Streptococcus pneumoniae serotype 1 capsular polysaccharide induces CD8CD28 regulatory T lymphocytes by TCR crosslinking. [PDF]
Zwitterionic capsular polysaccharides (ZPS) of commensal bacteria are characterized by having both positive and negative charged substituents on each repeating unit of a highly repetitive structure that has an alpha-helix configuration.
Janina Mertens+14 more
doaj +5 more sources
Age-related decrease of miRNA-92a levels in human CD8+ T-cells correlates with a reduction of naïve T lymphocytes [PDF]
MicroRNA (miR)-17-92a expression plays a crucial role in lymphocyte ontogeny. We therefore set out to determine miR-92a expression levels in peripheral blood lymphocytes from healthy subjects to ascertain any association between these levels and ageing ...
Ohyashiki Michiyo+4 more
doaj +5 more sources
Trans-active factors controlling the IL-2 gene in adult human T-cell subsets [PDF]
IL-2 secretion in total or subsets of PHA/PMA-stimulated PBMC-derived human T-lymphocytes was monitored and found to be largely due to CD4+CD8− cells. The presence and functional state of transcription factors (TF) was assessed by protein-DNA interaction
A. Mouzaki+3 more
doaj +4 more sources
Upregulation of FOXP3+Regulatory T Lymphocytes and CD8+Lymphocytes in Patients with High-Grade Squamous Intraepithelial Lesions Correlated with HPV Infection [PDF]
Raksts ir publicēts 2022.gada aprīlī. Tas redzams žurnāla publikācijā, raksta PDF publikācijā un Web of Science publikācijā. Scopus datubāzē publicēšanas gads ir norādīts kļūdaini kā 2021.gads.
Gordjušina, Valentina+4 more
core +1 more source
Ly49E Expression on CD8αα-expressing intestinal intraepithelial lymphocytes plays no detectable role in the development and progression of experimentally induced inflammatory bowel diseases [PDF]
The Ly49E NK receptor is a unique inhibitory receptor, presenting with a high degree of conservation among mouse strains and expression on both NK cells and intraepithelial-localised T cells.
Devisscher, Lindsey+11 more
core +13 more sources
Prolonged enhancement of cytotoxic T lymphocytes in the post-recovery state of severe COVID-19
We evaluated the peripheral blood immune responses of lymphocytes in severe Coronavirus disease 2019 (COVID-19) patients in different stages of recovery using single-cell mass cytometry.
Yumi Mitsuyama+5 more
doaj +1 more source
Erythrodermic CD4/CD8 Double-Negative Mycosis Fungoides: A Case Report
Cutaneous T-cell lymphoma (CTCL) describes a group of lymphoproliferative disorders characterized by localization of neoplastic T lymphocytes to the skin. Mycosis fungoides (MF) represents the most common type of CTCL and accounts for ∼60% of all primary
Monira Abdullah Alnasser+4 more
doaj +1 more source
Causes of T lymphocyte activation in HIV-infected patients coinfected with hepatitis C virus [PDF]
Aim. To establish the causes of T lymphocyte activation in human immunodeficiency virus (HIV)-infected patients coinfected with hepatitis C (HCV) who are adherent to their antiretroviral therapy regimen and interferon untreated.
K V Shmagel+4 more
doaj +1 more source
A murine intestinal intraepithelial NKp46-negative innate lymphoid cell population characterized by group 1 properties [PDF]
The Ly49E receptor is preferentially expressed on murine innate-like lymphocytes, such as epidermal V gamma 3 T cells, intestinal intraepithelial CD8 alpha alpha(+) T lymphocytes, and CD49a(+) liver natural killer (NK) cells.
Biswas, Aindrila+15 more
core +2 more sources
Negative and positive selection of antigen-specific cytotoxic T lymphocytes affected by the α3 domain of MHC I molecules [PDF]
THE α1 and α2 domains of major histocompatibility complex (MHC) class I molecules function in the binding and presentation of foreign peptides to the T-cell antigen receptor and control both negative and positive selection of the T-cell repertoire ...
AM Norment+30 more
core +1 more source