Results 21 to 30 of about 15,870,834 (185)

Causes of T lymphocyte activation in HIV-infected patients coinfected with hepatitis C virus [PDF]

Терапевтический архив, 2016
Aim. To establish the causes of T lymphocyte activation in human immunodeficiency virus (HIV)-infected patients coinfected with hepatitis C (HCV) who are adherent to their antiretroviral therapy regimen and interferon untreated.
K V Shmagel, N G Shmagel, L B Korolevskaya, E V Saydakova, V A Chereshnev   +4 more
doaj   +1 more source

A Study on Tumor-Infiltrating Lymphocytes in Different Subtypes of Breast Cancer [PDF]

Journal of Biomedical & Clinical Research, 2021
The study aimed to investigate immune cell infiltration in different subtypes of breast cancer (BC). Retrospectively were selected 100 patients with primary BC, grouped into four molecular surrogate subtypes (Luminal A and Luminal B-like, HER2-positive ...
Polina Dimitrova, Savelina Popovska, Ivan Ivanov   +2 more
doaj   +3 more sources

Glutamine or whey-protein supplementation on alloxan-induced diabetic rats. Effects on CD4+ and CD8+ lymphocytes Efeitos da oferta de glutamina ou de proteína do soro de leite sobre os linfócitos CD4+ e CD8+ em ratos diabéticos aloxano induzidos

Acta Cirúrgica Brasileira, 2007
PURPOSE: To evaluate the effects of glutamine (L-Gln) or whey-protein supplementation on CD4+ and CD8+ lymphocytes in alloxan-induced diabetic rats. METHODS: Thirty-two healthy male Wistar rats were used in the experiment.
Renato Motta Neto, Sergio Botelho Guimarães, Sônia Leite da Silva, José Napoleão da Cruz, Thiago Dias, Paulo Roberto Leitão de Vasconcelos   +5 more
doaj   +1 more source

Streptococcus pneumoniae serotype 1 capsular polysaccharide induces CD8CD28 regulatory T lymphocytes by TCR crosslinking. [PDF]

PLoS Pathogens, 2009
Zwitterionic capsular polysaccharides (ZPS) of commensal bacteria are characterized by having both positive and negative charged substituents on each repeating unit of a highly repetitive structure that has an alpha-helix configuration.
Janina Mertens, Mario Fabri, Alessandra Zingarelli, Torsten Kubacki, Sonja Meemboor, Laura Groneck, Jens Seeger, Martina Bessler, Helena Hafke, Margarete Odenthal, Joan G Bieler, Christoph Kalka, Jonathan P Schneck, Hamid Kashkar, Wiltrud M Kalka-Moll   +14 more
doaj   +1 more source

Enhanced CXCR4 Expression of Human CD8Low T Lymphocytes Is Driven by S1P4

Frontiers in Immunology, 2021
Although the human immune response to cancer is naturally potent, it can be severely disrupted as a result of an immunosuppressive tumor microenvironment.
Tobias Burkard, Caroline Dreis, Martina Herrero San Juan, Meik Huhn, Andreas Weigert, Josef M. Pfeilschifter, Heinfried H. Radeke   +6 more
doaj   +1 more source

Mice Deficient in Nucleoporin Nup210 Develop Peripheral T Cell Alterations

Frontiers in Immunology, 2018
The nucleopore is an essential structure of the eukaryotic cell, regulating passage between the nucleus and cytoplasm. While individual functions of core nucleopore proteins have been identified, the role of other components, such as Nup210, are poorly ...
Annemarie van Nieuwenhuijze, Annemarie van Nieuwenhuijze, Oliver Burton, Oliver Burton, Pierre Lemaitre, Pierre Lemaitre, Alice E. Denton, Ana Cascalho, Ana Cascalho, Rose E. Goodchild, Rose E. Goodchild, Bert Malengier-Devlies, Bert Malengier-Devlies, Bénédicte Cauwe, Bénédicte Cauwe, Michelle A. Linterman, Stephanie Humblet-Baron, Stephanie Humblet-Baron, Adrian Liston, Adrian Liston   +19 more
doaj   +1 more source

IL-27 shapes the immune properties of human astrocytes and their impact on encountered human T lymphocytes

Journal of Neuroinflammation, 2022
Background Interleukin-27 (IL-27) can trigger both pro- and anti-inflammatory responses. This cytokine is elevated in the central nervous system (CNS) of multiple sclerosis (MS) patients, but how it influences neuroinflammatory processes remains unclear.
Florent Lemaître, Negar Farzam-kia, Ana Carmena Moratalla, Yves Carpentier Solorio, Marie-Laure Clenet, Olivier Tastet, Aurélie Cleret-Buhot, Jean Victor Guimond, Elie Haddad, Pierre Duquette, J. Marc Girard, Alexandre Prat, Catherine Larochelle, Nathalie Arbour   +13 more
doaj   +1 more source

Molecular signatures distinguish human central memory from effector memory CD8 T cell subsets [PDF]

, 2005
Memory T cells are heterogeneous in terms of their phenotype and functional properties. We investigated the molecular profiles of human CD8 naive central memory (T(CM)), effector memory (T(EM)), and effector memory RA (T(EMRA)) T cells using gene ...
Freeman, Tom, Hasegawa, Hitoshi, Willinger, Tim, Callan, Margaret F C, McMichael, Andrew J, Willinger, T, Freeman, T, Callan, MF, Hasegawa, H, Mcmichael, Andrew   +9 more
core   +1 more source

Gamma interferon-dependent clearance of cytomegalovirus infection in salivary glands [PDF]

, 1992
Cytomegalovirus (CMV), similar to other members of the Herpesviridae family, can establish both persistent and latent infections. Each of the CMVs that are found in many animal species replicates in the salivary gland, and oral secretion represents a ...
Pavic, Ivica, Koszinowski, Ulrich H., Koszinowski, U H, Lucin, Pero, Polic, Bojan, Jonjic, Stipan   +5 more
core   +2 more sources

Overexpression of PD-1 and CD39 in tumor-infiltrating lymphocytes compared with peripheral blood lymphocytes in triple-negative breast cancer.

PLoS ONE, 2022
Background and aimGrowing evidence highlighted the primary role of the immune system in the disease course of triple-negative breast cancer (TNBC). The study aim was to investigate the expression of PD-1 and CD39 on CD4+ and CD8+ cells infiltrating tumor
Asmaa M Zahran, Amal Rayan, Zeinab Albadry M Zahran, Wael M Y Mohamed, Dalia O Mohamed, Mona H Abdel-Rahim, Omnia El-Badawy   +6 more
doaj   +1 more source