Results 21 to 30 of about 289,022 (294)

Effector functions of CD8-positive guinea pig T lymphocytes

open access: yesCellular Immunology, 2003
The response of guinea pig T lymphocytes to different stimuli was analysed with focus on the functions of CD8-positive T cells, which so far had been poorly defined in this animal model. For identification and purification of guinea pig cytotoxic T lymphocytes, three monoclonal antibodies, directed against the CD8 differentiation antigen were ...
Schafer, H   +4 more
openaire   +3 more sources

A Study on Tumor-Infiltrating Lymphocytes in Different Subtypes of Breast Cancer [PDF]

open access: yesJournal of Biomedical & Clinical Research, 2021
The study aimed to investigate immune cell infiltration in different subtypes of breast cancer (BC). Retrospectively were selected 100 patients with primary BC, grouped into four molecular surrogate subtypes (Luminal A and Luminal B-like, HER2-positive ...
Polina Dimitrova   +2 more
doaj   +3 more sources

Spinal Cord T-Cell Infiltration in the Rat Spared Nerve Injury Model: A Time Course Study. [PDF]

open access: yes, 2016
The immune system is involved in the development of neuropathic pain. In particular, the infiltration of T-lymphocytes into the spinal cord following peripheral nerve injury has been described as a contributor to sensory hypersensitivity.
Clarke, C.B.   +7 more
core   +2 more sources

Glutamine or whey-protein supplementation on alloxan-induced diabetic rats. Effects on CD4+ and CD8+ lymphocytes Efeitos da oferta de glutamina ou de proteína do soro de leite sobre os linfócitos CD4+ e CD8+ em ratos diabéticos aloxano induzidos

open access: yesActa Cirúrgica Brasileira, 2007
PURPOSE: To evaluate the effects of glutamine (L-Gln) or whey-protein supplementation on CD4+ and CD8+ lymphocytes in alloxan-induced diabetic rats. METHODS: Thirty-two healthy male Wistar rats were used in the experiment.
Renato Motta Neto   +5 more
doaj   +1 more source

Streptococcus pneumoniae serotype 1 capsular polysaccharide induces CD8CD28 regulatory T lymphocytes by TCR crosslinking. [PDF]

open access: yesPLoS Pathogens, 2009
Zwitterionic capsular polysaccharides (ZPS) of commensal bacteria are characterized by having both positive and negative charged substituents on each repeating unit of a highly repetitive structure that has an alpha-helix configuration.
Janina Mertens   +14 more
doaj   +1 more source

Enhanced CXCR4 Expression of Human CD8Low T Lymphocytes Is Driven by S1P4

open access: yesFrontiers in Immunology, 2021
Although the human immune response to cancer is naturally potent, it can be severely disrupted as a result of an immunosuppressive tumor microenvironment.
Tobias Burkard   +6 more
doaj   +1 more source

IL-27 shapes the immune properties of human astrocytes and their impact on encountered human T lymphocytes

open access: yesJournal of Neuroinflammation, 2022
Background Interleukin-27 (IL-27) can trigger both pro- and anti-inflammatory responses. This cytokine is elevated in the central nervous system (CNS) of multiple sclerosis (MS) patients, but how it influences neuroinflammatory processes remains unclear.
Florent Lemaître   +13 more
doaj   +1 more source

Mice Deficient in Nucleoporin Nup210 Develop Peripheral T Cell Alterations

open access: yesFrontiers in Immunology, 2018
The nucleopore is an essential structure of the eukaryotic cell, regulating passage between the nucleus and cytoplasm. While individual functions of core nucleopore proteins have been identified, the role of other components, such as Nup210, are poorly ...
Annemarie van Nieuwenhuijze   +19 more
doaj   +1 more source

Overexpression of PD-1 and CD39 in tumor-infiltrating lymphocytes compared with peripheral blood lymphocytes in triple-negative breast cancer.

open access: yesPLoS ONE, 2022
Background and aimGrowing evidence highlighted the primary role of the immune system in the disease course of triple-negative breast cancer (TNBC). The study aim was to investigate the expression of PD-1 and CD39 on CD4+ and CD8+ cells infiltrating tumor
Asmaa M Zahran   +6 more
doaj   +1 more source

Comparison of T and NK lymphocyte subsets between human endometrial tissue and peripheral blood

open access: yesCentral European Journal of Immunology, 2019
Immune profiles in endometrium may be changed in patients with IVF failure and its possible correlations with immune parameters in peripheral blood are important for the diagnostic approach.
Viktor Chernyshov   +3 more
doaj   +1 more source

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