Acta Cirúrgica Brasileira, 2007 PURPOSE: To evaluate the effects of glutamine (L-Gln) or whey-protein supplementation on CD4+ and CD8+ lymphocytes in alloxan-induced diabetic rats. METHODS: Thirty-two healthy male Wistar rats were used in the experiment.
Renato Motta Neto +5 more
doaj +1 more source
Streptococcus pneumoniae serotype 1 capsular polysaccharide induces CD8CD28 regulatory T lymphocytes by TCR crosslinking. [PDF]
PLoS Pathogens, 2009 Zwitterionic capsular polysaccharides (ZPS) of commensal bacteria are characterized by having both positive and negative charged substituents on each repeating unit of a highly repetitive structure that has an alpha-helix configuration.
Janina Mertens +14 more
doaj +1 more source
Mice Deficient in Nucleoporin Nup210 Develop Peripheral T Cell Alterations
Frontiers in Immunology, 2018 The nucleopore is an essential structure of the eukaryotic cell, regulating passage between the nucleus and cytoplasm. While individual functions of core nucleopore proteins have been identified, the role of other components, such as Nup210, are poorly ...
Annemarie van Nieuwenhuijze +19 more
doaj +1 more source
Journal of Neuroinflammation, 2022 Background Interleukin-27 (IL-27) can trigger both pro- and anti-inflammatory responses. This cytokine is elevated in the central nervous system (CNS) of multiple sclerosis (MS) patients, but how it influences neuroinflammatory processes remains unclear.
Florent Lemaître +13 more
doaj +1 more source
The frequency of Chlamydia trachomatis major outer membrane protein-specific CD8+ T lymphocytes in active trachoma is associated with current ocular infection. [PDF]
, 2006 Chlamydia-specific cytotoxic T lymphocytes are able to control model infections but may be implicated in disease pathogenesis. HLA-A2 peptide tetramers to Chlamydia trachomatis major outer membrane protein 258-266 (MOMP258-266) and MOMP260-268 were used ...
Nkoyo Faal +19 more
core +1 more source
PLoS ONE, 2022 Background and aimGrowing evidence highlighted the primary role of the immune system in the disease course of triple-negative breast cancer (TNBC). The study aim was to investigate the expression of PD-1 and CD39 on CD4+ and CD8+ cells infiltrating tumor
Asmaa M Zahran +6 more
doaj +1 more source
Enhanced CXCR4 Expression of Human CD8Low T Lymphocytes Is Driven by S1P4
Frontiers in Immunology, 2021 Although the human immune response to cancer is naturally potent, it can be severely disrupted as a result of an immunosuppressive tumor microenvironment.
Tobias Burkard +6 more
doaj +1 more source
Comparison of T and NK lymphocyte subsets between human endometrial tissue and peripheral blood
Central European Journal of Immunology, 2019 Immune profiles in endometrium may be changed in patients with IVF failure and its possible correlations with immune parameters in peripheral blood are important for the diagnostic approach.
Viktor Chernyshov +3 more
doaj +1 more source
Activated CD8+ T lymphocytes inhibit neural stem/progenitor cell proliferation: role of interferon-gamma. [PDF]
PLoS ONE, 2014 The ability of neural stem/progenitor cells (NSCs) to self-renew, migrate to damaged sites, and differentiate into neurons has renewed interest in using them in therapies for neurodegenerative disorders.
Shuxian Hu +3 more
doaj +1 more source
De Novo generation of escape Variant-specific CD8+ T-Cell responses following Cytotoxic T-Lymphocyte escape in chronic Human Immunodeficiency Virus Type 1 Infection [PDF]
, 2005 Human immunodeficiency virus type 1 (HIV-1) evades CD8+ T-cell responses through mutations within targeted epitopes, but little is known regarding its ability to generate de novo CD8+ T-cell responses to such mutants.
Allgaier, R.L. +35 more
core +1 more source