Results 91 to 100 of about 20,106 (166)

Tissue micro array analysis of ganglioside N-glycolyl GM3 expression and signal transducer and activator of transcription (STAT)-3 activation in relation to dendritic cell infiltration and microvessel density in non-small cell lung cancer

BMC Cancer, 2009
Background Tumor immune escape and angiogenesis contribute to tumor progression, and gangliosides and activation of signal transducer and activator of transcription (STAT)-3 are implicated in these processes.
de Gruijl Tanja D, van der Valk Paul, Ruiz Mariëlle, van Cruijsen Hester, Giaccone Giuseppe   +4 more
doaj   +1 more source

Analysis of CD83 antigen expression in human breast fibroadenoma and adjacent tissue

São Paulo Medical Journal
CONTEXT AND OBJECTIVE: Dendritic cell maturation is considered essential for starting an immune response. The CD83 antigen is an important marker of dendritic cell maturation.
Marcus Nascimento Borges, Gil Facina, Ismael Dale Cotrin Guerreiro Silva, Angela Flávia Logullo Waitzberg, Afonso Celso Pinto Nazario   +4 more
doaj   +1 more source

The effect of Propionibacterium acnes on maturation of dendritic cells derived from acne patients' peripherial blood mononuclear cells.

Folia Histochemica et Cytobiologica, 2009
Propionibacterium acnes (P. acnes) has been implicated in the pathogenesis of acne vulgaris which is the most common cutaneous disorder. It has a proinflammatory activity and takes part in immune reactions modulating the Th1/Th2 cellular response.
Maria Juszkiewicz-Borowiec, Alina Olender, Jacek Tabarkiewicz, Anna Michalak-Stoma, Filip Stoma, Aldona Pietrzak, Piotr Pozarowski, Małgorzata Bartkowiak-Emeryk   +7 more
doaj   +1 more source

NK cells are negatively regulated by sCD83 in experimental autoimmune uveitis

Scientific Reports, 2017
Natural killer (NK) cells represent a subset of lymphocytes that contribute to innate immunity and have been reported to play a role in autoimmune uveitis. However, the mechanisms regulating NK cellular function in this condition remain unclear.
Wei Lin, Xuejing Man, Peng Li, Nannan Song, Yingying Yue, Bingqing Li, Yuanbin Li, Yufei Sun, Qiang Fu   +8 more
doaj   +1 more source

Herpes simplex virus type 1 induces CD83 degradation in mature dendritic cells with immediate-early kinetics via the cellular proteasome

, 2007
Mature dendritic cells (DCs) are the most potent antigen-presenting cells within the human immune system. However, Herpes simplex virus type 1 (HSV-1) is able to interfere with DC biology and to establish latency in infected individuals.
Roger D. Everett, Mirko Kummer, Kummer, M., Coffin, R.S., Nadine M. Turza, Chris Boutell, Petra Muhl-Zurbes, Alexander T. Prechtel, Steinkasserer, A., Turza, N.M., Muhl-Zurbes, P., Matthias Lechmann, Robert S. Coffin, Lechmann, M., Everett, R.D., Prechtel, A.T., Boutell, C., Alexander Steinkasserer   +17 more
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Synergy between Vitamin D3 and Toll-Like Receptor Agonists Regulates Human Dendritic Cell Response during Maturation

Clinical and Developmental Immunology, 2013
Human dendritic cells (DC) can be differentiated from blood monocytes in the presence of GM-CSF and IL-4 and matured by lipopolysaccharide (LPS). Vitamin D3 inhibits the maturation of human DC measured by changes in surface expression of HLA-DR, CD14 ...
Anne Brosbøl-Ravnborg, Bettina Bundgaard, Per Höllsberg   +2 more
doaj   +1 more source

Soluble CD83 ameliorates experimental colitis in mice

, 2014
The physiological balance between pro- and anti-inflammatory processes is dysregulated in inflammatory bowel diseases (IBD) as in Crohn's disease and ulcerative colitis. Conventional therapy uses anti-inflammatory and immunosuppressive corticosteroids to
Becker, C., Debenedette, M. A., Pommer, A. J., Steinkasserer, A., Eckhardt, J., Döbbeler, M., Nicolette, C., Ostalecki, C., Kreiser, S., Mak, T. W., Lechmann, M., Tcherepanova, I. Y., Zinser, E., Günther, C.   +13 more
core   +1 more source

Calcitonin Gene-Related Peptide Effects on Phenotype and IL-12 Production of Monocyte-Derived Dendritic Cells in Rheumatoid Arthritis Patients [PDF]

Iranian Journal of Basic Medical Sciences, 2010
Objective(s)Recent studies on human indicate that the introduction of therapeutic use of tolerogenic dendritic cell (DC) for chronic inflammatory conditions is imminent.
Azam Brook, Nafise Tabasi, Seyed-Mohammad Moazzeni, Zahra Mirfeizi, Zahra Rezaieyazdi, Maryam Rastin, Javid Morad Abbasi, Mahmoud Mahmoudi   +7 more
doaj  

Transdifferentiation of neutrophils facilitates the establishment of infection by Leishmania donovani parasites

Infection and Immunity
Neutrophil transdifferentiation involves the acquisition of dendritic cell-like properties, challenging the traditional view of neutrophils being solely phagocytes. The presence of transdifferentiated neutrophils is established in Visceral Leishmaniasis,
Madhurima Roy, Aniruddha Bagchi, Chaitali Karmakar, Mitali Chatterjee   +3 more
doaj   +1 more source

免疫担当細胞におけるCD83の機能と皮膚疾患との関連 [PDF]

CD83の生体内での機能を明らかにするため、CD83ノックアウトマウスを使用した。CD83ノックアウトマウス由来の細胞におけるMHC class II分子の発現量を検討したところ、CD83ノックアウトマウス由来抗原提示細胞ではCD83の膜表面での発現が低下しており、CD83欠損B細胞では野生型マウス由来B細胞に比べて約50%の減少が認められた。CD23やCD86の発現低下も認められた。しかしながら、細胞内のMHC class IIの発現量は野生型マウスと同等かむしろ亢進していた ...
藤本, 学, 1766, 90272591
core   +1 more source