Results 11 to 20 of about 419,552 (297)

Respiratory Syncytial Virus Infection Induces Expression of Inducible Nitric Oxide Synthase, CD3, and CD8 in Naturally Occurring Pneumonia in Lambs

open access: yesActa Veterinaria, 2021
Respiratory syncytial virus (RSV) is an RNA virus that belongs to the Pneumovirus genus of the Paramyxoviridae family. The aim of this study was to evaluate the expressions of inducible nitric oxide synthetase (iNOS), CD3 (pan T cells), and CD8 ...
Yaman Turan, Aydemir Ceyhun
doaj   +1 more source

Artificial intelligence-based comprehensive analysis of immune-stemness-tumor budding profile to predict survival of patients with pancreatic adenocarcinoma

open access: yesCancer Biology & Medicine, 2023
Objective: Pancreatic ductal adenocarcinoma (PDAC) is an aggressive malignancy. CD8+ T cells, cancer stem cells (CSCs), and tumor budding (TB) have been significantly correlated with the outcome of patients with PDAC, but the correlations have been ...
Tianxing Zhou   +11 more
doaj   +1 more source

Digital image analysis for estimating stromal CD8+ tumor-infiltrating lymphocytes in lung adenocarcinoma

open access: yesJournal of Pathology Informatics, 2021
Background: Stromal CD8+ tumor-infiltrating lymphocytes (TILs) are an important prognostic and predictive indicator in non-small cell lung cancer (NSCLC).
Iny Jhun   +5 more
doaj   +1 more source

CD8+ Lymphomatoid Papulosis [PDF]

open access: yesAnnals of Dermatology, 2011
Lymphomatoid papulosis (LyP) is defined as a histologically malignant, but clinically benign condition. It can appear as erythematous pink to purple papules or nodules. Immunophenotyping studies of the lymphomatoid papulosis lesions have shown a predominance of a CD4 expression and negativity for CD8.
You Chan Kim, Ji Hyun Sim
openaire   +3 more sources

Collisional variant of CD8+ mycosis fungoides and indolent CD8+ lymphoid proliferation [PDF]

open access: yesJAAD Case Reports, 2020
Abstract: CD8+ lymphoid infiltrates of the skin are classified into different subtypes with variable prognoses and treatment options. Here, we present a patient with CD8+ mycosis fungoides who developed CD8+ indolent lymphoid proliferation in a background of conventional plaque stage CD8+ mycosis fungoides.
Larisa J. Geskin   +3 more
openaire   +4 more sources

Robust antigen-specific CD8 T cell tolerance to a model prostate cancer neoantigen

open access: yesOncoImmunology, 2020
Immunotherapy has shown limited success in prostate cancer; this may be partially explained by its immunosuppressive tumor microenvironment (TME). Although androgen-deprivation therapy (ADT), the most common treatment for prostate cancer, initially ...
Zoila A. Lopez-Bujanda   +5 more
doaj   +1 more source

The Immunomodulatory Effects of Ginger (Zingiber officinale) Extract on CD4 and CD8 Expression in Spleen of Diabetic Rats

open access: yesNamık Kemal Tıp Dergisi, 2023
Aim:This study aims to examine the changes of the ginger extract treatment on CD4 and CD8 expressions in the spleen tissue of rats, in which the experimental diabetes was induced with streptozotocin.Materials and Methods:Forty Wistar albino rats were ...
Buket BAKIR
doaj   +1 more source

CD8+ and CD8- NKT Cells Exhibit Phenotypic Changes During Pregnancy

open access: yesImmunological Investigations, 2022
NKT cell population is a relatively well-characterized immune cell subset. Numerous publications have characterized the phenotypical features of its subpopulations even in human pregnancy. Nevertheless, there have not been studies investigating the distribution of the NKT cells based on the surface presence of the CD8 receptor.
Matyas Meggyes   +4 more
openaire   +4 more sources

The expression of SP263 in muscle invasive bladder carcinoma and its relationship with clinicopathological features

open access: yesIndian Journal of Pathology and Microbiology, 2023
Context: The expression of programmed cell death ligand1 (PDL1) is a research hotspot of immunotherapy. The treatment targeted for its expression has shown effectiveness in many tumors. Objective: The aim of the study was to determine PD-L1 expression in
Yanfeng Bai   +6 more
doaj   +1 more source

Cd8+ but Not Cd8− Dendritic Cells Cross-Prime Cytotoxic T Cells in Vivo [PDF]

open access: yesThe Journal of Experimental Medicine, 2000
Bone marrow–derived antigen-presenting cells (APCs) take up cell-associated antigens and present them in the context of major histocompatibility complex (MHC) class I molecules to CD8+ T cells in a process referred to as cross-priming. Cross-priming is essential for the induction of CD8+ T cell responses directed towards antigens not expressed in ...
den Haan, J M, Lehar, S M, Bevan, M J
openaire   +4 more sources

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