Results 91 to 100 of about 26,169 (207)

Immunomodulatory effects of heat killed 'Mycobacterium obuense' on human blood dendritic cells [PDF]

, 2017
Heat-killed (HK) Mycobacterium obuense is a novel immunomodulator, currently undergoing clinical evaluation as an immunotherapeutic agent in the treatment of cancer. Here, we examined the effect of in vitro exposure to HK M. obuense on the expression of
Achkar, Marcel, Akle, Charles, Bahr, Georges, Bazzi, Samer, Modjtahedi, Helmout, Mudan, Satvinder   +5 more
core   +1 more source

Oxidative Stress in the Tumor Immune Microenvironment: Mechanisms and Therapeutic Perspectives

MedComm – Oncology, Volume 5, Issue 2, June 2026.
Oxidative stress is involved in several key processes in cancer, including redox regulation, DNA damage, post‐translational modifications, transcriptional regulation, epigenetic modifications, metabolic reprogramming, cell death, and immune modulation. These mechanisms collectively influence tumor progression, immune evasion, and therapeutic responses,
Zhen Wang, Bowen Li, Pan Tang, Fanchen Yan, Shuxin Wang, Guiying Leng, Panduo Dawa, Yuansi Chen, Yihan Guo, Pan Yang, Yi Li, Siyu Liu, Erdan Dong, Siyuan Qin, Zhoufeng Wang   +14 more
wiley   +1 more source

The CD83 reporter mouse elucidates the activity of the CD83 promoter in B, T, and dendritic cell populationsin vivo [PDF]

Proceedings of the National Academy of Sciences, 2008
CD83 is the major surface marker identifying mature dendritic cells (DCs). In this study, we report the generation of reporter mice expressing EGFP under the control of the CD83 promoter. We have used these mice to characterize CD83 expression by various immune system cell types bothin vivoandex vivoand under steady-state conditions and in response to ...
Matthias, Lechmann, Naomi, Shuman, Andrew, Wakeham, Tak W, Mak   +3 more
openaire   +2 more sources

Differential expression of cell surface markers in response to 2,4-dinitrofluorobenzene in RAW 264.7 and primary immune cells [PDF]

BMB Reports, 2012
We evaluated the expression of the costimulatory moleculesCD80 and CD83 and major histocompatibility (MHC) class IIinduced by 2,4-dinitrofluorobenzene (DNFB) in the RAW264.7 macrophage cell line.
Dongbum Kim1, Min Chul Park1, Byoung Kwon Park1, Sanghoon Kwon2, Joon-Ho Choi3, Hyun-Jong Kim4, Soo-Young Choi5, Jinseu Park5, Younghee Lee6 & Hyung-Joo Kwon1,2,*
doaj  

CTLA4 is expressed on mature dendritic cells derived from human monocytes and influences their maturation and antigen presentation [PDF]

, 2011
Background Dendritic cells (DCs) initiate immune responses through their direct interaction with effector cells. However, the mechanism by which DC activity is regulated is not well defined. Previous studies have shown that CTLA4 on T cells regulates DCs
Ni Zhen H, Vollenhoven Annika V, Anton Doina, Fan Zhong Z, Wang Xiong B, Chen Xiao F, Lefvert Ann K   +6 more
core   +2 more sources

Neoadjuvant Immunochemotherapy Increases the Abundance of Tertiary Lymphoid Structures and Lymphocyte Subpopulations Is Associated With Prognosis of Esophageal Squamous Cell Carcinoma

Cancer Medicine, Volume 15, Issue 5, May 2026.
ABSTRACT Neoadjuvant immunochemotherapy (NIC) has emerged as a promising strategy for esophageal squamous cell carcinoma (ESCC). However, its impact on tertiary lymphoid structures (TLSs) and the immune microenvironment remains to be fully elucidated. We retrospectively analyzed 50 ESCC patients treated with NIC (n = 25) or chemotherapy alone (n = 25 ...
Ning Li, Xiaoyan Zhang, Xupeng Tang, Juanning Shen, Qing Qi, Huili Wu, Yuze Zhao, Shuo Wang   +7 more
wiley   +1 more source

Prevention and Treatment of Experimental Autoimmune Encephalomyelitis by Soluble CD83 [PDF]

The Journal of Experimental Medicine, 2004
CD83 is up-regulated on the surface of dendritic cells (DCs) during maturation and has been widely used as a marker for mature DCs. Recently, we reported the recombinant expression of the extracellular immunoglobulin domain of human CD83 (hCD83ext). Using this soluble form of CD83, allogeneic as well as specific cytotoxic T lymphocyte proliferation ...
Zinser, Elisabeth, Lechmann, Matthias, Golka, Antje, Lutz, Manfred B., Steinkasserer, Alexander   +4 more
openaire   +2 more sources

SUBTYPE CHARACTERICS OF DENDRITIC CELLS FROM PERIPHERAL BLOOD OF PATIENTS WITH RHEUMATOID ARTHRITIS

Медицинская иммунология, 2014
. Characteristics of myeloid and plasmacytoid dendritic cells from peripheral blood were studied in healthy donors and patients with rheumatoid arthritis (RA).
S. A. Falaleeva, V. V. Kurilin, N. S. Shkaruba, O. A. Chumasova, A. E. Sizikov, S. V. Sennikov   +5 more
doaj   +1 more source

Staphylococcus aureus Sb‐1 Bacteriophage Alters Frequency and Subset Distribution of Human Innate Lymphoid Cells

Allergy, EarlyView.
Ramazan Rozumbetov, Ismail Ogulur, Anja Heider, Anna Globinska, Nina Chanishvili, Elene Kakabadze, Marina Goderdzishvili, Nino Grdzelishvili, Nata Bakuradze, Moelong Yu, Tamara Aripova, Adolat Ismailova, Nikolaos Papadopoulos, Mubeccel Akdis, Cezmi A. Akdis   +14 more
wiley   +1 more source

Comprehensive Evaluation of the Anti‐Inflammatory Activity of Ling‐Zhi‐8 (LZ‐8) In Vitro and a Rheumatoid Arthritis Animal Model

Food Science &Nutrition, Volume 14, Issue 5, May 2026.
LZ‐8 reduced IL‐6 and COX‐2 in LPS‐stimulated macrophages, partly by inhibiting MyD88‐mediated JNK‐MAPK signaling. LZ‐8 reduced inflammation and swelling in the ankle and palm of the feet in the animal model. High‐dose LZ‐8 reduced synovial hyperplasia, and all doses protected articular cartilage.
Shao‐Wen Hung, Po‐Jung Tsai, Cheng‐Yao Yang, Lu‐Te Chuang   +3 more
wiley   +1 more source