Results 71 to 80 of about 26,169 (207)

PHENOTYPIC PECULIARITIES OF DENDRITIС CELLS DIFFERENTIATED FROM BLOOD MONOCYTES IN PATIENTS WITH KIDNEY CANCER

Медицинская иммунология, 2018
The aim of the study was to investigate the phenotypic features of dendritic cell (DCs) differentiated from peripheral blood monocytes in patients with kidney cancer (KC).
A. A. Savchenko, A. G. Borisov, I. V. Kudryavtsev, I. I. Gvozdev, A. V. Moshev   +4 more
doaj   +1 more source

Dendritic-Cell (DC)-Based Immunotherapy: Tumor Endothelial Marker 8 (TEM8) Gene Expression of DC Vaccines Correlates with Clinical Outcome [PDF]

, 2008
\ud Previous studies have shown that tumor-endothelial markers (TEMs) are upregulated in immunosuppressive, pro-angiogenic dendritic cells (DCs) found in tumor microenvironments. \ud We reported that pro-angiogenic monocyte-derived DCs (Mo-DCs), utilized
Bolli, Elisabetta, Ridolfi, R., Venanzi, F.M.   +2 more
core  

Direct Activation of Human Dendritic Cells by Particle-Bound but Not Soluble MHC Class II Ligand [PDF]

, 2013
Dendritic cells (DCs) are key activators of cellular immune responses through their capacity to induce naïve T cells and sustained effector T cell responses. This capacity is a function of their superior efficiency of antigen presentation via MHC class I
Baleeiro, R.B. (Renato), Barbuto, J.A. (José), Dähne, L. (Lars), Lademann, J. (Jürgen), Walden, P. (Peter), Wiesmüller, K.H. (Karl Heinz)   +5 more
core   +1 more source

Plasma Protein Analysis for Biomarker Discovery in Lung Cancer Treated With Atezolizumab Combination Therapy in J‐TAIL‐2

Cancer Science, EarlyView.
BLURB FOR ETOC: The J‐TAIL‐2 study (NCT04501497) evaluated the efficacy and safety of atezolizumab, an anti‐programmed death‐ligand 1, plus chemotherapy in patients with non‐small cell lung cancer (NSCLC) and extensive‐stage small cell lung cancer (ES‐SCLC) in real‐world settings.
Yasushi Goto, Makoto Nishio, Kadoaki Ohashi, Atsushi Osoegawa, Eiki Kikuchi, Hideharu Kimura, Junichi Shimizu, Eisaku Miyauchi, Hiroshige Yoshioka, Ichiro Yoshino, Toshihiro Misumi, Yasutaka Watanabe, Nobuyuki Katakami, Akira Kisohara, Masafumi Yamaguchi, Hirotaka Kuroki, Masamichi Sugimoto, Hisao Ashimura, Misa Tanaka, Akihiko Gemma   +19 more
wiley   +1 more source

Tumor necrosis factor-alpha regulates the expression of inducible costimulator receptor ligand on CD34+ progenitor cells during differentiation into antigen presenting cells [PDF]

, 2001
The inducible costimulator receptor (ICOS) is a third member of the CD28 receptor family that regulates T cell activation and function. ICOS binds to a newly identified ligand on antigen presenting cells different from the CD152 ligands CD80 and CD86. We
Aicher, A, Clark, EA, Daemen, K, Hayden-Ledbetter, M, Irgang, M, Korner, I, Ledbetter, JA, Pezzutto, A, Richter, G, Westermann, J   +9 more
core  

Myeloid but not plasmacytoid blood DCs possess Th1 polarizing and Th1/Th17 recruiting capacity in psoriasis [PDF]

, 2017
K
Baráth, Sándor, Bácsi, Attila, Béke, Gabriella, Dajnoki, Zsolt, Gaál, János, Gáspár, Krisztián, Jenei, Adrienn, Kapitány, Anikó, Khasawneh, Ahmad, Medgyesi, Barbara, Pogácsás, Lilla, Pázmándi, Kitti Linda, Szegedi, Andrea   +12 more
core   +1 more source

Ligand‐specific tuning of CLEC10A signalling strength and dendritic cell responses through engagement of different GalNAc‐containing glycan structures

The FEBS Journal, EarlyView.
The authors investigated the effects of various glycan ligands for CLEC10A, a lectin receptor expressed on dendritic cells (DCs). Monocyte‐derived DCs were stimulated with glycan‐conjugated dendrimers in combination with the TLR1/2 ligand Pam3CysK4, and responses were investigated at the mRNA and protein level.
Nadia L. van der Meijs, Remi Hatinguais, Mike de Kok, R. J. Eveline Li, Tesfay M. Godefa, Victor L. J. L. Thijssen, Yvette van Kooyk, Sandra J. van Vliet   +7 more
wiley   +1 more source

CD83 Expression Influences CD4+ T Cell Development in the Thymus [PDF]

Cell, 2002
T lymphocyte selection and lineage commitment in the thymus requires multiple signals. Herein, CD4+ T cell generation required engagement of CD83, a surface molecule expressed by thymic epithelial and dendritic cells. CD83-deficient (CD83-/-) mice had a specific block in CD4+ single-positive thymocyte development without increased CD4+CD8+ double- or ...
Fujimoto, Yoko, Tu, LiLi, Miller, Ann S., Bock, Cheryl, Fujimoto, Manabu, Doyle, Carolyn, Steeber, Douglas A., Tedder, Thomas F.   +7 more
openaire   +2 more sources

Sebaceous gland rich skin is characterized by TSLP expression and distinct immune surveillance which is disturbed in rosacea [PDF]

, 2017
K
Bácsi, Attila, Béke, Gabriella, Bíró, Tamás, Dajnoki, Zsolt, Gáspár, Krisztián, Hendrik, Zoltán, Juhász, István, Kapitány, Anikó, Mócsai, Gábor, Rühl, Ralph, Szegedi, Andrea, Töröcsik, Dániel, Zouboulis, Christos C.   +12 more
core   +1 more source

Inflammatory and Immunological Basis of Periodontal Diseases

Journal of Periodontal Research, EarlyView.
The periodontal lesion emerges as an evolving immunological battlefield, where host–microbiome interactions, dysregulated immune responses, fragile resolution mechanisms, and inflammophilic dysbiosis converge to shift the balance from homeostasis to unrestrained tissue destruction.
Giacomo Baima, Marion Arce, Mario Romandini, Thomas Van Dyke   +3 more
wiley   +1 more source