Results 101 to 110 of about 25,955 (200)

Exosomes of Epstein-Barr Virus-Associated Gastric Carcinoma Suppress Dendritic Cell Maturation

Microorganisms, 2020
The Epstein-Barr virus (EBV)-associated gastric carcinoma (EBVaGC) is characterized by the infiltration of lymphocytes and a unique tumor microenvironment. Exosomes from cancer cells are essential for intercellular communication.
Munetoshi Hinata, Akiko Kunita, Hiroyuki Abe, Yasuyuki Morishita, Kei Sakuma, Hiroharu Yamashita, Yasuyuki Seto, Tetsuo Ushiku, Masashi Fukayama   +8 more
doaj   +1 more source

Persistence within dendritic cells marks an antifungal evasion and dissemination strategy of Aspergillus terreus [PDF]

, 2017
Aspergillus terreus is an airborne human fungal pathogen causing life-threatening invasive aspergillosis in immunocompromised patients. In contrast to Aspergillus fumigatus, A.
A Espinel-Ingroff, A Margalit, AJ Masterson, AR Mantegazza, C Lass-Flörl, C Lass-Flörl, E Geib, FJ Pastor, FS Taccone, I Leonhardt, J Vega-Ramos, K Larsson, KS Gregg, M Gressler, R Thakur, RM Steinman, S Bozza, S Slesiona, S Slesiona, SJ Martin, SJ Park, SJ Park, SJ Park, SL Newman, T Heinekamp, TM Hohl, V Espinosa, V Gafa, WJ Steinbach, Y Schmiedel, ZG Ramirez-Ortiz   +30 more
core   +2 more sources

The dysregulation of innate immunity by Porphyromonas gingivalis in the etiology of Alzheimer's disease

Journal of Internal Medicine, Volume 299, Issue 3, Page 328-348, March 2026.
Abstract The etiology of Alzheimer's disease (AD) remains under active debate. In this perspective, we explore the hypothesis that a primarily infection‐caused chronic dysregulation and weakening of human innate immunity via the underexpression, degradation, and inactivation of innate immune proteins necessary for direct antimicrobial effects and ...
Annelise E. Barron, Jennifer S. Lin, Mark I. Ryder, Peter Bergman   +3 more
wiley   +1 more source

Semi Mature Blood Dendritic Cells Exist in Patients with Ductal Pancreatic Adenocarcinoma Owing to Inflammatory Factors Released from the Tumor

, 2010
Background: Much evidence exists regarding the fact that blood DCs, both myeloid DCs (MDCs) and plasmacytoid DCs (PDCs), are negatively affected in different types of cancer, with both reduced numbers and impaired functionality.
Borch, Kurt, Larsson, Marie, Messmer, Davorka, Sandström, Per, Spångeus, Anna, Tjomsland, Vegard   +5 more
core   +1 more source

Expresión de marcadores en células dendríticas de pacientes chagásicos crónicos estimuladas con la proteína KMP-11 y el péptido K1 de Trypanosoma cruzi

Biomédica: revista del Instituto Nacional de Salud, 2007
Introducción. La proteína de membrana 11 de kinetoplástidos, KMP-11, de Trypanosoma cruzi induce inmunidad humoral y celular en ratones capaz de conferir protección frente al reto con el parásito. Objetivo.
Sandra Paola Santander, Adriana Cuéllar, María del Carmen Thomas, Fanny Guzmán, Alberto Gómez, Manuel Carlos López, Concepción Puerta   +6 more
doaj   +1 more source

Curse of dimensionality reduction in max-plus based approximation methods: theoretical estimates and improved pruning algorithms

, 2011
Max-plus based methods have been recently developed to approximate the value function of possibly high dimensional optimal control problems. A critical step of these methods consists in approximating a function by a supremum of a small number of ...
Gaubert, Stephane, McEneaney, William, Qu, Zheng   +2 more
core   +2 more sources

The role of Microenvironment in tumorigenesis. Focus on dendritic cells in human papillomavirus E6, E7-transformed keratinocytes [PDF]

, 2015
The inception of tumor microenvironment (TME), a complex and dynamic system constituted by different types of cells engaged by tumor and extracellular matrix surrounding cancer cells, is a way for them to elude the immune surveillance.
Accardi, Rosita, CHIANTORE, Maria Vincenza, Fiorucci, Gianna, IULIANO, MARCO, MANGINO, GIORGIO, ROMEO, Giovanna, Tommasino, Massimo   +6 more
core   +1 more source

Soluble CD83 Alleviates Experimental Autoimmune Uveitis by Inhibiting Filamentous Actin-Dependent Calcium Release in Dendritic Cells

Frontiers in Immunology, 2018
Soluble CD83 (sCD83) is the extracellular domain of the membrane-bound CD83 molecule, and known for its immunoregulatory functions. Whether and how sCD83 participates in the pathogenesis of uveitis, a serious inflammatory disease of the eye that can ...
Wei Lin, Wei Lin, Wei Lin, Konrad Buscher, Konrad Buscher, Beibei Wang, Zhichao Fan, Nannan Song, Peng Li, Yingying Yue, Bingqing Li, Cuiling Li, Hongsheng Bi   +12 more
doaj   +1 more source

Tissue micro array analysis of ganglioside N-glycolyl GM3 expression and signal transducer and activator of transcription (STAT)-3 activation in relation to dendritic cell infiltration and microvessel density in non-small cell lung cancer

BMC Cancer, 2009
Background Tumor immune escape and angiogenesis contribute to tumor progression, and gangliosides and activation of signal transducer and activator of transcription (STAT)-3 are implicated in these processes.
de Gruijl Tanja D, van der Valk Paul, Ruiz Mariëlle, van Cruijsen Hester, Giaccone Giuseppe   +4 more
doaj   +1 more source

Dendritic-Cell (DC)-Based Immunotherapy: Tumor Endothelial Marker 8 (TEM8) Gene Expression of DC Vaccines Correlates with Clinical Outcome [PDF]

, 2008
\ud Previous studies have shown that tumor-endothelial markers (TEMs) are upregulated in immunosuppressive, pro-angiogenic dendritic cells (DCs) found in tumor microenvironments. \ud We reported that pro-angiogenic monocyte-derived DCs (Mo-DCs), utilized
Bolli, Elisabetta, Ridolfi, R., Venanzi, F.M.   +2 more
core