular age-related macular degeneration (AMD).
Hasanpour, Hossein, Garweg, Justus G., Zandi, Souska, Barakat, Aliaa, Pirmardan, Ehsan Ranaei, Piryaie, Golbarg, Ahmadieh, Hamid, Nejad, Qurban Behzadian, Pfister, Isabel B., Zarif, Mahin Nikougoftar, Nakao, Shintaro, Daftarian, Narsis, Samiei, Shahram, Soheili, Zahra‐Soheila, Yamaguchi, Muneo, Hafezi‐Moghadam, Ali   +15 more
core   +1 more source

Elevated soluble CD163 in gestational diabetes mellitus : secretion from human placenta and adipose tissue [PDF]

, 2014
Recently soluble CD163 (sCD163), a cleaved form of the macrophage receptor CD163, was identified as a macrophage-specific risk-predictor for developing Type 2 Diabetes.
Bastie, Claire C., Tan, Bee Kang, Bari, Muhammad F., Tan, BK, Bari, MF, Snead, DR, Harpal Singh Randeva, James, SG, Sivakumar, K, Bastie, CC, Weickert, MO, Martin O Weickert, Snead, David R., Vatish, Manu, James, Sean G., Manu Vatish, Sean G James, Randeva, Harpal Singh, Sivakumar, Kavitha, Weickert, Martin O., Randeva, HS, Snead, David R. J., Tan, Bee K., David R J Snead, Randeva, Harpal S., Muhammad Furqan Bari, Bastie, Claire Cecile, Claire Cecile Bastie, Vatish, M, Kavitha Sivakumar, Bee Kang Tan   +30 more
core   +2 more sources

Immuno-phenotyping of IDH-mutant grade 3 astrocytoma and IDH-wildtype glioblastoma reveals specific differences in cells of myeloid origin

OncoImmunology, 2021
Gliomas are heavily infiltrated with immune cells of myeloid origin. Past studies have shown that high-grade gliomas have a higher proportion of alternatively activated and suppressive myeloid cells when compared to low-grade gliomas, which correlate ...
Jayashree V. Raghavan, Raksha A. Ganesh, Pranali Sonpatki, Divya Naik, Arivusudar Everad John, Priyanka Arunachalam, Darshat Shah, Hari P. S., Akhila Lakshmikantha, Shibu Pillai, Komal Prasad Chandrachari, Kiran Mariswamappa, Sathyanarayana Lale, Nameeta Shah, Siddharth Jhunjhunwala   +14 more
doaj   +1 more source

Soluble ectodomain CD163 and extracellular vesicle-associated CD163 are two differently regulated forms of `soluble CD163' in plasma [PDF]

, 2017
International audienceCD163 is the macrophage receptor for uptake of hemoglobin-haptoglobin complexes. The human receptor can be shed from the macrophage surface owing to a cleavage site for the inflammationinducible TACE/ADAM17 enzyme.
Andersen, Morten N., Bebien, Magali, Bebien, M., Berg, Ronan M.G., Møller, H. J., Moestrup, Soren K., Berg, Ronan M. G., Plovsing, R. R., Habbeddine, M., Habbeddine, Mohamed, Andersen, M. N., Etzerodt, Anders, Berg, R. M., Lawrence, Toby, Møller, Holger J., Moestrup, Søren K., Moestrup, S. K., Plovsing, Ronni R., Moller, Holger J., Etzerodt, A.   +19 more
core   +1 more source

Recognition mechanisms of hemoglobin particles by monocytes – CD163 may just be one

Beilstein Journal of Nanotechnology, 2023
Hemoglobin-based oxygen carriers (HBOCs) as blood substitutes are one of the great hopes of modern transfusion and emergency medicine. After the major safety-relevant challenges of the last decades seem to be largely overcome, current developments have ...
Jonathan-Gabriel Nimz, Pichayut Rerkshanandana, Chiraphat Kloypan, Ulrich Kalus, Saranya Chaiwaree, Axel Pruß, Radostina Georgieva, Yu Xiong, Hans Bäumler   +8 more
doaj   +1 more source

CD163 expression in leukemia cutis [PDF]

, 2010
Background: Proper diagnosis of myeloid leukemia cutis (LC) is of great clinical importance but can be difficult because no single immunohistochemical marker is adequately sensitive or specific for definitive diagnosis.
Bandarchi, Bizhan, Ma, Linglei, Harms, Paul W.   +2 more
core   +1 more source

KARAKTERISTIK EKSPRESI CD163 PADA TUMOR GANAS OVARIUM [PDF]

, 2023
Immune checkpoint blcokade therapy yang menjadi kandidat terapi kanker menjanjikan, menunjukkan rata-rata respon yang rendah pada kanker ovarium. Hal ini disebakan karena heterogenesitas lingkungan mikronya.
Rasyid, Riana Sari Puspita, Wresnindyatsih, Wresnindyatsih, Antania Phelia Zen, Raissa Nurwany, Wresnindyatsih Wresnindyatsih, Soilia Fertilita, Nurwany, Raissa, Larasaty, Shafa, Zen, Antania Phelia, Fertilita, Soilia, Riana Sari Puspita Rasyid, Shafa Larasaty   +11 more
core   +3 more sources