Results 61 to 70 of about 20,106 (166)

Polyomavirus Drives Cerebellar Lesions in AIDS Monkeys With Ataxia

MedComm, Volume 7, Issue 11, November 2026.
Chronic SIV‐infected macaques with ataxia develop severe cerebellar lesions driven by simian polyomavirus 40 (SV40) infection. SV40 preferentially infects cerebellar granule cells, inducing pyroptosis and an aberrant proliferative state. Pyroptotic neuronal injury promotes microglial recruitment and activation, amplifying local neuroinflammation and ...
Tian‐Zhang Song, Li‐Rong Zhang, Yun‐Mei Wang, Yan Hu, Qing Li, Ren‐Rong Tian, Liu‐Meng Yang, Si‐Dong Xiong, Dong‐Dong Wu, Yong‐Tang Zheng   +9 more
wiley   +1 more source

Table_1_Eubacterium rectale Attenuates HSV-1 Induced Systemic Inflammation in Mice by Inhibiting CD83.docx

, 2021
The purpose of this study was to determine whether administration of the microorganism Eubacterium rectale (E. rectale) could regulate dendritic cell (DC) activation and systemic inflammation in herpes simplex virus type 1-induced Behçet’s disease (BD ...
Hye-Myung Ryu (3110241), Hyoun-Ah Kim (3556952), Chang-Hee Suh (2503150), S. M. Shamsul Islam (10502510), Hasan M. Sayeed (10502513), Hae-Ok Byun (1732708), Ju-Yang Jung (3556964), Seonghyang Sohn (10502516)   +7 more
core   +1 more source

Relationship between Helicobacter pylori Infection and Plasmacytoid and Myeloid Dendritic Cells in Peripheral Blood and Gastric Mucosa of Children

Mediators of Inflammation, 2019
Purpose. To investigate the frequency and activation status of peripheral plasmacytoid DCs (pDCs) and myeloid DCs (mDCs) as well as gastric mucosa DC subset distribution in Helicobacter pylori- (H. pylori-) infected and noninfected children.
Anna Helmin-Basa, Małgorzata Wiese-Szadkowska, Anna Szaflarska-Popławska, Maciej Kłosowski, Milena Januszewska, Magdalena Bodnar, Andrzej Marszałek, Lidia Gackowska, Jacek Michalkiewicz   +8 more
doaj   +1 more source

B Cells are Activated via a Nanoporous Interface that Stabilizes Microvilli and Engages Mechanosensitive Ion Channels

Advanced Science, Volume 13, Issue 59, 23 October 2026.
B cells can be activated independently of antigen recognition via mechanical stimulation through nanoporous substrates. Exposure to such substrates induced B cell microvilli extension into the pores, intracellular Ca2+ signaling, phosphorylation of signaling proteins, and CD69 expression.
Nozie D. Aghaizu, Willi Weber, Nadine Strempel, Asya Polat, Enrico Klotzsch   +4 more
wiley   +1 more source

CD83 억제제를 유효성분으로 포함하는 베체트병의 예방 또는 치료용 조성물

, 2021
본 발명은 CD83 억제제를 유효성분으로 포함하는 베체트병의 예방 또는 치료용 조성물을 제공한다. 본 발명에 따르면, 베체트병 마우스에서 CD83을 발현하는 세포의 빈도가 유의하게 높고, CD83 발현 세포의 증감과 베체트병 증상 사이에 관련성이 있음을 확인한 바, 본 발명에 따른 CD83 억제제를 이용하여 CD83의 발현을 조절함으로써, 베체트병 진단, 예방, 및 치료에 효과적으로 사용될 수 있다.
손성향
core   +1 more source

UFL1‐Mediated UFMylation of ENO1 Restrains Aerobic Glycolysis and Colorectal Cancer Progression

Advanced Science, Volume 13, Issue 59, 23 October 2026.
UFMylation restrains aerobic glycolysis and colorectal cancer progression by modifying the glycolytic enzyme ENO1. Pharmacological enhancement of the UFL1–ENO1 interaction by the FDA‐approved antibiotic torezolid promotes ENO1 UFMylation, suppresses tumor metabolism, and sensitizes colorectal cancer to chemotherapy, revealing an actionable metabolic ...
Xiuqing Ma, Rui Wan, Yueyuan Zhong, Ziyang Cui, Xuan Zhang, Xiaoqiang He, Rong Wang, Lei Huang, Wan‐Yang Sun, Rong‐Rong He, Yang Zhou, Jianshuang Li, Li Shen, Shao‐Hua Wang, Tongzheng Liu   +14 more
wiley   +1 more source

Post-transcriptional regulation of CD83 expression by AUF1 proteins

, 2012
Mature dendritic cells (DC), activated lymphocytes, mononuclear cells and neutrophils express CD83, a surface protein apparently necessary for effective DC-mediated activation of naive T-cells and T-helper cells, thymic T-cell maturation and the ...
Schirmer, Susann, Chemnitz, Jan, Susann Schirmer, Christina Ehlers, Jan Chemnitz, Joachim Hauber, Hauber, Joachim, Ralph H. Kehlenbach, Kehlenbach, Ralph H., Ehlers, Christina   +9 more
core   +1 more source

Redirecting Monocyte Differentiation With Engineered Extracellular Vesicles for Glioma Immunotherapy

Advanced Science, Volume 13, Issue 59, 23 October 2026.
A dual‐targeting engineered extracellular vesicles (M1‐CS‐EVs) platform is developed to redirect monocytes differentiation into anti‐tumor macrophages for glioma immunotherapy. This nanoplatform combines CAR‐mediated tumor recognition with localized CD47 blockade, leading to synergistic immune activation and potent suppression of tumor progression in ...
Yuanwei Pan, Xuan Liu, Qian‐Fang Meng, Lei Cao, Rongrong Li, Yangtao Xu, Jing Zhang, Chenchen Zhao, Lang Rao, Chen Yu   +9 more
wiley   +1 more source

Langerin-expressing and CD83-expressing cells in oral lichen planus lesions

, 2007
OBJECTIVE: Dendritic Langerhans cells (LCs) have been attributed a role in the pathogenesis of lichen planus as autoantigen-presenting cells initiating expansion of autoreactive T cells.
Zellin, Göran,, Jenny Gustafson, Christina Eklund, Gustafson, Jenny,, Göran Zellin, Magnusson, Bengt,, Bengt Hasséus, Wallström, Mats,, Bengt Magnusson, Hasséus, Bengt,, Mats Wallström, Eklund, Christina,   +11 more
core   +1 more source

Regulation des Zelloberflächenmoleküls CD83 durch das Epstein-Barr Virus und Analyse seiner Funktion [PDF]

, 2002
EBV is a γ-herpes virus which is able to infect human resting B-cells and to transform them into permanently growing lymphoblastoid cell lines (LCLs).
Dudziak, Diana
core   +1 more source