Results 211 to 220 of about 394,438 (273)

Tumor Microenvironment On‐A‐Chip and Single‐Cell Analysis Reveal Synergistic Stromal–Immune Crosstalk on Breast Cancer Progression

Advanced Science, EarlyView.
Using a 3D tumor microenvironment (TME)‐on‐a‐chip model, tumor–stromal–immune crosstalk in triple‐negative breast cancer is studied, revealing the TME's combinatorial effect on cancer progression. Integrating single‐cell transcriptomic analysis demonstrates metabolic reprogramming via the kynurenine pathway, highlighting the complex TME cellular ...
Kalpana Ravi, Yining Zhang, Lydia Sakala, Twinkle Jina Minette Manoharan, Barbara Pockaj, Joshua LaBaer, Jin G. Park, Mehdi Nikkhah   +7 more
wiley   +1 more source

Two-plex <i>in vivo</i> molecular imaging in the second near-infrared window for immunotherapeutic response. [PDF]

Theranostics
Sun Y, Li R, Cai Y, Liu Y, Wang P, Wu M, Zhang X, Liao N, Zhang C, Zheng A, Xu H, Zeng R, Zeng Y, Liu X.   +13 more
europepmc   +1 more source

EVIDENCE THAT AN ANTHRACYCLINE-ANTI-CD8 IMMUNOCONJUGATE, IDARUBICIN-ANTI-LY-2.1, PROLONGS HEART ALLOGRAFT SURVIVAL IN MICE

, 1993
Patricia L. Mottram, Geoffrey A. Pietersz, Mark J. Smyth, Lisa J. Purcell, G. J. A. Clunie, Ian F. C. McKenzie   +5 more
openalex   +1 more source

Selective depletion of CD8+ T lymphocytes for prevention of graft- versus-host disease after allogeneic bone marrow transplantation [PDF]

, 1990
Richard E. Champlin, W. G. Ho, J. Gajewski, StephenA. Feig, M. Burnison, G Holley, Peter Greenberg, K Lee, Irene Schmid, J. Giorgi   +9 more
openalex   +1 more source

Single‐Cell Atlas Reveals Tumorigenic Profiles and Immune Dynamics of Adrenal Incidentalomas

Advanced Science, EarlyView.
Single‐cell RNA sequencing reveals cellular heterogeneity in adrenal incidentalomas, identifying distinct tumor cell populations. Clusterin is recognized as a biomarker for adrenocortical tumors, correlating with established markers. MYCN‐positive clusters in pheochromocytomas indicated poorer survival.
Meng Wang, Guangmin Zheng, Xiaoyong Hu, Feng Tian, Tuo Li, Zheng Zhang, Kan Gong, Shiwei Chen, Lin Yuan, Yu Qi, Lin Li, Daofu Cheng, Liu Liu, Fuqiang Liu, Yujing Sun, Xiangdong Fang, Ruxing Zhao, Bing Liu, Chao Zhang   +18 more
wiley   +1 more source

A gold nanoparticle/peptide vaccine designed to induce SARS-CoV-2-specific CD8 T cells: a double-blind, randomized, phase 1 study in Switzerland. [PDF]

BMC Infect Dis
Besson J, Audran R, Karlen M, Miauton A, Hajjami HM, Warpelin-Decrausaz L, Sene L, Schaufelberger S, Faivre V, Faouzi M, Hartley MA, Spertini F, Genton B.   +12 more
europepmc   +1 more source

A CLDN18.2‐Targeted Nanoplatform Manipulates Magnetic Hyperthermia Spatiotemporally for Synergistic Immunotherapy in Gastric Cancer

Advanced Science, EarlyView.
CLDN18.2 is a highly selective biomarker exposed in gastric cancer. A CLDN18.2‐specific antibody 1D5 conjugated fluorescence‐magnetic nanoparticle is developed for image‐guided precision theragnostics. Under the assistance of sensitive FMI and deep‐penetrating MPI for tracing and timing the optimal nanoparticle dosage, combining α‐PD1 therapy with ...
Xueying Wang, Hui Hui, Jing Han, Ting Guo, Yiding Wang, Lin Meng, Cong Chen, Jie He, Xiaoyong Guo, Fuyu Zhong, Hong Du, Jie Tian, Xiaofang Xing, Yang Du, Jiafu Ji   +14 more
wiley   +1 more source

Changes in the immune index before and after surgery in urinary malignancy patients with AIDS. [PDF]

Sci Rep
Xue W, Zhang Y, Zhang M, Huang Z.
europepmc   +1 more source

Tumor‐Adhesive Chitosan‐Derived Multi‐Immune Agonist Unleashes Strong and Durable Anti‐Cancer Immunity

Advanced Science, EarlyView.
A tumor‐adhesive chitosan‐derived immune agonist TACTIC is developed for strong and durable anti‐tumor immunity. The immune agonist exhibits multi‐targets and modulates both tumor cell immunogenicity and pro‐inflammatory responses in immune cells, thereby potentiating the therapeutic efficacy of clinical radiotherapy.
Huilan He, Liang Liu, Yun Zheng, Jinlong Ji, Li Cao, Chunlian Ye, Yu Sun, Ying Zhang, Zhiyuan Zhong   +8 more
wiley   +1 more source

In vivo armed macrophages curb liver metastasis through tumor-reactive T-cell rejuvenation. [PDF]

Nat Commun
Notaro M, Borghetti M, Bresesti C, Giacca G, Kerzel T, Mercado CM, Beretta S, Monti M, Merelli I, Iaia S, Genua M, Annoni A, Canu T, Cristofori P, Degl'Innocenti S, Sanvito F, Rancoita PMV, Ostuni R, Gregori S, Naldini L, Squadrito ML.   +20 more
europepmc   +1 more source